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Infectologia

Revisão e M-A | Reabilitação pulmonar pós-Covid.

8 Abr, 2022 | 17:18h

Estudo 1: The effectiveness of pulmonary rehabilitation for Post-COVID symptoms: A rapid review of the literature – Respiratory Medicine

Estudo 2: Effect of Pulmonary Rehabilitation for Patients With Post-COVID-19: A Systematic Review and Meta-Analysis – Frontiers in Medicine

Diretriz de consenso | Definição, diagnóstico e tratamento da mucormicose pulmonar associada a COVID-19.

6 Abr, 2022 | 12:57h

Definition, diagnosis, and management of COVID-19-associated pulmonary mucormycosis: Delphi consensus statement from the Fungal Infection Study Forum and Academy of Pulmonary Sciences, India – The Lancet Infectious Diseases

Perspectiva | As evidências sobre a 4ª dose das vacinas contra Covid & a questão complicada dos limites de idade.

6 Abr, 2022 | 12:53h

The Evidence On 4th Doses of Covid Vaccines & the Thorny Question of Age Thresholds – Absolutely Maybe Blog, by Hilda Bastian

Conteúdos relacionados:

U.S. approves second Covid-19 booster for people 50 and older and immunocompromised individuals.

[Preprint] Retrospective cohort study: second booster vaccine and Covid-19 mortality in adults 60 to 100 years old.

Among health care workers, a fourth dose vaccine effectiveness against any SARS-CoV-2 Omicron variant infection was 30% for the Pfizer–BioNTech and 11% for the Moderna.

[Preprint] Fourth dose of COVID vaccine offers only slight boost against Omicron infection.

Covid-19: Fourth vaccine doses—who needs them and why?

[Not published yet] Study in Israel finds fourth COVID booster has limited efficacy.

 

Comentário no Twitter

 

Estudo randomizado | Eficácia, segurança e imunogenicidade da vacina de DNA contra SARS-CoV-2 (ZyCoV-D).

6 Abr, 2022 | 12:48h

Efficacy, safety, and immunogenicity of the DNA SARS-CoV-2 vaccine (ZyCoV-D): the interim efficacy results of a phase 3, randomised, double-blind, placebo-controlled study in India – The Lancet

Comentário convidado: DNA vaccines join the fight against COVID-19 – The Lancet

 

Comentário no Twitter

 

Estudo de coorte | Mudança nas taxas de mortalidade por doença cardíaca e AVC antes e durante a pandemia de Covid-19.

6 Abr, 2022 | 12:46h

Age-Adjusted Mortality Rates and Age and Risk–Associated Contributions to Change in Heart Disease and Stroke Mortality, 2011-2019 and 2019-2020 – JAMA Network Open

Comentários:

Several-Fold Increase in Stroke and Heart Disease Deaths During COVID-19 Pandemic – NeurologyToday

2019 to 2020 Saw Risk-Linked Deaths From Heart Disease, Stroke Up – HealthDay

 

Comentário do autor no Twitter (fio – clique pra saber mais). Artigo e imagens sob CC-BY License

 

Revisão sistemática | Tempo de administração antibiótica, debridamento de feridas e estágios da cirurgia reconstrutiva para fraturas expostas de ossos longos de membros superiores e inferiores.

6 Abr, 2022 | 12:21h

Timing of antibiotic administration, wound debridement, and the stages of reconstructive surgery for open long bone fractures of the upper and lower limbs – Cochrane Library

Resumo: The timing of treatment for broken bones in the legs and arms that also have open wounds – Cochrane Library

Revisão | Combatendo a resistência antifúngica, uma ameaça emergente para a saúde humana.

6 Abr, 2022 | 12:11h

Tackling the emerging threat of antifungal resistance to human health – Nature Reviews Microbiology (se o acesso a este link for pago, tente este)

Estratégia da OMS para preparo, prontidão e plano de resposta para o fim da emergência global de Covid-19 em 2022.

5 Abr, 2022 | 12:30h

Strategic Preparedness, Readiness and Response Plan to End the Global COVID-19 Emergency in 2022 – World Health Organization

 

Comentário no Twitter (fio – clique para saber mais)

 

Segurança, tolerabilidade e cinética viral durante o desafio do SARS-CoV-2 humano em adultos jovens (infectando indivíduos deliberadamente em ambiente controlado).

5 Abr, 2022 | 12:20h

Safety, tolerability and viral kinetics during SARS-CoV-2 human challenge in young adults – Nature Medicine

Comentários:

Understanding COVID-19 through human challenge models – Nature Medicine

First human challenge study of Covid-19 yields valuable insights about how we get sick – CNN

First Human Challenge Trial Shows How COVID-19 Strikes – HealthDay

Conteúdos relacionados:

Scientists deliberately gave people COVID — here’s what they learnt.

[Preprint] Results from the first Covid-19 human challenge study (deliberately infecting individuals in a controlled environment).

Perspective | SARS-CoV-2 human challenge studies — establishing the model during an evolving pandemic.

World’s first coronavirus “Human Challenge” study receives ethics approval in the UK  (vários textos sobre o assunto)

Are SARS-CoV-2 Human Challenge Trials Ethical? – “A clinical trial is underway in the UK in which young, healthy participants are exposed deliberately to SARS-CoV-2 to assess the viral inoculum needed to produce an infection and to test vaccine efficacy”.

 

Comentário no Twitter

 

Estudo randomizado | Dose maior de primaquina é mais efetiva na prevenção de recorrência de malária por Plasmodium vivax em comparação com a dose padrão.

5 Abr, 2022 | 12:18h

Higher-Dose Primaquine to Prevent Relapse of Plasmodium vivax Malaria – New England Journal of Medicine

 

Comentários no Twitter

 

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