Metanálise de estudos randomizados | Benefícios e prejuízos de anticoagulantes orais diretos e da heparina de baixo peso molecular para a tromboprofilaxia de pacientes submetidos a cirurgia não cardíaca.

Benefits and harms of direct oral anticoagulation and low molecular weight heparin for thromboprophylaxis in patients undergoing non-cardiac surgery: systematic review and network meta-analysis of randomised trials – The BMJ

Comentário no Twitter

Led by Maura Marcucci, network meta-analysis of of 68 surgery #RCT's (45,445 patients; mainly #ortho) found that #DOAC's & #LMWH reduce #VTE but probably increase major bleeding to a similar extent. DOACs probably prevent symptomatic VTE more than #LMWH. https://t.co/7vrgVpfD3s pic.twitter.com/H5Fuq7p1hi

— Kari Tikkinen (@KariTikkinen) March 9, 2022