Acesso livre
Acesso livre

Terapia Intensiva

Estudo randomizado | Estudo preliminar sugere que a neostigmina pode melhorar a hipertensão intra-abdominal e a defecação em pacientes com pancreatite aguda.

8 Mar, 2022 | 16:43h

Randomized controlled trial: neostigmine for intra-abdominal hypertension in acute pancreatitis – Critical Care

Revisão sistemática | Distribuição dos subtipos de delirium motor na UTI.

8 Mar, 2022 | 16:42h

Distribution of delirium motor subtypes in the intensive care unit: a systematic scoping review – Critical Care

[Preprint] Estudo RECOVERY mostra que baricitinibe reduz mortes em pacientes internados com COVID-19.

8 Mar, 2022 | 16:22h

Comunicado de imprensa: RECOVERY trial shows Baricitinib reduces deaths in patients hospitalised with COVID-19 – University of Oxford

Estudo original: Baricitinib in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial and updated meta-analysis – medRxiv

Comentários:

Arthritis drug reduces mortality in severe COVID-19, huge clinical trial finds – Science

Covid-19: Anti-inflammatory treatment baricitinib reduces deaths in patients admitted to hospital, finds trial – The BMJ

Another life-saving Covid drug identified – BBC

Conteúdos relacionados:

WHO recommends two new drugs (Baricitinib and Sotrovimab) to treat COVID-19.

RCT: Baricitinib reduced mortality in hospitalized adults with COVID-19.

Randomized trial: Baricitinib plus remdesivir reduce recovery time in patients with COVID-19

 

Comentário do autor no Twitter (fio – clique para saber mais)

 

Revisão | Estratégias terapêuticas para Pseudomonas aeruginosa multirresistente.

8 Mar, 2022 | 15:03h

Therapeutic Strategies for Emerging Multidrug-Resistant Pseudomonas aeruginosa – Infectious Diseases and Therapy

Conteúdos relacionados:

IDSA guidance and ESCMID guidelines: complementary approaches toward a care standard for MDR Gram-negative infections – Clinical Microbiology and Infection

European guidelines for the treatment of infections caused by Multidrug-resistant Gram-negative bacilli.

IDSA Guidance on the Treatment of Antimicrobial-Resistant Gram-Negative Infections.

Acinetobacter baumannii resistente a carbapeném: colonização, infecção e opções atuais de tratamento.

8 Mar, 2022 | 15:02h

Carbapenem-resistant Acinetobacter baumannii: Colonization, Infection and Current Treatment Options – Infectious Diseases and Therapy

Conteúdos relacionados:

IDSA guidance and ESCMID guidelines: complementary approaches toward a care standard for MDR Gram-negative infections – Clinical Microbiology and Infection

European guidelines for the treatment of infections caused by Multidrug-resistant Gram-negative bacilli.

IDSA Guidance on the Treatment of Antimicrobial-Resistant Gram-Negative Infections.

Estudo de coorte | Troponina I de alta sensibilidade após cirurgia cardíaca e mortalidade em 30 dias.

3 Mar, 2022 | 16:51h

High-Sensitivity Troponin I after Cardiac Surgery and 30-Day Mortality – New England Journal of Medicine (link para o resumo – $ para o texto completo)

Comentários:

Better assessment of risk from heart surgery results in better patient outcomes – McMaster University

NEJM study evaluates levels of HS Troponin after cardiac surgery and risk of death – MedicalResearch

Conteúdo relacionado: Retrospective cohort: Serial high-sensitivity cardiac troponin I after coronary artery bypass grafting may add prognostic information for post-operative decision-making.

 

Comentário no Twitter

 

Estudo randomizado | Aspirina e heparina não fracionada aumentam o risco de hemorragia intracraniana sintomática em pacientes submetidos a tratamento endovascular de AVC isquêmico.

3 Mar, 2022 | 16:50h

Safety and efficacy of aspirin, unfractionated heparin, both, or neither during endovascular stroke treatment (MR CLEAN-MED): an open-label, multicentre, randomised controlled trial – The Lancet (link para o resumo – $ para o texto completo)

M-A | Uso de tocilizumabe e sarilumabe isoladamente ou em combinação com corticosteroides para Covid-19.

3 Mar, 2022 | 16:44h

Use of tocilizumab and sarilumab alone or in combination with corticosteroids for covid-19: systematic review and network meta-analysis – BMJ Medicine

Editorial: Treatment of severe covid-19 with interleukin 6 receptor inhibition – BMJ Medicine

Estudo relacionado (publicado recentemente): Mortality Rates Among Hospitalized Patients With COVID-19 Infection Treated With Tocilizumab and Corticosteroids: A Bayesian Reanalysis of a Previous Meta-analysis – JAMA Network Open

Estudo randomizado | Efeito da otimização de doses com base no monitoramento medicamentoso de piperacilina/tazobactam na disfunção de órgão relacionada a sepse em pacientes sépticos.

3 Mar, 2022 | 16:31h

Effect of therapeutic drug monitoring-based dose optimization of piperacillin/tazobactam on sepsis-related organ dysfunction in patients with sepsis: a randomized controlled trial – Intensive Care Medicine

 

Comentário no Twitter

 

Estudo observacional sugere que a norepinefrina é uma opção melhor do que a epinefrina em pacientes com parada cardíaca e choque pós-ressuscitação.

3 Mar, 2022 | 16:29h

Epinephrine versus norepinephrine in cardiac arrest patients with post-resuscitation shock – Intensive Care Medicine (link para o resumo – $ para o texto completo)

Conteúdo relacionado: Randomized Trial: Epinephrine vs Norepinephrine for Cardiogenic Shock After Acute Myocardial Infarction

 

 

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