Acesso livre
Acesso livre

Farmácia/Notícias da Indústria

[Comunicado de imprensa – ainda não publicado] Um estudo de fase 3, com mais de 10.000 participantes, mostrou que a dose de reforço com a vacina da Pfizer/BioNTech teve eficácia de 95,6% contra Covid-19; houve 5 casos de doença no grupo com dose de reforço e 109 casos no grupo-controle, sem classificação quanto à gravidade da doença.

22 Out, 2021 | 12:31h

Pfizer and BioNTech Announce Phase 3 Trial Data Showing High Efficacy of a Booster Dose of Their COVID-19 Vaccine

Comentário: Booster dose of Pfizer/BioNTech coronavirus vaccine shows 95.6% efficacy in Phase 3 trial, companies say – CNN

 

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Estudo randomizado | Mirtazapina não é melhor que placebo para tratar a agitação em pessoas com demência e possivelmente esteve associada a mortalidade aumentada (7 mortes vs. 1, diferença não estatisticamente significativa, p = 0,065).

22 Out, 2021 | 12:17h

Study of mirtazapine for agitated behaviours in dementia (SYMBAD): a randomised, double-blind, placebo-controlled trial – The Lancet

Comentário: Common antidepressant should no longer be used to treat people with dementia – University of Exeter


Vacina da Pfizer mostrou efetividade estimada de 93% contra infecção sintomática pela variante Delta do SARS-CoV-2 em adolescentes.

21 Out, 2021 | 11:37h

Effectiveness of BNT162b2 Vaccine against Delta Variant in Adolescents – New England Journal of Medicine

Conteúdo relacionado: CDC Study: Pfizer vaccine showed 93% effectiveness against Covid-19 hospitalization among children aged 12-18 years.

 

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Uma análise da mortalidade de 114.000 pessoas infectadas pelo SARS-CoV-2 na Escócia revelou que a efetividade da vacina contra morte pela variante Delta foi de 90% para a Pfizer e 91% para a AstraZeneca.

21 Out, 2021 | 11:35h

BNT162b2 and ChAdOx1 nCoV-19 Vaccine Effectiveness against Death from the Delta Variant – New England Journal of Medicine


Um estudo de caso-controle mostrou que a vacinação contra Covid-19 no início da gestação não esteve associada a risco aumentado de aborto no primeiro trimestre.

21 Out, 2021 | 11:34h

Covid-19 Vaccination during Pregnancy and First-Trimester Miscarriage – New England Journal of Medicine

Conteúdos relacionados:

Editorial: Covid-19 treatments and vaccines must be evaluated in pregnancy.

Cohort study: Vaccinated pregnant patients had 90% lower risk of severe or critical Covid-19 compared with unvaccinated pregnant patients.

Two observational studies suggest spontaneous abortion is not increased following COVID-19 mRNA vaccination during pregnancy.

Study shows high effectiveness of the Pfizer mRNA COVID-19 vaccine in pregnancy.

5 Crucial Things to Know About COVID-19 Vaccines and Pregnancy.

CDC Guidance: Pregnant people should be vaccinated against COVID-19.

ACOG and SMFM Recommend COVID-19 Vaccination for Pregnant Individuals – “ACOG encourages its members to enthusiastically recommend vaccination to their patients.”

Cohort study: Pfizer/BioNTech COVID vaccine associated with 78% lower risk of Covid-19 in pregnancy.


FDA autoriza o uso de doses de reforço das vacinas da Moderna e da Johnson & Johnson, e afirma que misturar e combinar é OK.

21 Out, 2021 | 11:29h

FDA authorizes booster doses of Moderna and Johnson & Johnson vaccines, says mix and match OK – CNN

Ver também:

FDA OKs mixing COVID vaccines; backs Moderna, J&J boosters – Associated Press

FDA OKs Moderna, J&J boosters, along with ‘mix and match’ approach – NBC News


Diretriz NCCN | Doença tromboembólica venosa associada a câncer.

21 Out, 2021 | 11:25h

Cancer-Associated Venous Thromboembolic Disease, Version 2.2021, NCCN Clinical Practice Guidelines in Oncology – Journal of the National Comprehensive Cancer Network

Conteúdos relacionados:

ASH 2021 guidelines for prevention and treatment of venous thromboembolism in patients with cancer

Review: venous and arterial thromboembolism in patients with cancer.

Systematic Review: Does testing for cancer in people with unprovoked blood clots in the legs and lungs reduce cancer- and blood clot-related death and illness?

M-A: Extended thromboprophylaxis after hospital discharge for medically ill patients with cancer – Extended thromboprophylaxis is not associated with a reduced rate of venous thromboembolic events and is associated with increased risk of hemorrhage

Systematic review: Primary prophylaxis for venous thromboembolism in ambulatory cancer patients receiving chemotherapy


O International Cannabis Toolkit (iCannToolkit): um consenso multidisciplinar de especialistas sobre os padrões mínimos para medir o uso de cannabis.

21 Out, 2021 | 11:13h

The International Cannabis Toolkit (iCannToolkit): a multidisciplinary expert consensus on minimum standards for measuring cannabis use – Addiction

Comentário: How to measure cannabis use: introducing the ‘International Cannabis Toolkit’ or iCannToolkit – The Mental Elf


Estudo randomizado | Nivolumabe vs. placebo em pacientes com mesotelioma maligno recidivante.

21 Out, 2021 | 11:10h

Nivolumab versus placebo in patients with relapsed malignant mesothelioma (CONFIRM): a multicentre, double-blind, randomised, phase 3 trial – The Lancet Oncology

 

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Estudo do CDC | Vacina da Pfizer mostrou 93% de efetividade contra internações por Covid-19 entre crianças de 12 a 18 anos.

20 Out, 2021 | 12:12h

Effectiveness of Pfizer-BioNTech mRNA Vaccination Against COVID-19 Hospitalization Among Persons Aged 12–18 Years — United States, June–September 2021 – CDC Morbidity and Mortality Weekly Report

 

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