Pneumologia

Estudo randomizado | Mepolizumabe para crianças urbanas com asma eosinofílica propensas a exacerbação.

23 Ago, 2022 | 17:03h

Mepolizumab for urban children with exacerbation-prone eosinophilic asthma in the USA (MUPPITS-2): a randomised, double-blind, placebo-controlled, parallel-group trial – The Lancet (link para o resumo – $ para o texto completo)

Comentário: Mepolizumab Cuts Exacerbations in Children With Severe Asthma – HealthDay

 

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Estudo de coorte retrospectiva | Sintomas e fatores de risco para COVID longa em adultos não hospitalizados.

23 Ago, 2022 | 16:25h

Symptoms and risk factors for long COVID in non-hospitalized adults – Nature Medicine

Comentário: UK study finds over 100 symptoms of long COVID in non-hospitalized adults – News Medical

 

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M-A | Acurácia da oximetria de pulso na medida da saturação de oxigênio conforme os níveis de pigmentação cutânea.

23 Ago, 2022 | 16:18h

The accuracy of pulse oximetry in measuring oxygen saturation by levels of skin pigmentation: a systematic review and meta-analysis – BMC Medicine

Conteúdos relacionados:

Impact of ethnicity on the accuracy of measurements of oxygen saturations: A retrospective observational cohort study – eClinicalMedicine

Racial and Ethnic Discrepancy in Pulse Oximetry and Delayed Identification of Treatment Eligibility Among Patients With COVID-19 – JAMA Internal Medicine

Racial Bias in Pulse Oximetry Measurement – New England Journal of Medicine

Pulse Oximetry for Monitoring Patients with Covid-19 at Home — A Pragmatic, Randomized Trial – New England Journal of Medicine

Effectiveness and safety of pulse oximetry in remote patient monitoring of patients with COVID-19: a systematic review – The Lancet Digital Health

FDA issues alert on ‘limitations’ of pulse oximeters, without explicit mention of racial bias – STAT

Pulse Oximeter Accuracy and Limitations: FDA Safety Communication – U.S. Food & Drug Administration

 

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Estudo randomizado | Metformina, ivermectina e fluvoxamina não são benéficas para pacientes ambulatoriais obesos com Covid-19.

22 Ago, 2022 | 16:44h

Randomized Trial of Metformin, Ivermectin, and Fluvoxamine for Covid-19 – New England Journal of Medicine

Editorial: Time to Stop Using Ineffective Covid-19 Drugs – New England Journal of Medicine

 

Comentário no Twitter

In this trial involving overweight or obese outpatients with Covid-19, investigators found that none of three repurposed drugs (metformin, ivermectin, and fluvoxamine) reduced the risk of serious disease. https://t.co/8sd6R7CDK6 pic.twitter.com/bPZ6zeuZSA

— NEJM (@NEJM) August 17, 2022

 

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Análise agrupada de doença pulmonar intersticial relacionada a medicamentos e/ou pneumonite em 9 estudos de monoterapia com trastuzumabe deruxtecano.

22 Ago, 2022 | 16:34h

Pooled analysis of drug-related interstitial lung disease and/or pneumonitis in nine trastuzumab deruxtecan monotherapy studies – ESMO Open

Comentários:

Prompt recognition and treatment found effective for lung disease in patients who received new drug for advanced cancer – The Mount Sinai Health System

Trastuzumab deruxtecan-related ILD/pneumonitis characterized – medwire News

Conteúdo relacionado: Trastuzumab Deruxtecan-Induced Interstitial Lung Disease/Pneumonitis in ERBB2-Positive Advanced Solid Malignancies: A Systematic Review – Drugs

 

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Estudo randomizado | Efetividade de um programa de treinamento de exercícios domiciliar de longo prazo em pacientes com DPOC após reabilitação pulmonar.

22 Ago, 2022 | 16:31h

Effectiveness of a long-term home-based exercise training program in patients with COPD following pulmonary rehabilitation: A multi-center randomized controlled trial – CHEST

 

Comentário no Twitter

Effectiveness of a long-term home-based exercise training program in patients with COPD following pulmonary rehabilitation: A multi-center randomized controlled trialhttps://t.co/8u1nizaDNq pic.twitter.com/QwqzN1dDHK

— Physio Meets Science (@PhysioMeScience) August 17, 2022

Sob licença de Creative Commons

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Revisão | Síndrome da angústia respiratória aguda.

22 Ago, 2022 | 16:09h

Acute Respiratory Distress Syndrome – Emergency Medicine Clinics of North America

 

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Diretriz | Uso de plasma convalescente de COVID-19.

22 Ago, 2022 | 16:08h

Clinical Practice Guidelines From the Association for the Advancement of Blood and Biotherapies (AABB): COVID-19 Convalescent Plasma – Annals of Internal Medicine

Editorial: The Fast and the Furious: Chasing a Clinical Niche for COVID-19 Convalescent Plasma – Annals of Internal Medicine

Comunicado de imprensa: The AABB releases clinical practice guidelines for the appropriate use of COVID-19 convalescent plasma – American College of Physicians

 

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Estratificação de risco em pacientes com embolia pulmonar aguda: evidência atual e perspectivas.

22 Ago, 2022 | 15:16h

Risk Stratification in Patients with Acute Pulmonary Embolism: Current Evidence and Perspectives – Journal of Clinical Medicine

 

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Ventilação mecânica prolongada: desfechos e tratamento.

22 Ago, 2022 | 15:14h

Prolonged Mechanical Ventilation: Outcomes and Management – Journal of Clinical Medicine

 

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