Acesso livre
Acesso livre

Endocrinologia

Diretriz preliminar da USPSTF revisa a diretriz anterior e agora recomenda contra iniciar aspirina em baixa dose como prevenção primária de doença cardiovascular (DCV) em pessoas com 60 anos de idade ou mais.

13 Out, 2021 | 13:25h

USPSTF Draft Recommendation Statement: Aspirin Use to Prevent Cardiovascular Disease – U.S. Preventive Services Task Force

Comentários:

Advice shifting on aspirin use for preventing heart attacks – Associated Press

Taking aspirin to prevent heart attack may cause more harm than good, task force says – NPR

Estudos randomizados relacionados:

Randomized Trial: Aspirin for Primary Prevention of Cardiovascular Disease

Randomized Trial: Effects of Aspirin for Primary Prevention in Persons with Diabetes

Randomized Trial: Effect of Aspirin on All-Cause Mortality in the Healthy Elderly

Metanálises relacionadas:

Meta-Analysis: Association of Aspirin Use for Primary Prevention with Cardiovascular Events and Bleeding Events

Meta-Analysis: Efficacy and Safety of Aspirin for Primary Prevention of Cardiovascular Events

Aspirin for primary prevention of cardiovascular disease: a meta-analysis with a particular focus on subgroups – BMC Medicine

Opiniões relacionadas:

Aspirin for Primary Prevention: Is This the End of the Road?

Evidence evolving on aspirin as prevention – ACP Internist

 

Comentário no Twitter

 

M-A | Suplementação de ácidos graxos ômega-3 está associada a risco aumentado de fibrilação atrial.

13 Out, 2021 | 13:17h

Effect of Long-Term Marine Omega-3 Fatty Acids Supplementation on the Risk of Atrial Fibrillation in Randomized Controlled Trials of Cardiovascular Outcomes: A Systematic Review and Meta-Analysis – Circulation (link para o resumo – $ para o texto completo)

Conteúdos relacionados:

M-A: Omega-3 fatty acids supplementation increases the risk of atrial fibrillation in patients with lipid disorders.

More data suggests no cardiovascular benefit from Omega-3 supplementation – secondary analysis of STRENGHT trial did not show an association between achieved Omega-3 fatty acid levels and major adverse cardiovascular outcomes in patients with high cardiovascular risk.

RCT: Omega-3 supplements do not reduce cardiovascular events in elderly patients after myocardial infarction

#AHA20 – Randomized trial: High-dose Omega-3 fatty acids did not reduce the risk of cardiac events in patients at high cardiovascular risk

Meta-Analysis of Randomized Trials: Little Benefit from Omega-3 Intake to Reduce Cardiovascular Disease Risk

 

Comentário no Twitter

 

Revisão | Dieta ótima para a saúde cardiovascular e planetária.

13 Out, 2021 | 13:14h

Optimal diet for cardiovascular and planetary health – Heart

Amplo estudo observacional sugere que a gastrectomia vertical pode ser mais segura se comparada ao bypass gástrico em pacientes com obesidade grave.

8 Out, 2021 | 11:43h

Comparative Safety of Sleeve Gastrectomy and Gastric Bypass Up to 5 Years After Surgery in Patients With Severe Obesity – JAMA Surgery (gratuito por tempo limitado)

Comentários:

Compared to What?—Novel Methods to Approach Randomization for Long-term Bariatric Surgery Outcomes – JAMA Surgery (gratuito por tempo limitado)

Of two common weight loss surgeries, one is safer but less effective – Michigan Medicine

Conteúdos relacionados:

Different risks and benefits leading to similar costs after sleeve gastrectomy and roux-en-y gastric bypass.

Laparoscopic roux-en-y gastric bypass vs. laparoscopic sleeve gastrectomy: 5-year outcomes of merged data from two randomized clinical trials

Randomized trial: no difference in quality of life and slightly greater weight loss with roux-en-y gastric bypass compared to laparoscopic sleeve gastrectomy at 7 years

Cohort study: comparing the 5-year diabetes outcomes of sleeve gastrectomy and gastric bypass

Cohort study: interventions and operations 5 years after bariatric surgery

Cohort study: risk of operative and nonoperative interventions after roux-en-y gastric bypass vs. vertical sleeve gastrectomy

Randomized trial: gastric bypass superior to sleeve gastrectomy for remission of type 2 diabetes

Research: laparoscopic sleeve gastrectomy vs laparoscopic roux-en-y gastric bypass

 

Comentário no Twitter

 

Diagnóstico e tratamento dos efeitos colaterais endocrinológicos dos imunoterápicos usados no tratamento do câncer.

8 Out, 2021 | 10:54h

The Diagnosis and Management of Endocrine Side Effects of Immune Checkpoint Inhibitors – Deutsches Ärzteblatt International

Conteúdo relacionado: Review: Endocrine complications of immunotherapies

COVID-19 e doença metabólica: mecanismos e abordagem clínica.

5 Out, 2021 | 11:31h

COVID-19 and metabolic disease: mechanisms and clinical management – The Lancet Diabetes & Endocrinology

Conteúdo relacionado: Review | Interplay between endocrinology, metabolism, and COVID-19 infection.

Estudo de coorte | Início de terapia com estatina está associado a risco aumentado de progressão do diabetes.

5 Out, 2021 | 11:20h

Association of Statin Therapy Initiation With Diabetes Progression: A Retrospective Matched-Cohort Study – JAMA Internal Medicine

Comentários:

Statin Therapy Initiation and Diabetes Progression – American College of Cardiology

Statin Initiation Linked to Greater Progression of Diabetes – HealthDay

Diabetes progression with initiation of statins – MedicalRessearch.com

Conteúdos relacionados:

Meta-Analysis: Medications that Reduce or Increase the Risk of New Onset Diabetes

Observational Study Points to an Increased Risk of Diabetes Among Patients Using Statins

Another Observational Study Showing Association of Statin Use with Risk of New‐Onset Diabetes Mellitus

Cohort Study: Statin Use Associated with a 38% Higher Risk of Incident Type 2 Diabetes

 

Comentário no Twitter

 

Estudo randomizado | Efeitos da dieta cetogênica por 30 dias na composição corporal, força muscular, área muscular e desempenho de jogadores de futebol semiprofissionais.

5 Out, 2021 | 11:12h

Effects of 30 days of ketogenic diet on body composition, muscle strength, muscle area, metabolism, and performance in semi-professional soccer players – Journal of the International Society of Sports Nutrition

OMS prioriza o acesso a tratamentos de diabetes e câncer na nova Lista de Medicamentos Essenciais.

4 Out, 2021 | 10:25h

Comunicado de imprensa: WHO prioritizes access to diabetes and cancer treatments in new Essential Medicines Lists – World Health Organization

Relatório: WHO model list of essential medicines – 22nd list, 2021 – World Health Organization

Comentário: For the first time, WHO committee recommends action on high-priced essential medicines – STAT

 

Comentário no Twitter (fio – clique para saber mais)

 

Relatório de consenso ADA | Tratamento do diabetes tipo 1 em adultos.

4 Out, 2021 | 10:21h

The management of type 1 diabetes in adults. A consensus report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD) – Diabetologia

Comunicado de imprensa: New comprehensive Consensus Report to manage type 1 diabetes launched by major diabetes organisations EASD and ADA – American Associatio of Diabetes

Conteúdo relacionado: Guideline: ADA 2021 Standards of Medical Care in Diabetes

 

Comentário no Twitter

 

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