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Clínica Médica

Nova diretriz no Reino Unido | Autoisolamento para pessoas com COVID-19 pode encerrar após 5 dias completos e 2 testes rápidos negativos – “O período padrão de autoisolamento continua sendo de 10 dias, e o paciente só deve deixá-lo precocemente depois de fazer 2 testes rápidos e não ter febre, conforme a orientação.”

17 Jan, 2022 | 13:21h

Self-isolation for those with COVID-19 can end after 5 full days following 2 negative LFD tests – Department of Health and Social Care

 

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Considerações cardiovasculares perioperatórias antes de cirurgia não cardíaca eletiva em pacientes com histórico de Covid-19.

17 Jan, 2022 | 13:16h

Perioperative Cardiovascular Considerations Prior to Elective Noncardiac Surgery in Patients With a History of COVID-19 – JAMA Surgery

Conteúdos relacionados:

Guideline: SARS‐CoV‐2 infection, COVID‐19 and timing of elective surgery

Study from 116 countries suggests surgery should be delayed for at least seven weeks following a COVID-19 diagnosis to reduce mortality risk

BJS commission on surgery and perioperative care post-COVID-19.

The risk of postoperative complications following major elective surgery in active or resolved COVID-19 in the United States – Major, elective surgery 0–4 weeks after Covid-19 is associated with greatly increased risk of postoperative complications; surgery performed 4–8 weeks after infection is still associated with an increased risk of pneumonia.

ASA Guidance: Preoperative testing for COVID-19 is essential, regardless of vaccination.

Position statement: Perioperative management of post-COVID-19 surgical patients.

Cohort study: Postoperative in-hospital mortality of patients with COVID-19 infection was more than double that in patients without COVID-19


Fluvoxamina para Covid-19: o que médicos e farmacêuticos precisam saber.

17 Jan, 2022 | 13:14h

Fluvoxamine: What Prescribers and Pharmacists Need to Know – Covid-19 Advisory for Ontario

Conteúdos relacionados:

Fluvoxamine for the early treatment of SARS-CoV-2 Infection: a review of current evidence.

RCT: Early treatment with fluvoxamine reduced the risk of emergency care and hospitalization among patients with COVID-19.

[Preprint] RCT: Fluvoxamine reduced the risk for ER visits and hospitalization among patients with Covid-19.

Opinion | Could this be our first effective, inexpensive, widely available outpatient treatment for COVID-19? (It’s fluvoxamine).

Preliminary study shows fluvoxamine may reduce clinical deterioration in outpatients with symptomatic COVID-19

 

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Estudo randomizado | Colchicina não reduz significativamente a necessidade de intubação ou a mortalidade em 28 dias em pacientes internados com Covid-19.

17 Jan, 2022 | 13:13h

Effect of Colchicine vs Usual Care Alone on Intubation and 28-Day Mortality in Patients Hospitalized With COVID-19: A Randomized Clinical Trial – JAMA Network Open

Conteúdos relacionados:

M-A: Colchicine doesn’t lessen COVID-19 severity or stave off risk of death.

RECOVERY Trial: In patients admitted to hospital with COVID-19, Colchicine did not reduce 28-day mortality, duration of hospital stay, or risk of progressing to invasive mechanical ventilation or death.

[Preprint] PRINCIPLE RCT: Colchicine does not improve time to recovery in outpatients with Covid-19 at higher risk of complications.

COLCORONA RCT: Colchicine for community-treated patients with COVID-19 – findings suggest it may lower death and hospital admission rates, but further studies are required.

[Preprint] RECOVERY Trial: Colchicine does not improve outcomes in patients admitted to hospital with COVID-19.

 

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Estudo de coorte | Pacientes que perderam peso via cirurgia bariátrica podem estar sob menor risco de ter Covid-19 grave, em comparação a pacientes não submetidos a intervenção cirúrgica como tratamento de sua obesidade.

17 Jan, 2022 | 13:11h

Association of Weight Loss Achieved Through Metabolic Surgery With Risk and Severity of COVID-19 Infection – JAMA Surgery

Comentários:

Is COVID-19 the Newest Comorbidity of Obesity Mitigated by Bariatric Surgery? – JAMA Surgery

Can weight loss help protect against Covid-19? – CNN


Perspectiva | Ômicron está nos forçando a repensar sobre COVID leve.

17 Jan, 2022 | 13:10h

Omicron Is Forcing Us to Rethink Mild COVID – The Atlantic


Diretriz de posicionamento AAN | Questões de consentimento no tratamento do AVC isquêmico agudo.

17 Jan, 2022 | 13:07h

Consent Issues in the Management of Acute Ischemic Stroke: AAN Position Statement – Neurology

Comunicado de imprensa: Who gives consent for treatment when a person with stroke cannot? – American Academy of Neurology


Top 10 | Os principais estudos de 2021 que fizeram a diferença na prática clínica cardiológica.

17 Jan, 2022 | 13:03h

Feature | The Top Ten: Key Trials in 2021 Making a Difference in Clinical Practice – American College of Cardiology


Revisão sistemática | Limiares restritivos de transfusão podem reduzir as transfusões de forma segura em até 41% em uma ampla variedade de contextos clínicos.

17 Jan, 2022 | 13:01h

Transfusion thresholds for guiding red blood cell transfusion – Cochrane Library

Resumo: Is it safe to use lower blood counts (haemoglobin levels) as a trigger for blood transfusion in order to give fewer blood transfusions? – Cochrane Library

Conteúdos relacionados:

RCT: Among patients with acute MI and anemia, a restrictive transfusion strategy resulted in a noninferior rate of major cardiovascular events compared to a liberal transfusion strategy

Randomized trial: Liberal vs. restrictive transfusion thresholds in extremely low-birth-weight infants

Meta-Analysis: Effects of Restrictive vs. Liberal Transfusion Strategies on Longer-term Outcomes After Cardiac Surgery

Randomized Trial: In Patients Undergoing Cardiac Surgery, A Restrictive Transfusion Approach Does Not Increase the Risk of Acute Kidney Injury

Effects of restrictive red blood cell transfusion on the prognoses of adult patients undergoing cardiac surgery: a meta-analysis of randomized controlled trials – Critical Care

Research: Restrictive or Liberal Red-Cell Transfusion for Cardiac Surgery

Transfusion Requirements After Cardiac Surgery: The TRACS Randomized Controlled Trial – JAMA

 

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Revisão | Enxaqueca.

17 Jan, 2022 | 12:59h

Migraine – Nature Reviews Disease Primers (se o acesso a este link for pago, tente este)

Infográfico: Migraine (se o acesso a este link for pago, tente este)


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