Acesso livre
Acesso livre

Arquivos do dia: Outubro 25, 2021

Revisão | A infecção por SARS-CoV-2 ou a vacinação levam a uma imunidade duradoura?

25 Out, 2021 | 13:09h

Does infection with or vaccination against SARS-CoV-2 lead to lasting immunity? – The Lancet Respiratory Medicine

 

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Opinião | COVID ESTEROIDE-2: dobro de esteroide, dobro de diversão? – “Dexametasona na dose de 6 mg/dia isoladamente parece ser subótima para a maioria dos pacientes com pneumonia por COVID. Já na dose de 12 mg/dia parece fornecer uma imunomodulação de intensidade razoável.”

25 Out, 2021 | 13:08h

COVID STEROID-2: Double the steroid, double the fun? – PulmCrit

Estudo original: RCT: In adults with Covid-19 and severe hypoxemia, 12 mg vs. 6 mg of Dexamethasone did not result in a statistically significant difference in the number of days alive without life support.

 

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Revisão | Envolvimento cardíaco nas implicações de longo prazo da COVID-19.

25 Out, 2021 | 13:06h

Cardiac involvement in the long-term implications of COVID-19 – Nature Reviews Cardiology

Vacina da AstraZeneca não se associou a taxas reduzidas de fertilidade nem a desfechos adversos ao nascimento.

25 Out, 2021 | 13:05h

Fertility rates and birth outcomes after ChAdOx1 nCoV-19 (AZD1222) vaccination – The Lancet

Conteúdos relacionados:

A case-controlled study showed Covid-19 vaccination during early pregnancy was not associated with increased risk of first-trimester miscarriage.

Editorial: Covid-19 treatments and vaccines must be evaluated in pregnancy.

Cohort study: Vaccinated pregnant patients had 90% lower risk of severe or critical Covid-19 compared with unvaccinated pregnant patients.

Two observational studies suggest spontaneous abortion is not increased following COVID-19 mRNA vaccination during pregnancy.

Study shows high effectiveness of the Pfizer mRNA COVID-19 vaccine in pregnancy.

5 Crucial Things to Know About COVID-19 Vaccines and Pregnancy.

CDC Guidance: Pregnant people should be vaccinated against COVID-19.

ACOG and SMFM Recommend COVID-19 Vaccination for Pregnant Individuals – “ACOG encourages its members to enthusiastically recommend vaccination to their patients.”

Cohort study: Pfizer/BioNTech COVID vaccine associated with 78% lower risk of Covid-19 in pregnancy.

 

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Como identificar quando a Covid-19 deixará de ser “pandêmica” para se tornar “endêmica”.

25 Out, 2021 | 13:03h

How you’ll know when Covid-19 has gone from “pandemic” to “endemic” – Vox

Metade das doses, um terço das doses, doses de criança: a entrega da vacina contra Covid chega a outro nível de dificuldade.

25 Out, 2021 | 13:02h

Half doses, third doses, kids’ doses: Covid vaccine delivery goes next-level difficult – STAT

Coronavírus: moradores da China começam a receber as doses de reforço da vacina.

25 Out, 2021 | 13:01h

Coronavirus: Chinese residents start receiving vaccine boosters – South China Morning Post

Orientação provisória de 2021 para prestadores de serviços de saúde sobre suporte cardíaco básico e avançado em adultos, crianças e recém-nascidos com COVID-19 suspeita ou confirmada.

25 Out, 2021 | 13:00h

2021 Interim Guidance to Health Care Providers for Basic and Advanced Cardiac Life Support in Adults, Children, and Neonates With Suspected or Confirmed COVID-19 – Circulation: Cardiovascular Quality and Outcomes

Comentário: CPR on a COVID Patient: Not a Moment to Waste Looking for PPE: Updated AHA guidance says resuscitation should not be delayed by mask availability – MedPage Today (necessário cadastro gratuito)

 

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Diretriz | Estratégias de transfusão de sangue no sangramento de adultos criticamente doentes.

25 Out, 2021 | 12:58h

Transfusion strategies in bleeding critically ill adults: a clinical practice guideline from the European Society of Intensive Care Medicine – Intensive Care Medicine

 

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Estudo randomizado | Em sobreviventes em coma de parada cardíaca fora do hospital, não houve diferença na mortalidade ou nos desfechos neurológicos com hipotermia terapêutica leve (temperatura-alvo de 34 °C) ou moderada (temperatura-alvo de 31 °C).

25 Out, 2021 | 12:57h

Effect of Moderate vs Mild Therapeutic Hypothermia on Mortality and Neurologic Outcomes in Comatose Survivors of Out-of-Hospital Cardiac Arrest: The CAPITAL CHILL Randomized Clinical Trial – JAMA (gratuito por tempo limitado)

Conteúdos relacionados:

Cooling After Cardiac Arrest – The Sclerosis of Therapeutic Fashion – “The story of how an ineffective therapy persisted for decades”

RCT: In patients with coma after out-of-hospital cardiac arrest, targeted hypothermia did not improve outcomes.

Study commentary: a history of hypothermia for cardiac arrest, 2002-2021 (RIP).

M-A: Targeted temperature management following out-of-hospital cardiac arrest – “Routine use of moderate or deep hypothermia in comatose survivors of OHCA may potentially be associated with more harm than benefit”.

 

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