Acesso livre
Acesso livre

Infectologia

Estudo preliminar mostrou que uma supressão viral prolongada é factível com terapia de anticorpos anti-HIV.

19 Abr, 2022 | 12:26h

Prolonged viral suppression with anti-HIV-1 antibody therapy – Nature

 

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Validação prospectiva de um teste rápido de expressão gênica do hospedeiro para diferenciar infecção respiratória bacteriana de viral.

19 Abr, 2022 | 12:20h

Prospective Validation of a Rapid Host Gene Expression Test to Discriminate Bacterial From Viral Respiratory Infection – JAMA Network Open

 

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Risco de transmissão domiciliar assintomática de infecção por Clostridioides difficile associada com internação recente de membros da família.

19 Abr, 2022 | 12:13h

Risk for Asymptomatic Household Transmission of Clostridioides difficile Infection Associated with Recently Hospitalized Family Members – Emerging Infectious Diseases

Comentário: Recently Discharged Patients Pose Risk for Spreading C. Difficile Infection – HealthDay

Revisão sistemática | Efeito das transferências condicionais de renda no controle de doenças tropicais negligenciadas.

19 Abr, 2022 | 12:12h

The effect of conditional cash transfers on the control of neglected tropical disease: a systematic review – The Lancet Global Health

Comentário convidado: The potential of conditional cash transfers for the control of neglected tropical diseases – The Lancet Global Health

Conteúdo relacionado: Does giving money to people, in low- and middle-income countries, without conditions attached lead to better health and other life improvements? – Cochrane Library

 

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Análise observacional em Israel mostrou que a 4ª dose da vacina da Pfizer pode reduzir o risco de curto prazo dos desfechos adversos relacionados a Covid-19.

18 Abr, 2022 | 15:31h

Fourth Dose of BNT162b2 mRNA Covid-19 Vaccine in a Nationwide Setting – New England Journal of Medicine

Editorial: Covid-19 Boosters — Where from Here?

Conteúdos relacionados:

COVID-19: Joint statement from ECDC and EMA on the administration of a fourth dose of mRNA vaccines.

Observational study suggests a fourth dose of the Pfizer vaccine provided additional protection against severe disease in patients 60 years of age or older during the Omicron wave in Israel.

Perspective: The evidence on 4th doses of covid vaccines & the thorny question of age thresholds.

U.S. approves second Covid-19 booster for people 50 and older and immunocompromised individuals.

[Preprint] Retrospective cohort study: second booster vaccine and Covid-19 mortality in adults 60 to 100 years old.

Among health care workers, a fourth dose vaccine effectiveness against any SARS-CoV-2 Omicron variant infection was 30% for the Pfizer–BioNTech and 11% for the Moderna.

[Preprint] Fourth dose of COVID vaccine offers only slight boost against Omicron infection.

Covid-19: Fourth vaccine doses—who needs them and why?

[Not published yet] Study in Israel finds fourth COVID booster has limited efficacy.

 

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Covid-19: qual é a evidência para o uso do antiviral molnupiravir?

18 Abr, 2022 | 15:30h

Covid-19: What is the evidence for the antiviral molnupiravir? – The BMJ

Estudo mostrou baixas taxas de COVID-19 grave em crianças internadas com infecção por SARS-CoV-2 confirmada.

18 Abr, 2022 | 15:29h

Very low rates of severe COVID-19 in children hospitalised with confirmed SARS-CoV-2 infection in London, England – Journal of Infection

Comentário: Severe COVID-19 extremely rare among children – News Medical

Conteúdos relacionados:

[Preprint] Risk of Hospitalization, severe disease, and mortality due to COVID-19 in children with SARS-CoV-2 infection in Germany – “overall hospitalization rate associated with SARS-CoV-2 infection was 35.9 per 10,000 children, ICU admission rate was 1.7 per 10,000 and case fatality was 0.09 per 10,000”.

Deaths in children and young people in England after SARS-CoV-2 infection during the first pandemic year – “In total, 99.995% of children and young people with a positive SARS-CoV-2 test survived”.

Editorial: COVID-19 vaccines for children – “Although it is true that most children experience asymptomatic or mild disease, some will get quite sick, and a small number will die. It’s why children are vaccinated against influenza, meningitis, chickenpox, and hepatitis”.

COVID-19 disease severity in children infected with the Omicron variant.

Risk factors for PICU admission and death among children and young people hospitalized with COVID-19 and PIMS-TS in England during the first pandemic year.

Study identifies risk factors for severe CoviD-19 in children.

A nationwide cohort study in Denmark showed Long Covid in children is rare and mainly of short duration.

International study identifies predictors of severe outcomes in children with COVID-19.

Estudo randomizado | Eficácia, segurança e imunogenicidade de uma vacina de enterovírus 71 inativado em bebês e crianças.

18 Abr, 2022 | 15:26h

Efficacy, safety, and immunogenicity of an inactivated, adjuvanted enterovirus 71 vaccine in infants and children: a multiregion, double-blind, randomised, placebo-controlled, phase 3 trial – The Lancet (link para o resumo – $ para o texto completo)

Revisão | Papel do radiologista no diagnóstico e tratamento de duas formas de equinococose hepática.

18 Abr, 2022 | 14:58h

Role of the radiologist in the diagnosis and management of the two forms of hepatic echinococcosis – Insights into Imaging

Estudo randomizado por cluster | Antibioticoprofilaxia mais curta (menos de 24 horas após a cirurgia) é não inferior a um regime mais estendido (24-48 horas) após cirurgia ortopédica limpa.

14 Abr, 2022 | 17:47h

Effect of Antimicrobial Prophylaxis Duration on Health Care–Associated Infections After Clean Orthopedic Surgery: A Cluster Randomized Trial – JAMA Network Open

 

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