Acesso livre
Acesso livre

Hematologia Geral

Diretrizes sobre doença falciforme | Prevenção secundária de AVC em crianças e adolescentes.

23 Mar, 2022 | 11:47h

Guidelines on sickle cell disease: secondary stroke prevention in children and adolescents. Associação Brasileira de Hematologia, Hemoterapia e Terapia Celular guidelines project: Associação Médica Brasileira – 2022 – Hematology, Transfusion and Cell Therapy

Conteúdo relacionado: RCT: In children with sickle cell anemia, hydroxyurea in moderate doses (20 mg/kg per day) is not better than low doses (10 mg/kg per day) for primary stroke prevention.

Debate Pró-Con | Transfusão sanguínea pré-hospitalar – deveria ser adotada para traumas em civis?

22 Mar, 2022 | 11:37h

Pro-Con Debate: Prehospital Blood Transfusion—Should It Be Adopted for Civilian Trauma? – Anesthesia & Analgesia

Infográfico: Pre-Hospital Blood Transfusion: A Pro-Con Debate – Anesthesia & Analgesia

Conteúdo relacionado: RCT: In patients with trauma-related hemorrhagic shock receiving prehospital care, there was no benefit from resuscitation with blood products compared to 0.9% sodium chloride.

Terapia genética com valoctocogene roxaparvovec para hemofilia A.

22 Mar, 2022 | 11:28h

Valoctocogene Roxaparvovec Gene Therapy for Hemophilia A – New England Journal of Medicine (link para o resumo – $ para o texto completo)

Comentários:

Valoctocogene Roxaparvovec Evaluated in Severe Hemophilia A – HealthDay

Hemophilia A Gene Therapy Reduced Bleeding Events, Need for Clotting Factors – AJMC

Diretriz | Manejo de anticoagulantes e antiplaquetários durante sangramento gastrintestinal agudo e período periendoscópico.

21 Mar, 2022 | 16:38h

American College of Gastroenterology-Canadian Association of Gastroenterology Clinical Practice Guideline: Management of Anticoagulants and Antiplatelets During Acute Gastrointestinal Bleeding and the Periendoscopic Period – Journal of the Canadian Association of Gastroenterology

 

Comentário no Twitter

 

Visão geral da ressuscitação no trauma e complicações de transfusão.

17 Mar, 2022 | 12:39h

Happy TRALIdays: An Overview of Trauma Resuscitation and Transfusion Complications – emDocs

Metanálise de estudos randomizados comparando estratégias de transfusão de hemácias intraoperatória.

14 Mar, 2022 | 14:07h

A Systematic Review and Meta-analysis of Randomized Controlled Trials Comparing Intraoperative Red Blood Cell Transfusion Strategies – Annals of Surgery

Conteúdos relacionados:

Systematic Review: Restrictive transfusion thresholds can safely decrease transfusions by 41% across a broad range of clinical contexts.

RCT: Among patients with acute MI and anemia, a restrictive transfusion strategy resulted in a noninferior rate of major cardiovascular events compared to a liberal transfusion strategy

Randomized trial: Liberal vs. restrictive transfusion thresholds in extremely low-birth-weight infants

Meta-Analysis: Effects of Restrictive vs. Liberal Transfusion Strategies on Longer-term Outcomes After Cardiac Surgery

Randomized Trial: In Patients Undergoing Cardiac Surgery, A Restrictive Transfusion Approach Does Not Increase the Risk of Acute Kidney Injury

Effects of restrictive red blood cell transfusion on the prognoses of adult patients undergoing cardiac surgery: a meta-analysis of randomized controlled trials – Critical Care

Research: Restrictive or Liberal Red-Cell Transfusion for Cardiac Surgery

Transfusion Requirements After Cardiac Surgery: The TRACS Randomized Controlled Trial – JAMA

Metanálise de estudos randomizados | Benefícios e prejuízos de anticoagulantes orais diretos e da heparina de baixo peso molecular para a tromboprofilaxia de pacientes submetidos a cirurgia não cardíaca.

10 Mar, 2022 | 15:52h

Benefits and harms of direct oral anticoagulation and low molecular weight heparin for thromboprophylaxis in patients undergoing non-cardiac surgery: systematic review and network meta-analysis of randomised trials – The BMJ

 

Comentário no Twitter

 

Perspectiva | Uma vez visto como um tratamento promissor da COVID-19, o plasma convalescente cai em desuso.

10 Mar, 2022 | 15:49h

Once Viewed as a Promising COVID-19 Treatment, Convalescent Plasma Falls Out of Favor – JAMA

Estudo randomizado | Em pacientes com choque hemorrágico relacionado a trauma recebendo cuidados pré-hospitalares, não houve benefício na ressuscitação com hemoderivados em comparação com o cloreto de sódio 0,9%.

9 Mar, 2022 | 13:49h

Resuscitation with blood products in patients with trauma-related haemorrhagic shock receiving prehospital care (RePHILL): a multicentre, open-label, randomised, controlled, phase 3 trial – The Lancet Haematology

Comentário convidado: Prehospital blood transfusion: who benefits? – The Lancet Haematology

 

Comentário no Twitter

 

Revisão sistemática | Anticoagulantes para pessoas internadas com COVID-19.

8 Mar, 2022 | 17:53h

Anticoagulants for people hospitalised with COVID‐19 – Cochrane Library

Resumo: Do blood thinners prevent people who are hospitalised with COVID-19 from developing blood clots? – Cochrane Library

Conteúdo relacionado: Anticoagulation in Patients With COVID-19: JACC Review Topic of the Week.

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