Arquivos do dia: Novembro 15, 2021
Estudo randomizado fase 4 | Administração de vacinas contra COVID-19 (AstraZeneca ou Pfizer) concomitantemente às vacinas contra influenza sazonal em adultos é segura e preserva a resposta imune de ambas as vacinas.
15 Nov, 2021 | 14:10hAmplo estudo populacional mostra que infecção prévia por SARS-CoV-2 reduz o risco de infecção após vacina de mRNA.
15 Nov, 2021 | 14:08hComentários:
Vaccine plus previous infection may offer enhanced COVID-19 protection – CIDRAP
Comentário no Twitter
Study found prior #SARSCoV2 infection was associated with lower risk for breakthrough infection among persons receiving the SARS-CoV-2 mRNA vaccines; however, the observational study design precludes direct comparison of infection risk btwn the 2 vaccines https://t.co/1RLuKSGPjy
— JAMA (@JAMA_current) November 1, 2021
Estudo populacional no Catar mostrou que a efetividade contra doença grave, crítica ou fatal induzida pela variante Delta do SARS-CoV-2 foi de 93,4% para a vacina da Pfizer e de 96,1% para a vacina da Moderna.
15 Nov, 2021 | 14:06h
Comentário no Twitter
A study in @NatureMedicine shows that mRNA COVID-19 vaccines are highly effective at preventing severe outcomes and death caused by the SARS-CoV-2 Delta variant in Qatar despite substantially lower effectiveness at blocking infection. https://t.co/V09Ma583fy pic.twitter.com/QG2HaDsrCo
— Nature Portfolio (@NaturePortfolio) November 4, 2021
[Preprint] Risco de COVID-19 grave é raro entre pessoas com vacinação plena na Inglaterra.
15 Nov, 2021 | 14:01hComentário: Risk of severe COVID-19 is rare among fully vaccinated individuals in England – News Medical
Estudo original: Describing the population experiencing COVID-19 vaccine breakthrough following second vaccination in England: A cohort study from OpenSAFELY – medRxiv
Editorial | COVID está conturbando carreiras científicas pelo mundo.
15 Nov, 2021 | 13:59hCOVID is disrupting scientific careers around the world – Nature
Ver também:
Scientists count the career costs of COVID – Nature
Potentially long-lasting effects of the pandemic on scientists – Nature
O que influencia as respostas das pessoas às mensagens de saúde pública para o controle de riscos e prevenção de doenças infecciosas? Uma breve revisão sistemática das evidências e recomendações.
15 Nov, 2021 | 13:57h
Comentário no Twitter
COVID-19 messages should:
1) be developed with communities
2) address uncertainty immediately + with transparency
3) focus on unifying messages from sources
4) frame messages aimed at increasing understanding, social responsibility + ind control https://t.co/faxtAgngAI— Caroline Tomes MFPH (@carotomes) November 12, 2021
De acordo com estudo, vacinas contra SARS-CoV-2 são seguras e imunogênicas na maioria das pessoas com câncer.
15 Nov, 2021 | 13:56hComunicado de imprensa: SARS-CoV-2 vaccines are safe and immunogenic in most people with cancer, according to study – Harvard Medical School
Estudo original: Immunogenicity and Reactogenicity of SARS-CoV-2 Vaccines in Patients With Cancer: The CANVAX Cohort Study – Journal of Clinical Oncology
Comentário do autor no Twitter (fio – clique para saber mais)
The CANVAX study is out in @JCO_ASCO! https://t.co/WKrU6dQIEB
Grateful to >1000 CANVAX participants, study leads ( @JustinGainor, @MGHPathology, @BalazsLab) and so many co-authors incl. @arthur_kim_ID, @KimberlyBlumen1, @joanhowMD, @dradityabardia
Much more to come!— Vivek Naranbhai, MD, PhD, DPhil (@vivek_naranbhai) November 10, 2021
#AHA21 – Estudo randomizado | Entre crianças e adolescentes submetidos a rastreamento ecocardiográfico e diagnosticados com doença cardíaca reumática latente, antibioticoprofilaxia secundária com penicilina G benzatina por 2 anos foi associada com redução da progressão ecocardiográfica (0,8 vs, 8,2% no grupo controle).
15 Nov, 2021 | 13:53hSecondary Antibiotic Prophylaxis for Latent Rheumatic Heart Disease – New England Journal of Medicine (link para o resumo – $ para o texto completo)
Comentários:
Secondary Antibiotic Prophylaxis for Latent Rheumatic Heart Disease – American College of Cardiology
Comentários no Twitter
One of most important studies ever Rheumatic Heart Disease @NEJM https://t.co/U8FuNHLqCJ RCT evidence 2ry prophylaxis reduces progression latent RhD pic.twitter.com/UycTElr7QM
— Michael Marks (@dr_michaelmarks) November 13, 2021
Penicillin slowed the devastating impact of rheumatic heart disease among children in Uganda. Findings of a large-scale, randomized controlled trial were completed in Uganda. Group A strep underlies rheumatic heart disease. New England Journal of Medicine https://t.co/1PKFJ12FvC
— delthia ricks 🔬 (@DelthiaRicks) November 13, 2021
#AHA21 – Estudo randomizado | Em pacientes assintomáticos com estenose aórtica grave, cirurgia precoce melhorou os desfechos em comparação ao tratamento conservador.
15 Nov, 2021 | 13:51hAortic Valve ReplAcemenT versus Conservative Treatment in Asymptomatic SeveRe Aortic Stenosis: The AVATAR Trial – Circulation (gratuito por tempo limitado)
Comunicado de imprensa: Surgery to replace heart valve beneficial even with no symptoms of severe aortic stenosis – American Heart Association
Comentários:
AVATAR Supports Early SAVR in Asymptomatic Severe AS Patients – TCTMD
Estudo relacionado: #AHA19 – Randomized Trial: Early Surgery Improves Outcomes in Asymptomatic Patients with Very Severe Aortic Stenosis
Comentário no Twitter
#OriginalResearch SimPub#AHA21: The #AVATAR RCT of 157 patients with asymptomatic severe #AS and normal LVEF found that early #SAVR associated w/reduced composite outcome of death, MI, stroke or HF hospitalization compared to mgmt. https://t.co/SdMiWHOPnp #AHAJournals pic.twitter.com/jCcWVZfzse
— Circulation (@CircAHA) November 13, 2021
#AHA21 – Estudo randomizado | Reparo tricúspide concomitante em pacientes submetidos a cirurgia por regurgitação mitral degenerativa reduziu a progressão da regurgitação tricúspide, mas aumentou a necessidade de implante de marca-passo permanente.
15 Nov, 2021 | 13:49hConcomitant Tricuspid Repair in Patients with Degenerative Mitral Regurgitation – New England Journal of Medicine (link para o resumo – $ para o texto completo)
Comentários:
Tricuspid Repair During Mitral Surgery Slows Disease Progression at 2 Years – TCTMD
CTCR-MVS: Concomitant Tricuspid Repair in Patients With MR – American College of Cardiology