Cirurgia Gastrintestinal
Estudo randomizado | Realimentação oral imediata em pacientes com pancreatite aguda leve e moderada.
22 Jul, 2021 | 12:50hImmediate Oral Refeeding in Patients With Mild and Moderate Acute Pancreatitis: A Multicenter, Randomized Controlled Trial (PADI trial) – Annals of Surgery (link para o resumo – $ para o texto completo)
Diretrizes SAGES para o tratamento cirúrgico do refluxo gastresofágico.
21 Jul, 2021 | 09:50hSAGES guidelines for the surgical treatment of gastroesophageal reflux (GERD) – Surgical Endoscopy
Atualização da Diretriz de Prática Clínica da AGA para quimioprevenção do câncer colorretal.
16 Jul, 2021 | 09:47h
Comentário no Twitter
Out now in @AGA_CGH: AGA Clinical Practice Update on Chemoprevention for Colorectal Neoplasia. Had great time working on this with @AasmaShaukatMD & @seth_crockett. Hope it's a useful reference! @AmerGastroAssn
https://t.co/UB5hFMq6hc pic.twitter.com/KwHeKjU2dk— Peter Liang, MD MPH (@petersliang) February 19, 2021
M-A | Anti-inflamatórios não hormonais (AINH), fluidos intravenosos, stents pancreáticos e suas combinações para a prevenção de pancreatite pós-colangiopancreatografia retrógrada endoscópica.
16 Jul, 2021 | 09:41hNon-steroidal anti-inflammatory drugs, intravenous fluids, pancreatic stents, or their combinations for the prevention of post-endoscopic retrograde cholangiopancreatography pancreatitis: a systematic review and network meta-analysis – The Lancet Gastroenterology & Hepatology (link para o resumo – $ para o texto completo)
Comentário no Twitter
New research – Akshintala et al – NSAIDs, intravenous fluids, pancreatic stents, or their combinations for the prevention of post-ERCP #pancreatitis: a systematic review and network meta-analysishttps://t.co/2Sh8WhqZRD#GITwitter #endoscopy #ERCP pic.twitter.com/nvAKXyPv13
— The Lancet Gastroenterology & Hepatology (@LancetGastroHep) June 30, 2021
Impacto global do câncer atribuído ao consumo de álcool – “Em termos globais, estima-se que 741.300 casos, ou 4,1% de todos os novos casos de câncer em 2020, foram atribuídos ao consumo de álcool.”
14 Jul, 2021 | 11:36hComunicado de imprensa: Alcohol consumption linked to more than 740,000 new cancer cases in 2020 – The Lancet
Comentários: Alcohol caused 740,000 cancer cases globally last year – study – The Guardian E Expert reaction to study of alcohol and cancer – Science Media Centre
Outro estudo randomizado avaliou a eficácia e a qualidade de vida no tratamento somente com antibióticos da apendicite aguda não complicada.
13 Jul, 2021 | 11:16hA Randomized Clinical Trial Evaluating the Efficacy and Quality of Life of Antibiotic-only Treatment of Acute Uncomplicated Appendicitis: Results of the COMMA Trial – Annals of Surgery (link para o resumo – $ para o texto completo)
Relacionado: A Randomized trial comparing antibiotics with appendectomy for appendicitis E Antibiotics alone for uncomplicated appendicitis: Oral Moxifloxacin almost as good as intravenous Ertapenem + oral Levofloxacin E Observational study: 67.1% success rate with nonoperative management of children with uncomplicated appendicitis E Randomized Trial: Quality of Life and Patient Satisfaction at 7-Year Follow-up of Antibiotic Therapy vs. Appendectomy for Uncomplicated Acute Appendicitis E Meta-Analysis: Antibiotic Treatment vs. Appendectomy for Uncomplicated Acute Appendicitis in Adults and Children E Nonoperative treatment for nonperforated appendicitis in children: a systematic review and meta-analysis – Pediatric Surgery International
Comentário no Twitter
The debate continues!
Another RCT comparing antibiotics to surgery for uncomplicated appendicitis – COMMA trial from 🇮🇪
Recurrence within 1-year : 25% after AB
Superior quality of life at 3 and 12mo after surgery.https://t.co/Yv51qpxchb
— Ville Sallinen (@villesallinen) July 11, 2021
Estudo randomizado | Eficácia de longo prazo da quimiorradioterapia neoadjuvante somada à cirurgia para o tratamento de carcinoma esofágico de células escamosas localmente avançado.
13 Jul, 2021 | 11:09h
Comentário no Twitter
Long-term outcomes from the NEOCRTEC5010 demonstrated the survival benefit of neoadjuvant chemoradiotherapy followed by surgery compared with surgery alone for patients with locally advanced esophageal squamous cell carcinoma https://t.co/UBBEEAynsy
— JAMA Surgery (@JAMASurgery) June 29, 2021
Ranitidina absolvida? Estudo do FDA mostra que a ranitidina não é convertida ao carcinógeno NDMA, independentemente da dieta.
12 Jul, 2021 | 11:23hEditorial: Ranitidine and Risk of N-Nitrosodimethylamine (NDMA) Formation
Comentário: Ranitidine: FDA finds no evidence of elevated NDMA, regardless of diet
Comentário no Twitter
Despite ranitidine (zantac) being pulled from market last year, a new study from the FDA did not find evidence that it increases concentrations of the carcinogenic metabolite people were worried about (i.e., it's probably safe). From @JAMA_current https://t.co/AdRic2GdXS
— Zack Williams (@QuantPsychiatry) June 28, 2021
In this crossover, randomized clinical trial, oral ranitidine did not significantly increase 24-hour urinary excretion of NDMA when administered with a noncured-meats diet or a cured-meats diet. https://t.co/EszRvfJOFJ
— JAMA (@JAMA_current) June 28, 2021
Estudo randomizado | Outro estudo mostra a segurança do tratamento ambulatorial sem antibióticos na diverticulite aguda leve.
12 Jul, 2021 | 11:19hEfficacy and Safety of Non-Antibiotic Outpatient Treatment in Mild Acute Diverticulitis (DINAMO-study): A Multicentre, Randomised, Open-Label, Non-Inferiority Trial – Annals of Surgery (link para o resumo – $ para o texto completo)
Relacionado: State of the Art Review: Management of colonic diverticulitis E Treatment of Uncomplicated Acute Diverticulitis Without Antibiotics: A Systematic Review and Meta-analysis – Diseases of the Colon & Rectum E Antibiotics Do Not Reduce Length of Hospital Stay for Uncomplicated Diverticulitis in a Pragmatic Double-Blind Randomized Trial – Clinical Gastroenterology and Hepatology E Randomized Trial: Antibiotic Avoidance Associated with Similar Long-term Outcomes in Uncomplicated Diverticulitis
Comentário no Twitter
Another (final?) nail in the coffin for antibiotics in uncomplicated diverticulitis? DINAMO study from Spain – Outpatient treatment with antibiotics versus symptomatic Tx.
No difference in hospitalization rate or revisits to ER.https://t.co/wOc3tBGfxr @AnnalsofSurgery
— Ville Sallinen (@villesallinen) July 9, 2021