#AHA21 – Estudo randomizado | Entre crianças e adolescentes submetidos a rastreamento ecocardiográfico e diagnosticados com doença cardíaca reumática latente, antibioticoprofilaxia secundária com penicilina G benzatina por 2 anos foi associada com redução da progressão ecocardiográfica (0,8 vs, 8,2% no grupo controle).

Secondary Antibiotic Prophylaxis for Latent Rheumatic Heart Disease – New England Journal of Medicine (link para o resumo – $ para o texto completo)

Comentários:

Penicillin significantly reduces rheumatic heart disease progression in children – Murdoch Children’s Research Institute

Penicillin slows devastating impacts of rheumatic heart disease in children from Uganda – Children’s National Hospital

Secondary Antibiotic Prophylaxis for Latent Rheumatic Heart Disease – American College of Cardiology

Comentários no Twitter

One of most important studies ever Rheumatic Heart Disease @NEJM https://t.co/U8FuNHLqCJ RCT evidence 2ry prophylaxis reduces progression latent RhD pic.twitter.com/UycTElr7QM

— Michael Marks (@dr_michaelmarks) November 13, 2021

Penicillin slowed the devastating impact of rheumatic heart disease among children in Uganda. Findings of a large-scale, randomized controlled trial were completed in Uganda. Group A strep underlies rheumatic heart disease. New England Journal of Medicine https://t.co/1PKFJ12FvC

— delthia ricks 🔬 (@DelthiaRicks) November 13, 2021