Arquivos do dia: Abril 14, 2022

Diretriz preliminar da USPSTF recomenda rastreamento de ansiedade e depressão em crianças e adolescentes de 8 a 18 anos de idade.

14 Abr, 2022 | 17:54h

Diretrizes preliminares:

Screening for Anxiety in Children and Adolescents – US Preventive Services Task Force

Screening for Depression and Suicide Risk in Children and Adolescents – US Preventive Services Task Force

Comentário: USPSTF Recommends Anxiety, Depression Screening for Children – HealthDay

---

Achados do Global Burden of Disease Study 2019 | Impacto de transtornos mentais, transtornos de uso de substâncias e autolesão entre jovens na Europa, 1990-2019.

14 Abr, 2022 | 17:52h

The burden of mental disorders, substance use disorders and self-harm among young people in Europe, 1990–2019: Findings from the Global Burden of Disease Study 2019 – The Lancet Regional Health Europe

Comentário convidado: The burden of young people’s mental health conditions in Europe: No cause for complacency – The Lancet Regional Health Europe

Conteúdos relacionados:

Global, regional, and national burden of 12 mental disorders in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019.

New Global Burden of Disease analyses show depression and anxiety among the top causes of health burden worldwide, and a significant increase due to the COVID-19 pandemic.

 

Comentário no Twitter

See our new @IHME_UW analysis from on the #burden of #mentaldisorders, substance use disorders & self-harm among young people in Europe. In 2019 there were 16,983 MDs cases/100.000. In last 30 yrs YLD for eating disorders & drug use disorders increased. https://t.co/hMbHDlPuur pic.twitter.com/Rt4Iq4tpAA

— Maciej Banach (@maciejbanach) April 2, 2022

(Artigos e imagens sob licença de CC BY 4.0)

---

Estudo randomizado | Intervenção de mudança comportamental baseada em exercícios domiciliares de caminhada aumentaram a distância percorrida em testes de avaliação por adultos com doença arterial periférica.

14 Abr, 2022 | 17:50h

Effect of a Home-Based, Walking Exercise Behavior Change Intervention vs Usual Care on Walking in Adults With Peripheral Artery Disease: The MOSAIC Randomized Clinical Trial – JAMA (gratuito por tempo limitado)

 

Comentário no Twitter

In this study, among adults with peripheral artery disease, a home-based, #walking #exercise behavior change intervention, compared with usual care, increased 6-minute walking distance at 3 months. https://t.co/5ea3YOWlN0 @LindsayBearne pic.twitter.com/s06ONnki9y

— JAMA (@JAMA_current) April 12, 2022

 

---

Revisão | Diagnóstico e tratamento da hipertensão arterial pulmonar.

14 Abr, 2022 | 17:48h

Diagnosis and Treatment of Pulmonary Arterial Hypertension: A Review – JAMA (gratuito por tempo limitado)

Revisão clínica em áudio: Diagnosis and Treatment of Pulmonary Arterial Hypertension – JAMA

 

Comentário no Twitter

This review summarizes current evidence regarding diagnosis and treatment of pulmonary arterial #hypertension. https://t.co/Ebo33PD8Qq

— JAMA (@JAMA_current) April 12, 2022

 

---

Estudo randomizado por cluster | Antibioticoprofilaxia mais curta (menos de 24 horas após a cirurgia) é não inferior a um regime mais estendido (24-48 horas) após cirurgia ortopédica limpa.

14 Abr, 2022 | 17:47h

Effect of Antimicrobial Prophylaxis Duration on Health Care–Associated Infections After Clean Orthopedic Surgery: A Cluster Randomized Trial – JAMA Network Open

 

Comentário no Twitter

Cluster RCT of patients who underwent clean orthopedic surgery found shorter antimicrobial prophylaxis duration (<24h postop) was noninferior to longer duration (<48h) in preventing health care associated infections and across a range of clinical outcomes. https://t.co/FFzxNiHxet

— JAMA Network Open (@JAMANetworkOpen) April 12, 2022

 

---

Perspectiva | O conceito clássico de imunidade de rebanho pode não se aplicar à COVID-19.

14 Abr, 2022 | 17:46h

The Concept of Classical Herd Immunity May Not Apply to COVID-19 – The Journal of Infectious Diseases

Comunicado de imprensa: NIH experts discuss controlling COVID-19 in commentary on herd immunity – NIH News Releases

 

Comentário no Twitter

Co-authored by Dr. Anthony Fauci and two other @NIAIDNews'ers

"We no longer need the elusive concept of 'herd immunity' as an aspirational goal: COVID-19 control is already within our grasp."https://t.co/kvYfpsXviB https://t.co/aaiGcb3qtL pic.twitter.com/6yrcsKbUGi

— Alexander Tin (@Alexander_Tin) March 31, 2022

 

---

M-A | Inibidores de SGLT2 estão associados com risco reduzido de hiperpotassemia em pessoas com diabetes tipo 2.

14 Abr, 2022 | 17:44h

Sodium-glucose Cotransporter 2 Inhibitors and Risk of Hyperkalemia in People with Type 2 diabetes: A Meta-analysis of Individual Participant Data from Randomized Controlled Trials – Circulation

---

Estudo randomizado | Dapagliflozina não trouxe melhora significativa para o controle glicêmico de crianças e jovens adultos com diabetes tipo 2.

14 Abr, 2022 | 17:42h

Efficacy and safety of dapagliflozin in children and young adults with type 2 diabetes: a prospective, multicentre, randomised, parallel group, phase 3 study – The Lancet Diabetes & Endocrinology (link para o resumo – $ para o texto completo)

---

Revisão | Menos é mais: deprescrição de medicamentos em idosos com doença renal.

14 Abr, 2022 | 17:41h

Less is More: Deprescribing Medications in Older Adults with Kidney Disease: A Review – Kidney360

Conteúdos relacionados:

Process evaluation of implementation strategies to reduce potentially inappropriate medication prescribing in older population: A scoping review.

AGA clinical practice update on de-prescribing of proton pump inhibitors.

Development of a metric to detect and decrease low-value prescribing in older adults.

Cluster Randomized Clinical Trial: An electronic decision support system for deprescribing in hospitalized older adults was safe and led to improvements in deprescribing but did not reduce adverse drug events.

Systematic Review: Quantifying anticholinergic burden and sedative load in older adults with polypharmacy.

Deprescribing in palliative patients with cancer: a concise review of tools and guidelines.

Systematic review: Prescribing practices, patterns, and potential harms in patients receiving palliative care – “many patients receiving palliative care receive multiple medications closer to the time of death”.

A narrative review of evidence to guide deprescribing among older adults.

Polypharmacy, inappropriate prescribing, and deprescribing in older people: through a sex and gender lens.

Polypharmacy Management in Older Patients – Mayo Clinic Proceedings

Psychopharmacological Treatment in Older People: Avoiding Drug Interactions and Polypharmacy – Deutsches Ärzteblatt internationa

Eliminating Medication Overload: A National Action Plan

Deprescribing in Older Adults With Cardiovascular Disease – Journal of the American College of Cardiology

Position Statement: Reducing Inappropriate Medication Use & Polypharmacy (vários artigos e comentários sobre o tema)

---

Estudo randomizado | Terapia com realidade virtual automatizada no tratamento da evitação agorafóbica e da angústia em pacientes com psicose.

14 Abr, 2022 | 17:39h

Automated virtual reality therapy to treat agoraphobic avoidance and distress in patients with psychosis (gameChange): a multicentre, parallel-group, single-blind, randomised, controlled trial in England with mediation and moderation analyses – The Lancet Psychiatry

Comunicado de imprensa: Breakthrough success in provision of automated psychological therapy using virtual reality – University of Oxford

 

Comentário do autor no Twitter

gameChange results are out! Six sessions of automated VR therapy reduced agoraphobic avoidance and distress for patients with psychosis. People who were mainly housebound had large benefits maintained at 6mths. @OxPsychiatry @NIHRresearch @TheLancetPsych https://t.co/VE9oxsa5cf pic.twitter.com/KAvuLqHtiI

— Daniel Freeman (@ProfDFreeman) April 6, 2022

 

---