Vacinas
Dois estudos observacionais sugerem que não há aumento nas taxas de aborto espontâneo depois da vacinação contra COVID-19 com vacina de mRNA durante a gestação.
12 Set, 2021 | 21:01hEstudo 1: Spontaneous Abortion Following COVID-19 Vaccination During Pregnancy – JAMA
Estudo 2: Receipt of mRNA Covid-19 Vaccines and Risk of Spontaneous Abortion – New England Journal of Medicine
Comentário no Twitter
📣 NO LINK BETWEEN MISCARRIAGE & COVID VACCINATION
This @JAMA_current study examined 105446 pregnancies, including 13160 miscarriages
Women with pregnancies ending in miscarriage were NOT more likely to have had 💉 in prior 28 days than those that didnthttps://t.co/7cFELq1oPM
— Ilan Schwartz MD PhD (@GermHunterMD) September 8, 2021
OMS faz apelo para que países adiem as doses de reforços contra COVID-19 até 2022 para priorizar a vacinação das populações sob maior risco ao redor do mundo e que ainda não receberam nem a primeira dose de vacina.
12 Set, 2021 | 20:58hVer também:
WHO chief urges halt to booster shots for rest of the year – Associated Press
WHO extends moratorium on booster COVID vaccine doses – CIDRAP
AstraZeneca encabeça o alerta contra a corrida por doses de reforço – “Dar a terceira dose aos mais vulneráveis, que talvez não tenham feito uma resposta imunológica completa com as duas primeiras doses, é ‘sensato’, mas qualquer decisão sobre dar a terceira dose ‘para grande parcela da população’ e ampliar a proteção obtida pelas duas primeiras doses deve ser baseada em dados clínicos.”
12 Set, 2021 | 20:57hAstraZeneca bosses warn against rush for boosters – BBC
Comentário no Twitter (fio – clique para saber mais)
"Moving too quickly to boost across the entire adult population will deprive us of these insights, leaving this important decision to rest on limited data," Mr Soriot and Sir Mene write.https://t.co/xTAk7yyu5G
— The Sharing Scientist (@ScienceShared) September 8, 2021
[Preprint] Estudo randomizado | Reforço vacinal com vacina heteróloga vs. homóloga em pacientes imunossuprimidos sem soroconversão de anticorpo contra SARS-CoV-2 após vacinação primária com vacina de mRNA.
12 Set, 2021 | 20:55h
Comentário no Twitter (fio – clique para saber mais)
Results of 60-person randomized trial of 3rd shot of mRNA or AZ vax in people on rituximab who didn't seroconvert after BNT-Pfizer (most) or Moderna vax. Found dose 3 reduced those with no humoral or cellular response from 31% to 6% …1/2 https://t.co/HIjeDaFy7w Preprint #IC
— Hilda Bastian, PhD (@hildabast) September 8, 2021
Equilíbrio entre incentivos e incentivos contrários à vacinação numa pandemia.
12 Set, 2021 | 20:51hBalancing incentives and disincentives for vaccination in a pandemic – Nature Medicine
Conteúdo relacionado: Opinion | COVID vaccines: we need to find out which incentives actually work – the author argues that policies to promote vaccine uptake should be tested in randomized clinical trials.
Estudo mostra alta efetividade da vacina de mRNA da Pfizer contra a COVID-19 na gestação.
8 Set, 2021 | 15:22hEffectiveness of the BNT162b2 mRNA COVID-19 vaccine in pregnancy – Nature Medicine
Comentários no Twitter
NEW: Estimated vaccine effectiveness in #pregnancy from 7 through to 56 d after second dose was 96% (95% CI; 89–100%) for any documented infection, 97% (91–100%) for infections with documented symptoms & 89% (43–100%) for #COVID19-related hospitalization. https://t.co/bm950wUWGL
— All Source Pregnancy (@PregnancyAll) September 7, 2021
The Pfizer-BioNTech mRNA COVID-19 vaccine was estimated to have high vaccine effectiveness in pregnant women, which is similar to the effectiveness estimated in the general population, according to a @NatureMedicine paper. https://t.co/oz5zn7zNdq pic.twitter.com/9IP5ocxzXs
— Nature Portfolio (@NaturePortfolio) September 7, 2021
Chile autoriza o uso da vacina da Sinovac para crianças de 6 anos de idade ou mais.
8 Set, 2021 | 15:19hChile authorizes Sinovac vaccine for kids of 6 and older – Associated Press
Novas recomendações da AAP sobre gripe autorizam que seja coadministrada com a vacina contra COVID-19.
8 Set, 2021 | 15:16hComunicado de imprensa: AAP flu recommendations allow for coadministration with COVID-19 vaccine – American Academy of Pediatrics
Relatório técnico: Recommendations for Prevention and Control of Influenza in Children, 2021–2022 – American Academy of Pediatrics
Conteúdo relacionado: New CDC Guidance says influenza and Covid vaccines can be given together – “COVID-19 vaccines and other vaccines may now be administered without regard to timing”
Comentário no Twitter
The 2021-’22 @AmerAcadPeds flu policy emphasizes the importance of flu vaccination during the SARS-CoV-2 pandemic, allows for coadministration with COVID-19 vaccine. https://t.co/usLaO276Ku pic.twitter.com/EaL5vocxMm
— AAP News (@AAPNews) September 7, 2021
Intervalos maiores entre as doses e doses de reforço da vacina da AstraZeneca estão associados com aumento da imunogenicidade.
7 Set, 2021 | 22:13hComentário convidado: Longer intervals and extra doses of ChAdOx1 nCoV-19 vaccine
Comentários no Twitter
(fio – clique para saber mais)
Substudy suggests extended interval (up to 45 wks) before 2nd dose of ChAdOx1 nCoV-19 leads to increased antibody titres, offering more flexibility in vaccine schedules.
Extended interval before 3rd dose resulted in further increase in immune responses. https://t.co/J3xOwSSYMN pic.twitter.com/8GotDI4ctS
— The Lancet (@TheLancet) September 2, 2021
(fio – clique para saber mais)
New @TheLancet
The heightened immune response to longer spacing @AstraZeneca 1st -> 2nd vaccine doses and the response 3rd booster dose, with high neutralizing antibodies and T cellshttps://t.co/A2UcPVIFYP pic.twitter.com/zfYaW0T8Yf— Eric Topol (@EricTopol) September 1, 2021