Arquivos do dia: Outubro 22, 2021
[Comunicado de imprensa – ainda não publicado] Um estudo de fase 3, com mais de 10.000 participantes, mostrou que a dose de reforço com a vacina da Pfizer/BioNTech teve eficácia de 95,6% contra Covid-19; houve 5 casos de doença no grupo com dose de reforço e 109 casos no grupo-controle, sem classificação quanto à gravidade da doença.
22 Out, 2021 | 12:31h
Comentários no Twitter
This will presumably mean everyone gets boosters early next year. That’s great, because they do work. Except it’s likely to be boosters for rich countries at the expense of primary vaccination for poorer countries. You won’t stop the pandemic when half the world is unvaccinated https://t.co/F31DMSI2zf
— Niall Conroy (@NICU_doc_salone) October 21, 2021
The 1st randomized trial of a booster (3rd) shot in 10,000 people, placebo-controlled, shows 95.6% efficacy, with 5 cases (Pfizer vaccine) vs 109 in placebo group, Delta variant, broad benefit across age groups https://t.co/TQpF35d8Jk pic.twitter.com/3RkqvXNfsU
— Eric Topol (@EricTopol) October 21, 2021
Estudo randomizado | Em adultos com Covid-19 e hipoxemia grave, 12 mg vs. 6 mg de dexametasona não resultaram em diferença estatisticamente significativa no número de dias sem terapias de suporte à vida.
22 Out, 2021 | 12:29hEditorial: Glucocorticoid Dose in COVID-19: Lessons for Clinical Trials During a Pandemic – JAMA
Comentário no Twitter
In a randomized trial of patients with #COVID19 and severe hypoxemia, compared with 6 mg of dexamethasone, 12 mg of dexamethasone did not statistically significantly reduce the number of days alive without life support at 28 days https://t.co/BMgLTel4aU pic.twitter.com/WKwI8xCUYO
— JAMA (@JAMA_current) October 21, 2021
Perspectiva | A ciência imperfeita dos testes de anticorpos para imunidade contra SARS-CoV-2.
22 Out, 2021 | 12:28hThe Flawed Science of Antibody Testing for SARS-CoV-2 Immunity – JAMA
OMS estima que entre 80.000 e 180.000 profissionais da saúde podem ter morrido de Covid-19.
22 Out, 2021 | 12:25hComunicado de imprensa: WHO and partners call for action to better protect health and care workers from COVID-19 – World Health Organization
Diretriz OMS: joint statement on WHO’s estimates of health and care worker deaths due to covid-19
Comentários:
WHO calls for health worker protection against COVID-19 – CIDRAP
Covid may have killed up to 180,000 health workers globally, WHO says – The Guardian
Comentário no Twitter
.@WHO estimates 115,000 health workers have died from #Covid19. Huge, tragic loss.
And while some health workers in the US are QUITTING jobs because they don't want to be vaccinated, many HCWs around the world are still waiting for vaccine. Unconscionable. https://t.co/z4u9XSX2Wj— Helen Branswell (@HelenBranswell) October 21, 2021
Apartheid vacinal: este não é o caminho para acabar com a pandemia.
22 Out, 2021 | 12:23hVaccine apartheid: This is not the way to end the pandemic – Journal of Paediatrics and Child Health
Comentário no Twitter
Vaccine apartheid is devastating, especially for children@VSLanziotti @yoncabulutmd @surf4children @sgdambrauskas call for everyone to advocate for vaccine equity https://t.co/jzJd9kwcCi pic.twitter.com/0hEPk8B4xv
— Madhu Pai, MD, PhD (@paimadhu) October 21, 2021
M-A | Fatores de risco para um prognóstico ruim em crianças e adolescentes com COVID-19.
22 Out, 2021 | 12:22hOpinião | A política está desordenando um debate crucial sobre a imunidade obtida ao se recuperar da Covid-19.
22 Out, 2021 | 12:21hEstudo randomizado por cluster | Aumentar as fontes dietéticas de cálcio e proteína (adicionando leite, iogurte e queijo) reduziu as fraturas de quadril e quedas em idosos em casas de repouso.
22 Out, 2021 | 12:19hComunicado de imprensa: Increasing dairy intake reduces falls and fractures among older care home residents – British Medical Journal
Comentário no Twitter
Increasing intake of foods rich in calcium and protein such as milk, yoghurt, and cheese, reduces falls and fractures in older adults living in residential care, finds a randomised controlled trial published @bmj_latest today https://t.co/QzozG4Odjb
— BMJ (@bmj_company) October 21, 2021
Estudo randomizado | Mirtazapina não é melhor que placebo para tratar a agitação em pessoas com demência e possivelmente esteve associada a mortalidade aumentada (7 mortes vs. 1, diferença não estatisticamente significativa, p = 0,065).
22 Out, 2021 | 12:17hComentário: Common antidepressant should no longer be used to treat people with dementia – University of Exeter