Terapia Intensiva
Análise sistemática | Impacto global da resistência bacteriana a antibióticos em 2019.
20 Jan, 2022 | 23:06hGlobal burden of bacterial antimicrobial resistance in 2019: a systematic analysis – The Lancet
Comunicado de imprensa: An estimated 1.2 million people died in 2019 from antibiotic-resistant bacterial infections, more deaths than HIV/AIDS or malaria – The Lancet
Editorial: Antimicrobial resistance: time to repurpose the Global Fund – The Lancet
Comentário: Antimicrobial resistance now a leading cause of death worldwide, study finds – The Guardian
Comentário no Twitter
NEW—An estimated 1.2 million people died in 2019 from antibiotic-resistant bacterial infections, more deaths than HIV/AIDS or malaria.#GRAMPaper reveals the scale of antimicrobial resistance (#AMR), now a leading cause of death worldwide: https://t.co/2h5UEKemEq #AMRSOS pic.twitter.com/aWLhmdirJ8
— The Lancet (@TheLancet) January 20, 2022
Estudo randomizado | Em adultos com doença crítica, o uso de solução balanceada de multieletrólitos não reduziu o risco de morte ou lesão renal aguda em comparação à solução salina padrão.
20 Jan, 2022 | 22:05hBalanced Multielectrolyte Solution versus Saline in Critically Ill Adults – New England Journal of Medicine (link para o resumo – $ para o texto completo)
Conteúdos relacionados:
Comentário no Twitter
Trial of critically ill patients compared balanced multielectrolyte solution (BMES) with saline as fluid therapy in the ICU. There was no evidence that the risk of death or acute kidney injury was lower with the use of BMES than with saline. https://t.co/bmlg4BYaw8 pic.twitter.com/OlKGOM0Dmm
— NEJM (@NEJM) January 18, 2022
Diretrizes de prática clínica para o monitoramento do tratamento medicamentoso com teicoplanina.
20 Jan, 2022 | 21:53hEvidências atualizadas da Cochrane sobre COVID-19.
20 Jan, 2022 | 21:33hCOVID-19 evidence: a Cochrane round-up – Cochrane Library
Debate Pró-Con | Medida de troponina cardíaca como parte do seguimento rotineiro de dano miocárdico após cirurgia não cardíaca.
20 Jan, 2022 | 21:07hEstudo randomizado por cluster | Banho antisséptico com compressas impregnadas de clorexidina 2% e lavagem com luvas com octenidina 0,08% não foram efetivos na prevenção de infecções de corrente sanguínea associadas a cateter central em pacientes de terapia intensiva.
20 Jan, 2022 | 20:41hOMS recomenda dois novos medicamentos (baricitinibe e sotrovimabe) para tratar COVID-19.
20 Jan, 2022 | 20:20hComunicado de imprensa: WHO recommends two new drugs to treat COVID-19 – World Health Organization
Infográfico com recomendações atualizadas: A living WHO guideline on drugs for covid-19 – The BMJ
Comentários:
Comentário no Twitter (fio – clique para saber mais)
WHO has also conditionally recommended the use of sotrovimab for treating mild or moderate #COVID19 in patients who are at high risk of hospitalization: patients who are older, immunocompromised, with underlying conditions & those unvaccinated https://t.co/UAc21Wgxbl https://t.co/Z39mSKrOv5
— World Health Organization (WHO) (@WHO) January 14, 2022
Diretrizes para a provisão de terapia de suporte nutricional no adulto com doença crítica.
20 Jan, 2022 | 20:01hEstudo randomizado | Em pacientes submetidos a entubação endotraqueal, a sobrevida de 7 dias foi significativamente menor com etomidato vs. cetamina (77,3% vs. 85,1%), mas as taxas de sobrevida em 28 dias não foram significativamente diferentes (etomidato 64,1% vs. cetamina 66,8%, p = 0,294).
20 Jan, 2022 | 19:44h
Comentário no Twitter
Etomidate vs ketamine for emergency endotracheal intubation, RCT
💉801 critically ill pts assigned to receive etomidate (0.2–0.3 mg/kg) or ketamine (1–2 mg/kg)
💉day 7 survival significantly lower with etomidate
💉no significantly different day 28 survivalhttps://t.co/CkxufORC8A pic.twitter.com/xQ4AtCifc7— Intensive Care Medicine (@yourICM) December 17, 2021
Editorial | Quantidade de médicos na UTI, em busca das evidências: a promessa e as armadilhas da relação paciente–intensivista.
20 Jan, 2022 | 16:10hTowards evidence-based staffing: the promise and pitfalls of patient-to-intensivist ratios – Intensive Care Medicine (gratuito por tempo limitado)
Estudo relacionado: Association of patient-to-intensivist ratio with hospital mortality in Australia and New Zealand – Intensive Care Medicine
Comentário no Twitter
Evidence-based staffing, beyond pt-to-intensivist ratio: understanding tipping point of when workload is too much & quality of critical care diminishes essential for #ICU organization, beyond #COVID19 crisis.
📖Editorial https://t.co/63IrhL3MD6
📖Refers to https://t.co/eZAzwu4EbI pic.twitter.com/QpAtj4fcqc— Intensive Care Medicine (@yourICM) January 13, 2022