Revisões Sistemáticas

Are inhaled #corticosteroids an effective treatment for people with mild #COVID19?
New #systematicreview from @CochraneAirways looks at using this well established treatment for asthma & COPD as a #COVIDtreatment https://t.co/dxUtudHLiW 1/4 pic.twitter.com/4nUs56Xfsg

— The Cochrane Library (@CochraneLibrary) March 9, 2022

Revisão sistemática | Otimização dos sistemas hospitalares de prescrição eletrônica.

11 Mar, 2022 | 15:07h

Optimizing Hospital Electronic Prescribing Systems: A Systematic Scoping Review – Journal of Patient Safety

Eficácia e segurança do tratamento não cirúrgico da apendicite aguda não complicada em comparação à apendicectomia: uma revisão abrangente de revisões sistemáticas e metanálises.

11 Mar, 2022 | 14:58h

Efficacy and Safety of Non-Operative Management of Uncomplicated Acute Appendicitis Compared to Appendectomy: An Umbrella Review of Systematic Reviews and Meta-Analyses – World Journal of Surgery

Conteúdos relacionados:

Cohort Study: Patient factors associated with appendectomy within 30 days of initiating antibiotic treatment for appendicitis – the presence of an appendicolith was associated with a nearly 2-fold increased risk of undergoing appendectomy within 30 days.

Review: Diagnosis of uncomplicated and complicated appendicitis in adults.

Another RCT evaluating the efficacy and quality of life of antibiotic-only treatment of acute uncomplicated appendicitis.

A Randomized trial comparing antibiotics with appendectomy for appendicitis

Antibiotics alone for uncomplicated appendicitis: Oral Moxifloxacin almost as good as intravenous Ertapenem + oral Levofloxacin

Observational study: 67.1% success rate with nonoperative management of children with uncomplicated appendicitis

Randomized Trial: Quality of Life and Patient Satisfaction at 7-Year Follow-up of Antibiotic Therapy vs. Appendectomy for Uncomplicated Acute Appendicitis

Meta-Analysis: Antibiotic Treatment vs. Appendectomy for Uncomplicated Acute Appendicitis in Adults and Children

Nonoperative treatment for nonperforated appendicitis in children: a systematic review and meta-analysis – Pediatric Surgery International

Revisão sistemática | Agentes antiplaquetários para doença renal crônica.

11 Mar, 2022 | 14:47h

Antiplatelet agents for chronic kidney disease – Cochrane Library

Comentário de estudo | Telemedicina em saúde mental é promissora como alternativa efetiva para a terapia individual presencial.

11 Mar, 2022 | 14:36h

Telemental health is promising as an effective and engaging alternative for in-person therapy #TeleMentalHealth – The Mental Elf

Estudo original: Implementation of Telemental Health Services Before COVID-19: Rapid Umbrella Review of Systematic Reviews – Journal of Medical Internet Research

Estudo randomizado | Em pacientes com câncer de tireoide de baixo risco, a tireoidectomia sem ablação por radioiodo foi não inferior à tireoidectomia com ablação por radioiodo em 3 anos.

10 Mar, 2022 | 15:57h

Thyroidectomy without Radioiodine in Patients with Low-Risk Thyroid Cancer – New England Journal of Medicine (link para o resumo – $ para o texto completo)

Comentário: New research casts doubt on a cornerstone of thyroid cancer treatment – STAT

Comentário no Twitter

In RCT involving patients with low-risk differentiated thyroid cancer undergoing thyroidectomy, a follow-up strategy that did not involve the use of radioiodine was noninferior to the use of radioiodine in the response to treatment at 3 years. https://t.co/RaJL3tdE4T pic.twitter.com/8nIPw50nkg

— NEJM (@NEJM) March 9, 2022

M-A | Eficácia comparativa e tolerabilidade de 32 antipsicóticos orais e injetáveis de longa duração para o tratamento de manutenção de adultos com esquizofrenia.

10 Mar, 2022 | 15:53h

Comparative efficacy and tolerability of 32 oral and long-acting injectable antipsychotics for the maintenance treatment of adults with schizophrenia: a systematic review and network meta-analysis – The Lancet (link para o resumo – $ para o texto completo)

Metanálise de estudos randomizados | Benefícios e prejuízos de anticoagulantes orais diretos e da heparina de baixo peso molecular para a tromboprofilaxia de pacientes submetidos a cirurgia não cardíaca.

10 Mar, 2022 | 15:52h

Benefits and harms of direct oral anticoagulation and low molecular weight heparin for thromboprophylaxis in patients undergoing non-cardiac surgery: systematic review and network meta-analysis of randomised trials – The BMJ

Comentário no Twitter

Led by Maura Marcucci, network meta-analysis of of 68 surgery #RCT's (45,445 patients; mainly #ortho) found that #DOAC's & #LMWH reduce #VTE but probably increase major bleeding to a similar extent. DOACs probably prevent symptomatic VTE more than #LMWH. https://t.co/7vrgVpfD3s pic.twitter.com/H5Fuq7p1hi

— Kari Tikkinen (@KariTikkinen) March 9, 2022

Revisão sistemática | Farmacoterapia para transtorno do estresse pós-traumático.

10 Mar, 2022 | 15:35h

Pharmacotherapy for post traumatic stress disorder (PTSD) – Cochrane Library

Metanálise de estudos randomizados comparando estratégias de transfusão de hemácias intraoperatória.

Revisão sistemática | Corticosteroides inalatórios para tratamento da COVID-19.