Medicina Baseada em Evidências
Análise | Recomendações discordantes e inadequadas em diretrizes de consenso vs. diretrizes baseadas em evidências.
6 Dez, 2021 | 16:05hEditorial: A moratorium on strong recommendations is needed – The BMJ
Comentário: Can we trust strong recommendations based on low quality evidence? – The BMJ
Comentário no Twitter
NEW research finds that consensus based guidelines produce more recommendations violating the evidence based medicine principles than evidence based guidelines https://t.co/8eCGZfiNZ3
— The BMJ (@bmj_latest) November 28, 2021
Ensaios clínicos randomizados na terapia intensiva: passado, presente e futuro.
3 Dez, 2021 | 11:00hRandomised clinical trials in critical care: past, present and future – Intensive Care Medicine
Comentário no Twitter
RCTs in critical care, history, major challenges & limitations, recent developments trying to solve some of these
📊conventional & novel RCTs
📊rationale for choosing methodological approach (advantages/potential disadvantages – pros/cons)@CritCareReviewshttps://t.co/kjCw7dFuou pic.twitter.com/xS9lHK4cuY— Intens Care Med (@yourICM) December 2, 2021
Recomendações práticas sobre a quantificação e a interpretação dos efeitos de tratamentos diante de riscos concorrentes terminais.
3 Dez, 2021 | 10:59hPractical Recommendations on Quantifying and Interpreting Treatment Effects in the Presence of Terminal Competing Risks: A Review – JAMA Cardiology (gratuito por tempo limitado)
Comentário no Twitter
Our paper on how to analyze and interpret terminal competing risks in cardiovascular clinical trials just out in JAMA Cardiology. Always a pleasure to collaborate with LJ Wei, Marc Pfeffer and Scott Solomon and their great teams. https://t.co/9hk6wru7yU pic.twitter.com/64sgoOjldQ
— Otavio Berwanger (@OtavioBerwanger) December 1, 2021
Perspectiva | Danos vs. benefícios na medicina: não é somente uma decisão para especialistas.
3 Dez, 2021 | 10:56hHarms versus benefits in medicine: not just a decision for experts – The Conversation
Diretrizes desenvolvidas sob pressão. O caso das diretrizes “rápidas” e de baixa qualidade para COVID-19 e soluções potenciais.
1 Dez, 2021 | 15:33hVariante Ômicron: vídeos com opiniões sobre o tema.
29 Nov, 2021 | 11:02h- Omicron: What we know so far about the new COVID-19 variant | DW News
- OMG Omicron? | A Doctor Explains, LIVE – ZDoggMD
Revisão | Guia simplificado para interpretar valores de p, intervalos de confiança e magnitude de efeitos.
29 Nov, 2021 | 10:46hThe clinician’s guide to p values, confidence intervals, and magnitude of effects – Eye (se este link tiver acesso pago, tente este)
Conteúdos relacionados:
Bayesian interpretation of p values in clinical trials.
Scientists Rise Up Against Statistical Significance
.050 shades of grey in p-value cutoffs
What a nerdy debate about p-values shows about science — and how to fix it – VOX
Big names in statistics want to shake up much-maligned P value – Nature News
‘One-size-fits-all’ threshold for P values under fire – Nature News
Statisticians issue warning over misuse of P values – Nature News
Understanding common misconceptions about p-values – The 20% Statistician
Revisão | Estudos para avaliação de testes diagnósticos.
29 Nov, 2021 | 10:41hStudies for the Evaluation of Diagnostic Tests – Deutsches Ärzteblatt International
Opinião | O uso errado e o abuso de metanálises.
26 Nov, 2021 | 11:45hThe misuse and abuse of meta-analyses – Science-Based Medicine