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Arquivos do dia: Janeiro 31, 2022

Posicionamento científico | Prevenção da insuficiência cardíaca.

31 Jan, 2022 | 09:04h

Preventing heart failure: a position paper of the Heart Failure Association in collaboration with the European Association of Preventive Cardiology

Estudos mostram que a vacinação dos pais forneceu proteção indireta das crianças contra a infecção pelo SARS-CoV-2 durante a onda da variante Delta.

31 Jan, 2022 | 09:03h

Indirect protection of children from SARS-CoV-2 infection through parental vaccination – Science

Ver também: Vaccination with BNT162b2 reduces transmission of SARS-CoV-2 to household contacts in Israel – Science

Comentário: COVID vaccine markedly cuts household transmission, studies show – CIDRAP

 

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Análise observacional na Lombardia, na Itália, mostrou uma redução gradual na proteção contra os desfechos clínicos de SARS-CoV-2 após a segunda dose da vacina.

31 Jan, 2022 | 09:02h

Persistence of protection against SARS-CoV-2 clinical outcomes up to 9 months since vaccine completion: a retrospective observational analysis in Lombardy, Italy – The Lancet Infectious Diseases

Comentário: COVID-19 vaccine: what are we doing and what should we do? – The Lancet Infectious Diseases

Um estudo de coorte de amplitude nacional na Dinamarca mostrou que a “long Covid” em crianças é rara e de curta duração.

31 Jan, 2022 | 09:00h

Long COVID symptoms and duration in SARS-CoV-2 positive children — a nationwide cohort study – European Journal of Pediatrics

Conteúdos relacionados:

Editorial | Long covid in children and adolescents – “Risk appears low, but many questions remain”.

M-A: Persistent symptoms following SARS-CoV-2 infection among children and young people – “Higher study quality was associated with lower prevalence of all symptoms, except loss of smell and cognitive symptoms”.

Review: Long COVID symptoms in children rarely persist beyond three months.

Cohort study: long term follow-up showed most patients with post–COVID-19 Multisystem Inflammatory Syndrome in Children had good outcomes with no significant medium- or long-term sequelae.

Do kids get long COVID? And how often? A pediatrician looks at the data – Children also get Long Covid, but much less often than adults.

Illness duration and symptom profile in symptomatic school-aged children tested for SARS-CoV-2 – “Only 25 (1.8%) of 1379 children experienced symptoms for at least 56 days.”

Long-term Symptoms After SARS-CoV-2 Infection in Children and Adolescents – “This study found a low prevalence of symptoms compatible with long COVID in a randomly selected cohort of children assessed 6 months after serologic testing”.

Study shows low incidence of post-acute COVID-19 symptoms (“Long Covid”) in children after mild disease

 

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Apesar da contínua disseminação da Ômicron, alguns países europeus decidiram suspender os protocolos de restrições para Covid-19.

31 Jan, 2022 | 08:58h

England lifts COVID restrictions as omicron threat recedes – Associated Press

Denmark confirms plan to lift Covid-19 restrictions on February 1st – The Local dk

Netherlands lifts toughest Covid curbs with Denmark and France set to follow – The Guardian

Denmark will lift nearly ALL Covid restrictions within days and return to ‘life as we knew it before corona’ after vaccine programme proved a ‘super-weapon’ – despite soaring cases – Daily Mail

 

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FDA interrompe o uso de anticorpos monoclonais que não funcionam contra a Ômicron.

31 Jan, 2022 | 08:56h

FDA halts use of antibody drugs that don’t work vs. omicron – Associated Press

Conteúdo relacionado: Lab study shows new antiviral pills maintain efficacy against Omicron, but antibody drugs are substantially less effective.

Miocardite após vacinação de adolescentes com BNT162b2 em Israel.

31 Jan, 2022 | 08:55h

Myocarditis after BNT162b2 Vaccination in Israeli Adolescents – New England Journal of Medicine

Conteúdos relacionados:

Myocarditis cases reported after mRNA-Based COVID-19 vaccination in the US from December 2020 to August 2021.

A case-control study showed an increased risk of myocarditis after COVID-19 vaccination with a messenger RNA vaccine compared to an inactivated virus vaccine.

[Preprint] Risk of myocarditis following sequential COVID-19 vaccinations by age and sex.

Risks of myocarditis, pericarditis, and cardiac arrhythmias associated with COVID-19 vaccination vs. SARS-CoV-2 infection.

Case series with 139 adolescents and young adults with suspected myocarditis following mRNA vaccination showed most cases had a mild clinical course and rapid resolution of symptoms.

Heart-inflammation risk from Pfizer COVID vaccine is very low.

Large cohort study with over 2.5 million individuals showed the incidence of myocarditis after the Pfizer vaccine was 2.13 cases per 100,000 persons.

Study with over 5.1 million vaccinated individuals showed the incidence of myocarditis after the receipt of the Pfizer vaccine was low and more common after the second dose in young male recipients.

Large Observational study shows Pfizer Covid vaccine is mostly safe but is associated with increased risk of myocarditis, adenopathy, appendicitis, and herpes zoster.

 

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Robô realiza a primeira cirurgia laparoscópica em um porco sem auxílio humano.

31 Jan, 2022 | 08:52h

Autonomous robotic laparoscopic surgery for intestinal anastomosis – Science Robotics

Comentários:

Robot performs first laparoscopic surgery without human help – Johns Hopkins University

In a First, a Robot Performs Laparoscopic Surgery on Pig Without Human Help – HealthDay

Estudo randomizado | Suplementação de vitamina D para idosos (média de idade: 67 anos) por 5 anos reduziu o risco de doenças autoimunes em 22%. O risco absoluto no grupo em tratamento foi de 0,95% vs. 1,19% no grupo placebo.

31 Jan, 2022 | 08:51h

Vitamin D and marine omega 3 fatty acid supplementation and incident autoimmune disease: VITAL randomized controlled trial – The BMJ

Comentário: Vitamin D and fish oil supplements may help prevent autoimmune disease, study says – CNN

Conteúdos relacionados:

RCT: Oral Vitamin D supplementation (60.000 IU per month) did not reduce mortality in patients 60 years or older (unscreened individuals in Australia, many without insufficiency, average 30ng/mL). Exploratory analyses pointed towards an increased risk of death from cancer.

RCT: Vitamin D supplementation is not beneficial for the prevention of cardiovascular disease and cancer.

USPSTF Draft Statement: Insufficient evidence to recommend multivitamin supplements for the prevention of CVD or cancer. The statement also recommends against the use of beta-carotene (increases risk of CVD mortality and lung cancer) or vitamin E (clear evidence of no benefit)

USPSTF Statement: Insufficient evidence to recommend Vitamin D deficiency screening

Vitamin D, calcium, other vitamins, and supplements do not prevent cardiovascular diseases

Revisão sistemática | Dietas com baixo carboidrato vs. dietas com carboidrato equilibrado para redução de peso e de risco cardiovascular.

31 Jan, 2022 | 08:49h

Low‐carbohydrate versus balanced‐carbohydrate diets for reducing weight and cardiovascular risk – Cochrane Library

Resumo: Low-carbohydrate diets or balanced-carbohydrate diets: which works better for weight loss and heart disease risks? – Cochrane Library

Comentário: Featured review: Low-carbohydrate versus balanced-carbohydrate diets for reducing weight and cardiovascular risk – Cochrane Library

 

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