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Farmácia/Notícias da Indústria

Incidência de miocardite/pericardite após vacinação contra COVID-19 com vacina mRNA entre crianças e jovens adultos nos EUA.

17 Out, 2022 | 13:38h

Incidence of Myocarditis/Pericarditis Following mRNA COVID-19 Vaccination Among Children and Younger Adults in the United States – Annals of Internal Medicine

Comunicado de imprensa: Incidence of myocarditis/pericarditis following mRNA COVID-19 vaccination among children, younger adults in the US – American College of Physicians

 

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Riscos e benefícios associados à continuação de anti-TNF após 24 semanas de gestação na doença inflamatória intestinal.

17 Out, 2022 | 13:02h

Benefits and Risks Associated With Continuation of Anti–Tumor Necrosis Factor After 24 Weeks of Pregnancy in Women With Inflammatory Bowel Disease – Annals of Internal Medicine (link para o resumo – $ para o texto completo)

Comunicado de imprensa: Anti-TNF continuation after 24 weeks of pregnancy beneficial to persons with IBD, does not affect neonatal outcomes – American College of Physicians

Comentário: Continuation of Anti-TNF for IBD After 24 Weeks of Pregnancy Beneficial – HealthDay

 

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M-A de rede | Eficácia comparativa de terapias de redução de lípides adicionadas a máximas doses toleradas de estatinas na redução do LDL-colesterol.

13 Set, 2022 | 11:53h

Network Meta‐Analysis of Randomized Trials Evaluating the Comparative Efficacy of Lipid‐Lowering Therapies Added to Maximally Tolerated Statins for the Reduction of Low‐Density Lipoprotein Cholesterol – Journal of the American Heart Association

 

Não adesão ao tratamento foi revelada por meio de medidas da concentração sérica de medicamentos anti-hipertensivos em 1/3 dos pacientes com hipertensão resistente previamente avaliados como aderentes ao tratamento.

13 Set, 2022 | 11:51h

Nonadherence by Serum Drug Analyses in Resistant Hypertension: 7‐Year Follow‐Up of Patients Considered Adherent by Directly Observed Therapy – Journal of the American Heart Association

 

Resumo de diretriz | Tratamento de pacientes com alergia a antibiótico suspeita ou confirmada.

12 Set, 2022 | 11:34h

Management of Patients with Suspected or Confirmed Antibiotic Allergy. Executive Summary of Guidance from the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC), the Spanish Society of Allergy and Clinical Immunology (SEAIC), the Spanish Society of Hospital Pharmacy (SEFH) and the Spanish Society of Intensive Medicine and Coronary Care Units (SEMICYUC) – Journal of Investigational Allergology and Clinical Immunology (PDF)

Conteúdos relacionados:

The prevalence of penicillin allergy labeling ranged from 0.9% to 10.2% across practices in a large pediatric cohort, raising questions regarding the validity of those labels and the unnecessary use of second-line antibiotics that may follow.

The prevalence of penicillin allergy labeling ranged from 0.9% to 10.2% across practices in a large pediatric cohort, raising questions regarding the validity of those labels and the unnecessary use of second-line antibiotics that may follow.

M-A: Most patients with allergy to Penicillin can be given Cefazolin

Systematic review: Safety and efficacy of de-labelling penicillin allergy in adults using direct oral challenge

Penicillin allergy labels increase second-line broad-spectrum antibiotic prescribing for pediatric respiratory tract infections

Podcast: A Clinical Pharmacologist’s Perspective on Penicillin Allergy

Study: Development and Validation of a Penicillin Allergy Clinical Decision Rule

Management of a surgical patient with a label of penicillin allergy: narrative review and consensus recommendations – British Journal of Anaesthesia

NICE: Double Check Patients with ‘Penicillin Allergy’ to Avoid Increased MRSA Risk

Cohort Study: Risk of Meticillin Resistant Staphylococcus Aureus and Clostridium Difficile in Patients with a Documented Penicillin Allergy

 

Perspectiva | Uso de drogas psicodélicas na depressão.

12 Set, 2022 | 11:21h

Psychedelic drugs take on depression – Nature

 

Revisão sistemática | Probióticos na prevenção de infecções agudas do trato respiratório superior.

8 Set, 2022 | 14:05h

Probiotics for preventing acute upper respiratory tract infections – Cochrane Library

 

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Estudo levanta preocupações sobre a efetividade da vacina contra a varíola dos macacos.

8 Set, 2022 | 14:03h

Study raises concerns about the effectiveness of the monkeypox vaccine – STAT

Estudo original (preprint): Low levels of monkeypox virus neutralizing antibodies after MVA-BN vaccination in healthy individuals – medRxiv

 

Revisão sistemática | Tratamento com agonistas opioides para pessoas dependentes de medicamentos opioides.

8 Set, 2022 | 13:52h

Opioid agonist treatment for people who are dependent on pharmaceutical opioids – Cochrane Library

Resumo: Opioid maintenance medicines for the treatment of dependence on opioid pain medicines – Cochrane Library

 

Revisão | Complicações cardiovasculares dos imunoterápicos para câncer.

8 Set, 2022 | 13:40h

Cardiovascular complications of immune checkpoint inhibitors for cancer – European Heart Journal

Conteúdos relacionados:

Major Adverse Cardiac Events With Immune Checkpoint Inhibitors: A Pooled Analysis of Trials Sponsored by the National Cancer Institute—Cancer Therapy Evaluation Program – Journal of Clinical Oncology

Immune Checkpoint Inhibitor Myocarditis: Pathophysiological Characteristics, Diagnosis, and Treatment – Journal of the American Heart Association

Cardiotoxicity of immune checkpoint inhibitors – ESMO Open

Cardiotoxicity from immune checkpoint inhibitors – IJC Heart & Vasculature

Cardiovascular toxicity of immune checkpoint inhibitors in cancer patients: A review when cardiology meets immuno-oncology – Journal of the Formosan Medical Association

Immune-Checkpoint Inhibitor-Induced Fulminant Myocarditis and Cardiogenic Shock – JACC: CardioOncology

 

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