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Medicina de Família

Nova diretriz no Reino Unido | Autoisolamento para pessoas com COVID-19 pode encerrar após 5 dias completos e 2 testes rápidos negativos – “O período padrão de autoisolamento continua sendo de 10 dias, e o paciente só deve deixá-lo precocemente depois de fazer 2 testes rápidos e não ter febre, conforme a orientação.”

17 Jan, 2022 | 13:21h

Self-isolation for those with COVID-19 can end after 5 full days following 2 negative LFD tests – Department of Health and Social Care

 

Comentário no Twitter (fio – clique para saber mais)

 


Gestantes não vacinadas estão sob maior risco de complicações decorrentes da Covid e de morte do bebê.

17 Jan, 2022 | 13:19h

Unvaccinated pregnant people are at higher risk for Covid complications and newborn deaths – STAT

Estudo original: SARS-CoV-2 infection and COVID-19 vaccination rates in pregnant women in Scotland – Nature Medicine


Dados mostram que as vacinas contra COVID protegem as gestantes.

17 Jan, 2022 | 13:17h

COVID vaccines safely protect pregnant people: the data are in – Nature

Conteúdos relacionados:

COVID-19 vaccination in pregnancy—number needed to vaccinate to avoid harm.

A case-controlled study showed Covid-19 vaccination during early pregnancy was not associated with increased risk of first-trimester miscarriage.

Editorial: Covid-19 treatments and vaccines must be evaluated in pregnancy.

AstraZeneca vaccination not linked to reduced fertility rates and adverse birth outcomes.

Cohort study: Vaccinated pregnant patients had 90% lower risk of severe or critical Covid-19 compared with unvaccinated pregnant patients.

Two observational studies suggest spontaneous abortion is not increased following COVID-19 mRNA vaccination during pregnancy.

Study shows high effectiveness of the Pfizer mRNA COVID-19 vaccine in pregnancy.

5 Crucial Things to Know About COVID-19 Vaccines and Pregnancy.

CDC Guidance: Pregnant people should be vaccinated against COVID-19.

ACOG and SMFM Recommend COVID-19 Vaccination for Pregnant Individuals – “ACOG encourages its members to enthusiastically recommend vaccination to their patients.”

Cohort study: Pfizer/BioNTech COVID vaccine associated with 78% lower risk of Covid-19 in pregnancy.


Considerações cardiovasculares perioperatórias antes de cirurgia não cardíaca eletiva em pacientes com histórico de Covid-19.

17 Jan, 2022 | 13:16h

Perioperative Cardiovascular Considerations Prior to Elective Noncardiac Surgery in Patients With a History of COVID-19 – JAMA Surgery

Conteúdos relacionados:

Guideline: SARS‐CoV‐2 infection, COVID‐19 and timing of elective surgery

Study from 116 countries suggests surgery should be delayed for at least seven weeks following a COVID-19 diagnosis to reduce mortality risk

BJS commission on surgery and perioperative care post-COVID-19.

The risk of postoperative complications following major elective surgery in active or resolved COVID-19 in the United States – Major, elective surgery 0–4 weeks after Covid-19 is associated with greatly increased risk of postoperative complications; surgery performed 4–8 weeks after infection is still associated with an increased risk of pneumonia.

ASA Guidance: Preoperative testing for COVID-19 is essential, regardless of vaccination.

Position statement: Perioperative management of post-COVID-19 surgical patients.

Cohort study: Postoperative in-hospital mortality of patients with COVID-19 infection was more than double that in patients without COVID-19


Fluvoxamina para Covid-19: o que médicos e farmacêuticos precisam saber.

17 Jan, 2022 | 13:14h

Fluvoxamine: What Prescribers and Pharmacists Need to Know – Covid-19 Advisory for Ontario

Conteúdos relacionados:

Fluvoxamine for the early treatment of SARS-CoV-2 Infection: a review of current evidence.

RCT: Early treatment with fluvoxamine reduced the risk of emergency care and hospitalization among patients with COVID-19.

[Preprint] RCT: Fluvoxamine reduced the risk for ER visits and hospitalization among patients with Covid-19.

Opinion | Could this be our first effective, inexpensive, widely available outpatient treatment for COVID-19? (It’s fluvoxamine).

Preliminary study shows fluvoxamine may reduce clinical deterioration in outpatients with symptomatic COVID-19

 

Comentário no Twitter

 


Estudo randomizado | Colchicina não reduz significativamente a necessidade de intubação ou a mortalidade em 28 dias em pacientes internados com Covid-19.

17 Jan, 2022 | 13:13h

Effect of Colchicine vs Usual Care Alone on Intubation and 28-Day Mortality in Patients Hospitalized With COVID-19: A Randomized Clinical Trial – JAMA Network Open

Conteúdos relacionados:

M-A: Colchicine doesn’t lessen COVID-19 severity or stave off risk of death.

RECOVERY Trial: In patients admitted to hospital with COVID-19, Colchicine did not reduce 28-day mortality, duration of hospital stay, or risk of progressing to invasive mechanical ventilation or death.

[Preprint] PRINCIPLE RCT: Colchicine does not improve time to recovery in outpatients with Covid-19 at higher risk of complications.

COLCORONA RCT: Colchicine for community-treated patients with COVID-19 – findings suggest it may lower death and hospital admission rates, but further studies are required.

[Preprint] RECOVERY Trial: Colchicine does not improve outcomes in patients admitted to hospital with COVID-19.

 

Comentário no Twitter

 


Perspectiva | Ômicron está nos forçando a repensar sobre COVID leve.

17 Jan, 2022 | 13:10h

Omicron Is Forcing Us to Rethink Mild COVID – The Atlantic


Revisão | Enxaqueca.

17 Jan, 2022 | 12:59h

Migraine – Nature Reviews Disease Primers (se o acesso a este link for pago, tente este)

Infográfico: Migraine (se o acesso a este link for pago, tente este)


M-A | Contraceptivos orais combinados podem melhorar a sintomatologia pré-menstrual, mas não ajudam nos sintomas depressivos pré-menstruais.

17 Jan, 2022 | 12:03h

Efficacy of combined oral contraceptives for depressive symptoms and overall symptomatology in premenstrual syndrome: pairwise and network meta-analysis of randomized trials – American Journal of Obstetrics & Gynecology

Comentário: ‘Optimal’ treatment for premenstrual depressive symptoms remains elusive – Healio (necessário cadastro gratuito)


Estudo mostra que as vacinas contra COVID-19 oferecem proteção duradoura contra internações e morte.

13 Jan, 2022 | 21:23h

Duration of Protection against Mild and Severe Disease by Covid-19 Vaccines – New England Journal of Medicine

Comunicado de imprensa: Study shows COVID-19 vaccines offer lasting protection – University of North Carolina at Chapel Hill


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