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Emergências e Terapia Intensiva

Recomendações da ECMM/ISHAM para o manejo clínico da mucormicose associada à COVID-19 em países de baixa e média rendas.

18 Jun, 2021 | 10:34h

ECMM/ISHAM recommendations for clinical management of COVID -19 associated mucormycosis in low- and middle-income countries – Mycosis


Estudo de coorte | Desfechos relacionados a deglutição e voz em pacientes hospitalizados com COVID-19.

18 Jun, 2021 | 10:33h

Swallowing and Voice Outcomes in Patients Hospitalized With COVID-19: An Observational Cohort Study – Archives of Physical Medicine and Rehabilitation

Estudo relacionado: Characterization of dysphagia and laryngeal findings in COVID-19 patients treated in the ICU—An observational clinical study – PLOS One


Comentário sobre estudo | História da hipotermia na parada cardíaca, 2002-2021 (RIP).

18 Jun, 2021 | 10:29h

A history of hypothermia for cardiac arrest, 2002-2021 (RIP) – PulmCrit

Estudo original: RCT: In patients with coma after out-of-hospital cardiac arrest, targeted hypothermia did not improve outcomes.

 

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Estudo randomizado | Tofacitinibe reduziu o risco de morte ou insuficiência respiratória em pacientes hospitalizados com pneumonia por Covid-19.

17 Jun, 2021 | 11:06h

Tofacitinib in Patients Hospitalized with Covid-19 Pneumonia – New England Journal of Medicine

Comunicado de imprensa: Data Published in New England Journal of Medicine Shows Pfizer’s Tofacitinib Meets Primary Endpoint in Brazilian Study in Patients Hospitalized with COVID-19 Pneumonia

 

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[Preprint] Estudo RECOVERY descobre que a combinação de anticorpo monoclonal Regeneron reduz as mortes de pacientes hospitalizados com COVID que não desenvolveram sua própria resposta imunológica.

17 Jun, 2021 | 11:04h

Comunicado de imprensa: RECOVERY trial finds Regeneron’s monoclonal antibody combination reduces deaths for hospitalised COVID-19 patients who have not mounted their own immune response

Estudo original (preprint): Casirivimab and imdevimab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial – medRxiv

Comentários: Monoclonal antibodies cut risk of dying from COVID-19—but only in some patients – Science E Antibody combo cuts COVID deaths by 20% in very ill seronegative patients – CIDRAP E Regeneron antibody saves lives in some hospitalized Covid patients, study finds – STAT E Expert reaction to press release from the RECOVERY trial reporting that Regeneron’s monoclonal antibody combination reduces deaths for hospitalised COVID-19 patients who have not mounted their own immune response – Science Media Centre

 

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Agora, o CDC chama a variante Delta do coronavírus de “variante de preocupação”.

17 Jun, 2021 | 11:02h

CDC now calls coronavirus Delta variant a ‘variant of concern’ – CNN

Diretriz: SARS-CoV-2 Variant Classifications and Definitions – Centers for Disease Control and Prevention

 

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Série de casos | 7 casos de miocardite após vacinação baseada em mRNA contra COVID-19.

17 Jun, 2021 | 11:00h

Myocarditis after BNT162b2 and mRNA-1273 Vaccination – Circulation

Comentário: Study details the treatment of COVID-19 vaccine-associated myocarditis-like illness in 7 patients – News Medical

Relacionado: CDC says heart inflammation cases were higher than expected in 16- to 24-year-olds after second Covid vaccine shot, but still rare. E Israel reports link between rare cases of heart inflammation and COVID-19 vaccination in young men. E CDC is investigating several reports that teenagers and young adults may have developed myocarditis after receiving mRNA vaccines. Most cases were mild, more often in males than females, more often following dose 2 than dose 1, and typically, within 4 days after vaccination.


Série de casos | Achados clínicos e de ressonância magnética em 4 casos de miocardite após vacinação baseada em mRNA contra COVID-19.

17 Jun, 2021 | 10:58h

Possible Association Between COVID-19 Vaccine and Myocarditis: Clinical and CMR Findings – JACC: Cardiovascular Imaging

Comentário: Possible Association Between COVID-19 Vaccine and Myocarditis – American College of Cardiology

Relacionado: CDC says heart inflammation cases were higher than expected in 16- to 24-year-olds after second Covid vaccine shot, but still rare. E Israel reports link between rare cases of heart inflammation and COVID-19 vaccination in young men. E CDC is investigating several reports that teenagers and young adults may have developed myocarditis after receiving mRNA vaccines. Most cases were mild, more often in males than females, more often following dose 2 than dose 1, and typically, within 4 days after vaccination.


Série de casos | Miocardite sintomática aguda em 7 adolescentes após vacinação baseada em mRNA contra COVID-19.

17 Jun, 2021 | 10:57h

Symptomatic Acute Myocarditis in Seven Adolescents Following Pfizer-BioNTech COVID-19 Vaccination – Pediatrics

Relacionado: CDC says heart inflammation cases were higher than expected in 16- to 24-year-olds after second Covid vaccine shot, but still rare. E Israel reports link between rare cases of heart inflammation and COVID-19 vaccination in young men. E CDC is investigating several reports that teenagers and young adults may have developed myocarditis after receiving mRNA vaccines. Most cases were mild, more often in males than females, more often following dose 2 than dose 1, and typically, within 4 days after vaccination.


Estudo randomizado | Em paciente em coma após parada cardíaca fora do ambiente hospitalar, a hipotermia induzida não melhorou os desfechos.

17 Jun, 2021 | 10:56h

Hypothermia versus Normothermia after Out-of-Hospital Cardiac Arrest – New England Journal of Medicine

Comunicado de imprensa: Induced hypothermia after cardiac arrest did not improve survival – Lund University

Infográfico: The TTM2 Trial – CanadianEM

Comentário: Hypothermia or Normothermia after Cardiac Arrest – NEJM Resident 360

Vídeo: TTM2 Results Presentation Livestream – Critical Care Reviews

 

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