Acesso livre
Acesso livre

Terapia Intensiva

Revisão sistemática | Limiares restritivos de transfusão podem reduzir as transfusões de forma segura em até 41% em uma ampla variedade de contextos clínicos.

17 Jan, 2022 | 13:01h

Transfusion thresholds for guiding red blood cell transfusion – Cochrane Library

Resumo: Is it safe to use lower blood counts (haemoglobin levels) as a trigger for blood transfusion in order to give fewer blood transfusions? – Cochrane Library

Conteúdos relacionados:

RCT: Among patients with acute MI and anemia, a restrictive transfusion strategy resulted in a noninferior rate of major cardiovascular events compared to a liberal transfusion strategy

Randomized trial: Liberal vs. restrictive transfusion thresholds in extremely low-birth-weight infants

Meta-Analysis: Effects of Restrictive vs. Liberal Transfusion Strategies on Longer-term Outcomes After Cardiac Surgery

Randomized Trial: In Patients Undergoing Cardiac Surgery, A Restrictive Transfusion Approach Does Not Increase the Risk of Acute Kidney Injury

Effects of restrictive red blood cell transfusion on the prognoses of adult patients undergoing cardiac surgery: a meta-analysis of randomized controlled trials – Critical Care

Research: Restrictive or Liberal Red-Cell Transfusion for Cardiac Surgery

Transfusion Requirements After Cardiac Surgery: The TRACS Randomized Controlled Trial – JAMA

 

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Outro estudo mostrou que as terapias com anticorpos monoclonais neutralizantes não são eficazes quando administradas depois de o paciente já estar internado.

13 Jan, 2022 | 21:13h

Efficacy and safety of two neutralising monoclonal antibody therapies, sotrovimab and BRII-196 plus BRII-198, for adults hospitalised with COVID-19 (TICO): a randomised controlled trial – The Lancet Infectious Diseases

Comentário convidado: Time to knock monoclonal antibodies off the platform for patients hospitalised with COVID-19

Diretriz do Painel sobre Diretrizes de Tratamento da COVID-19 sobre anticoagulação em pacientes internados com COVID-19 – Na ausência de contraindicações, usar anticoagulação em dose terapêutica com heparina de baixo peso molecular para pacientes internados, mas não em UTI, que apresentem D-dímero acima do limite superior normal.

13 Jan, 2022 | 12:14h

The COVID-19 Treatment Guidelines Panel’s Statement on Anticoagulation in Hospitalized Patients With COVID-19 – NIH COVID-19 Treatment Guidelines

Diretriz alemã | Oxigenoterapia no cuidado agudo de pacientes adultos.

13 Jan, 2022 | 12:00h

German S3 Guideline: Oxygen Therapy in the Acute Care of Adult Patients – Respiration

Revisão | Tratamento da coagulopatia em pacientes hemorrágicos.

13 Jan, 2022 | 11:37h

Management of Coagulopathy in Bleeding Patients – Journal of Clinical Medicine

Resumo de diretrizes de prática clínica | Medicamentos recomendados para pacientes adultos com COVID-19.

12 Jan, 2022 | 13:03h

Clinical Practice Guideline Summary: Recommended Drugs and Biologics in Adult Patients with COVID-19 – Covid Advisory for Ontario

 

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Diretriz clínica | Insuficiência hepática crônica agudizada.

12 Jan, 2022 | 12:58h

Acute-on-Chronic Liver Failure Clinical Guidelines – American Journal of Gastroenterology

Conteúdo relacionado: Guidelines for the Management of Adult Acute and Acute-on-Chronic Liver Failure in the ICU

 

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Suplemento | Tratamento perioperatório e terapia intensiva para o cérebro – Evidências atuais.

12 Jan, 2022 | 12:50h

Página principal: Special Issue:Peri‐operative and critical care management of the brain ‐ current evidence – Anaesthesia

Editoriais:

In search of the perfect outcome in neuroanaesthesia and neurocritical care

Anaesthesia and the older brain: what should we do?

Artigos de revisão:

Implications of nocebo in anaesthesia care

Chronic subdural haematoma: the role of peri-operative medicine in a common form of reversible brain injury

Acute peri-operative neurocognitive disorders: a narrative review

Pragmatic sedation strategies to prevent secondary brain injury in low-resource settings

Delirium and COVID-19: a narrative review of emerging evidence

Anaesthesia for mechanical thrombectomy: a narrative review

Clinical applications of point-of-care ultrasound in brain injury: a narrative review

Management of status epilepticus: a narrative review

Evidence-based strategies to reduce the incidence of postoperative delirium: a narrative review

Management of traumatic brain injury: a narrative review of current evidence

Peri-operative neurological monitoring with electroencephalography and cerebral oximetry: a narrative review

Peri-operative management of patients with Parkinson’s disease

Estudo randomizado | Entre pacientes internados com COVID-19 sob risco de tromboembolismo venoso, a tromboprofilaxia pós-alta hospitalar com rivaroxabam por 35 dias pode melhorar os desfechos.

17 Dez, 2021 | 12:26h

Rivaroxaban versus no anticoagulation for post-discharge thromboprophylaxis after hospitalisation for COVID-19 (MICHELLE): an open-label, multicentre, randomised, controlled trial – The Lancet

Comentário convidado: Anticoagulation in COVID-19 – The Lancet

 

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Diretriz NICE | Insuficiência cardíaca aguda: diagnóstico e tratamento.

17 Dez, 2021 | 12:16h

Acute heart failure: diagnosis and management – National Institute for Health and Care Excellence

Conteúdo relacionado: #ESCCongress – 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure – SGLT2 inhibitors are now recommended for patients with heart failure with reduced ejection fraction regardless of the presence of diabetes.

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