Estudo randomizado | Dose maior de primaquina é mais efetiva na prevenção de recorrência de malária por Plasmodium vivax em comparação com a dose padrão.

Higher-Dose Primaquine to Prevent Relapse of Plasmodium vivax Malaria – New England Journal of Medicine

Comentários no Twitter

To prevent relapse of Plasmodium vivax malaria, primaquine at a total dose of 7.0 mg per kilogram had higher efficacy than a total dose of 3.5 mg per kilogram. https://t.co/qIu27ruhKP pic.twitter.com/HdTNhqB0J1

— NEJM (@NEJM) April 1, 2022

In most of the Americas, recommended primaquine-based therapy for P. vivax malaria has moderate efficacy for preventing relapse. Whether higher-dose primaquine might reduce recurrence is unknown. New research findings are summarized in a short video. https://t.co/aFt9gNGg0m pic.twitter.com/oiAkLMgPIJ

— NEJM (@NEJM) April 2, 2022