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Arquivos do dia: Março 29, 2022

Estudo randomizado por cluster | Uma intervenção domiciliar de substituição do sal é custo-efetiva para a prevenção de AVC e melhorar a qualidade de vida.

29 Mar, 2022 | 15:17h

Cost-effectiveness of a Household Salt Substitution Intervention: Findings From 20,995 Participants of the Salt Substitute and Stroke Study (SSaSS) – Circulation

Comentário: ACC: Use of Salt Substitute to Prevent Stroke Is Cost-Saving – HealthDay

Estudo original: #ESCCongress – Cluster RCT: Among patients at increased risk for stroke, salt substitution (75% sodium chloride and 25% potassium chloride by mass) reduced the rates of stroke, major cardiovascular events, and death from any cause.

Conteúdos relacionados:

Former CDC director: Low sodium salt could save millions of lives – CNN

Is salt good for you after all? The evidence says no.

Systematic Review: Altered dietary salt intake for people with chronic kidney disease.

New WHO benchmarks help countries reduce salt intake and save lives.

RCT: Reduced-sodium added-potassium salt substitute reduces blood pressure in hypertensive patients

Potassium Enriched Salt Substitution Could Prevent a Large Number of Cardiovascular Deaths

Meta-Analysis: Effect of Reduction in Dietary Sodium on Blood Pressure Levels

Cluster Randomized Trial: Effect of Salt Substitution on Community-wide Blood Pressure and Hypertension Incidence

Estudo de coorte | Doença cardíaca e da artéria coronária são comuns em pacientes com infarto do miocárdio tipo 2.

29 Mar, 2022 | 15:15h

Coronary Artery and Cardiac Disease in Patients With Type 2 Myocardial Infarction: A Prospective Cohort Study – Circulation

Comentário: AHA News: Undiagnosed Heart Disease May Be Common in People With Heart Attacks Not Caused by Clots – HealthDay

 

Comentário no Twitter

 

Opinião | Vacinação global deve ser mais rápida.

29 Mar, 2022 | 15:14h

Global vaccination must be swifter – Nature

Miocardite e pericardite após vacinação contra COVID-19: diretriz para profissionais da saúde.

29 Mar, 2022 | 15:13h

Myocarditis and pericarditis after COVID-19 vaccination: clinical management guidance for healthcare professionals – UK Health Security Agency

Conteúdos relacionados:

Myocarditis following a third Pfizer vaccination dose in military recruits in Israel.

Myocarditis following COVID-19 BNT162b2 vaccination among adolescents in Hong Kong.

[Preprint] Post-marketing active surveillance of myocarditis and pericarditis following vaccination with COVID-19 mRNA vaccines in persons aged 12-39 years in Italy.

Myocarditis after BNT162b2 vaccination in Israeli adolescents.

Myocarditis cases reported after mRNA-Based COVID-19 vaccination in the US from December 2020 to August 2021.

A case-control study showed an increased risk of myocarditis after COVID-19 vaccination with a messenger RNA vaccine compared to an inactivated virus vaccine.

[Preprint] Risk of myocarditis following sequential COVID-19 vaccinations by age and sex.

Risks of myocarditis, pericarditis, and cardiac arrhythmias associated with COVID-19 vaccination vs. SARS-CoV-2 infection.

Case series with 139 adolescents and young adults with suspected myocarditis following mRNA vaccination showed most cases had a mild clinical course and rapid resolution of symptoms.

Heart-inflammation risk from Pfizer COVID vaccine is very low.

Large cohort study with over 2.5 million individuals showed the incidence of myocarditis after the Pfizer vaccine was 2.13 cases per 100,000 persons.

Study with over 5.1 million vaccinated individuals showed the incidence of myocarditis after the receipt of the Pfizer vaccine was low and more common after the second dose in young male recipients.

Large Observational study shows Pfizer Covid vaccine is mostly safe but is associated with increased risk of myocarditis, adenopathy, appendicitis, and herpes zoster.

Diretrizes brasileiras para o tratamento de pacientes ambulatoriais com COVID-19 suspeita ou confirmada.

29 Mar, 2022 | 15:10h

Brazilian guidelines for the treatment of outpatients with suspected or confirmed COVID-19. A joint guideline of the Brazilian Association of Emergency Medicine (ABRAMEDE), Brazilian Medical Association (AMB), Brazilian Society of Angiology and Vascular Surgery (SBACV), Brazilian Society of Geriatrics and Gerontology (SBGG), Brazilian Society of Infectious Diseases (SBI), Brazilian Society of Family and Community Medicine (SBFMC), and Brazilian Thoracic Society (SBPT) – The Brazilian Journal of Infectious Diseases

Estudo de coorte | Uso paterno de metformina antes da concepção está associado a risco aumentado de problemas congênitos nos descendentes.

29 Mar, 2022 | 15:08h

Preconception Antidiabetic Drugs in Men and Birth Defects in Offspring: A Nationwide Cohort Study – Annals of Internal Medicine (link para o resumo – $ para o texto completo)

Comentários:

Paternal metformin use associated with major birth defects if used during period of sperm development – American College of Physicians

Expert reaction to study of birth defects and diabetic men using metformin during sperm development – Science Media Centre

Metanálise de estudos randomizados | Agonistas receptores de GLP1 aumentam o risco de doenças de vias biliares e vesícula biliar (RR 1,37; IC 95%, 1,23-1,52).

29 Mar, 2022 | 15:07h

Association of Glucagon-Like Peptide-1 Receptor Agonist Use With Risk of Gallbladder and Biliary Diseases: A Systematic Review and Meta-analysis of Randomized Clinical Trials – JAMA Internal Medicine (gratuito por tempo limitado)

Commentary: GLP-1 Receptor Agonists: How Safe Are They for the Gallbladder?— Link with gallbladder, biliary diseases could be due to weight loss associated with class of drug – MedPage Today (gratuito por tempo limitado)

Impacto cumulativo de transtornos psiquiátricos e autolesão em 26 cânceres adultos.

29 Mar, 2022 | 15:05h

Cumulative burden of psychiatric disorders and self-harm across 26 adult cancers – Nature Medicine

Ver também: Suicide risk and mortality among patients with cancer – Nature Medicine (se o acesso a este link for pago, tente este)

Comentário convidado: Shining a light on the psychological burden of cancer – Nature Medicine

 

Comentário no Twitter

 

Cientistas descobrem que o impacto das mídias sociais sobre o bem-estar pode variar ao longo da adolescência.

29 Mar, 2022 | 15:03h

Comunicado de imprensa: Scientists find that the impact of social media on wellbeing varies across adolescence – University of Cambridge

Estudo original: Windows of developmental sensitivity to social media – Nature Communications

Comentários:

Negative impact of social media affects girls and boys at different ages – study – University of Oxford

Teenage social media use linked to less life-satisfaction for some – BBC

Social media may affect girls’ mental health earlier than boys’, study finds – The Guardian

Expert reaction to study on social media use and wellbeing over adolescence – Science Media Centre

Consenso multidisciplinar para o tratamento do tromboembolismo pulmonar.

29 Mar, 2022 | 14:59h

Multidisciplinary consensus for the management of pulmonary thromboembolism – Archivos de Bronconeumología

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