Acesso livre
Acesso livre

Geriatria

Diretriz sobre potenciais interações droga-droga entre ritonavir reforçado por nirmatrelvir (Paxlovid) e medicações concomitantes; antiarrítmicos, anticoagulantes orais, imunossupressores, anticonvulsivantes, antineoplásicos e neuropsiquiátricos estão entre os medicamentos de preocupação.

13 Jan, 2022 | 12:12h

The COVID-19 Treatment Guidelines Panel’s Statement on Potential Drug-Drug Interactions Between Ritonavir-Boosted Nirmatrelvir (Paxlovid) and Concomitant Medications – NIH COVID-19 Treatment Guidelines Panel

Comentários:

Pfizer antiviral pills may be risky with other medications – NBC News

The New COVID-19 Pill, Paxlovid, Interacts with Many Medications: Cardiac Patients Take Note – The Skeptical Cardiologist

Ver também: What’s New in the Guidelines – NIH COVID-19 Treatment Guidelines


Estimativa de prevalência global de demência em 2019 e prevalência prevista para 2050: uma análise do Global Burden of Disease Study 2019.

12 Jan, 2022 | 12:52h

Estimation of the global prevalence of dementia in 2019 and forecasted prevalence in 2050: an analysis for the Global Burden of Disease Study 2019 – The Lancet Public Health

Comunicado de imprensa: Global dementia cases set to triple by 2050 unless countries address risk factors – The Lancet

Comentários:

Forecasting the prevalence of dementia – The Lancet Public Health

Dementia cases expected to almost triple across the world by 2050 – BBC

Number of adults with dementia to exceed 150m by 2050, study finds – The Guardian

 

Comentário no Twitter (fio – clique para saber mais)

 


Diretriz AAN | Tratamento oral e tópico da polineuropatia diabética dolorosa.

10 Jan, 2022 | 12:25h

Oral and Topical Treatment of Painful Diabetic Polyneuropathy: Practice Guideline Update Summary: Report of the AAN Guideline Subcommittee – Neurology

Comunicado de imprensa: AAN Issues Guideline for Treatment of Painful Diabetic Neuropathy – American Academy of Neurology


Estudo randomizado | Em pacientes idosos submetidos a cirurgia para fratura de quadril, a anestesia regional não reduziu a incidência de delirium pós-cirúrgico em comparação com a anestesia geral.

10 Jan, 2022 | 12:15h

Effect of Regional vs General Anesthesia on Incidence of Postoperative Delirium in Older Patients Undergoing Hip Fracture Surgery: The RAGA Randomized Trial – JAMA (link para o resumo – $ para o texto completo)

Comentário: China-wide study will boost understanding of fatal surgical complication – University of Birmingham

Conteúdos relacionados:

RCT: Spinal Anesthesia not Superior to General Anesthesia for Hip Surgery in Older Adults.

RCT: Similar long-term survival after combined epidural–general anesthesia vs. general anesthesia alone.

Delirium in Older Patients after Combined Epidural–General Anesthesia or General Anesthesia for Major Surgery: A Randomized Trial – Anesthesiology


Em um amplo estudo de coorte retrospectivo que analisou pacientes de 65 anos de idade ou mais com fibrilação atrial, o tratamento com rivaroxabam comparado com apixabam foi associado com risco aumentado de eventos isquêmicos ou hemorrágicos maiores.

10 Jan, 2022 | 11:49h

Association of Rivaroxaban vs Apixaban With Major Ischemic or Hemorrhagic Events in Patients With Atrial Fibrillation – JAMA

Comentário: Apixaban Appears Safer, More Effective Than Rivaroxaban in Medicare Study – TCTMD

Conteúdo relacionado:

Meta-Analysis Comparing Apixaban Versus Rivaroxaban for Management of Patients With Nonvalvular Atrial Fibrillation – American Journal of Medicine

Observational Study Suggests Apixaban May Be a Better Choice than Rivaroxaban for Patients with Atrial Fibrillation


Estudo de coorte retrospectivo | Em pacientes com tromboembolismo venoso (TEV), o tratamento com apixabam foi associado com menores taxas de TVE recorrente e sangramento em comparação ao rivaroxabam.

10 Jan, 2022 | 11:47h

Risk for Recurrent Venous Thromboembolism and Bleeding With Apixaban Compared With Rivaroxaban: An Analysis of Real-World Data – Annals of Internal Medicine

Comentários:

Apixaban shows superior effectiveness, safety compared to rivaroxaban – ACP Internist

Recurrent VTE and Bleeding With Apixaban vs. Rivaroxaban – American College of Cardiology


Prevenção de náusea e vômito induzidos por quimioterapia em pacientes idosos.

17 Dez, 2021 | 12:04h

Prevention of Chemotherapy-Induced Nausea and Vomiting in the Older Patient: Optimizing Outcomes – Drugs & Aging (se o acesso a este link for pago, tente este)


Diretriz de prática clínica baseada em evidências | Tratamento de fraturas de quadril em idosos.

16 Dez, 2021 | 12:58h

Management of Hip Fractures in Older Adults Evidence-Based Clinical Practice Guideline – American Academy of Orthopaedic Surgeons

Resumo: Management of Hip Fractures in Older Adults – American Academy of Orthopaedic Surgeons

Comunicado de imprensa: AAOS Updates Clinical Practice Guideline for Management of Hip Fractures in Older Adults


Consenso de especialistas e diretriz prática | Perspectiva global sobre a melhora no cuidado do paciente com infecção de trato urinário não complicada.

15 Dez, 2021 | 12:36h

A global perspective on improving patient care in uncomplicated urinary tract infection: Expert consensus and practical guidance – Journal of Global Antimicrobial Resistance


Subtipos propostos de “long Covid” e suas respectivas terapias potenciais.

14 Dez, 2021 | 16:18h

Proposed subtypes of post-COVID-19 syndrome (or long-COVID) and their respective potential therapies – Reviews in Medical Virology

Conteúdos relacionados:

EuGMS Guidance: Management of post-acute COVID-19 patients in geriatric rehabilitation.

Addressing Post-COVID Symptoms: A Guide for Primary Care Physicians.

Global surveillance, research, and collaboration needed to improve understanding and management of long COVID.

Provocative study suggests that persistent physical symptoms after COVID-19 infection may be associated more with the belief in having been infected with SARS-CoV-2 than with having laboratory-confirmed COVID-19 infection.

Update to post-acute sequelae of SARS-CoV-2 infection: Caring for the ‘long-haulers’.

Systematic Review: Short-term and long-term rates of postacute sequelae of SARS-CoV-2 infection.

WHO Consensus: A clinical case definition of post COVID-19 condition (Long Covid).

Characterizing long COVID: a living systematic review.

Long Covid – The illness narratives.

New guidelines to help doctors manage long COVID patients published.

M-A: More than 50 long-term effects of COVID-19. (vários artigos sobre o tema)


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