Estudo randomizado por cluster | Antibioticoprofilaxia mais curta (menos de 24 horas após a cirurgia) é não inferior a um regime mais estendido (24-48 horas) após cirurgia ortopédica limpa.

Effect of Antimicrobial Prophylaxis Duration on Health Care–Associated Infections After Clean Orthopedic Surgery: A Cluster Randomized Trial – JAMA Network Open

Comentário no Twitter

Cluster RCT of patients who underwent clean orthopedic surgery found shorter antimicrobial prophylaxis duration (<24h postop) was noninferior to longer duration (<48h) in preventing health care associated infections and across a range of clinical outcomes. https://t.co/FFzxNiHxet

— JAMA Network Open (@JAMANetworkOpen) April 12, 2022