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Imunologia Pediátrica

Dez coisas a saber sobre a síndrome inflamatória multissistêmica em crianças (multisystem inflammatory syndrome in children – MIS-C).

4 Nov, 2021 | 12:01h

Ten Things to Know About MIS-C – American College of Cardiology

Conteúdos relacionados:

Cohort study: long term follow-up showed most patients with post–COVID-19 Multisystem Inflammatory Syndrome in Children had good outcomes with no significant medium- or long-term sequelae.

Kawasaki Disease and Multisystem Inflammatory Syndrome in Children: An Overview and Comparison.

Cohort study: Six month follow-up of Multisystem Inflammatory Syndrome in Children.

Cohort study: Among children with Multisystem Inflammatory Syndrome (MIS-C) associated with Covid-19, there was no evidence that recovery differed after primary treatment with intravenous immune globulin (IVIG) alone, IVIG plus glucocorticoids, or glucocorticoids alone.

Cohort study: Among children with Multisystem Inflammatory Syndrome (MIS-C) associated with Covid-19, initial treatment with intravenous immune globulin (IVIG) plus glucocorticoids was associated with a lower risk of new or persistent cardiovascular dysfunction than IVIG alone.

Cohort study showed that the incidence of Multisystem Inflammatory Syndrome in Children (MIS-C) was 316 persons per 1 000 000 SARS-CoV-2 infections in persons younger than 21 years. The incidence was higher among Black, Hispanic or Latino, and Asian or Pacific Islander persons.

Cohort study showed good recovery for most children 6 months after Pediatric Inflammatory Multisystem Syndrome (PIMS-TS) associated with SARS-CoV-2.

Epidemiology of Multisystem Inflammatory Syndrome in Children: A Step Closer to Understanding Who, Where, and When

Neurologic involvement in children and adolescents with COVID-19 or Multisystem Inflammatory Syndrome

Clinical Update: Acute covid-19 and multisystem inflammatory syndrome in children

Differences in characteristics and outcomes of children and adolescents with Multisystem Inflammatory Syndrome in Children (MIS-C) vs. severe acute COVID-19

Cutaneous findings in SARS-CoV-2-associated Multisystem Inflammatory Disease in Children (MIS-C)

SR: Multisystem inflammatory syndrome in children related to COVID-19

Observational study: The combination of Immunoglobulins + Methylprednisolone was associated with a better course of fever compared to Immunoglobulins alone in Multisystem Inflammatory Syndrome in children

ACR Guidance for pediatric patients with multisystem inflammatory syndrome in children associated with SARS‐CoV‐2

New systematic review of Multisystem Inflammatory Syndrome in Children Associated With SARS-CoV-2 infection summarizes the clinical features, management, and outcomes of the disease, showing favorable outcomes for the majority of children

Podcast | Dicas sobre dermatite atópica.

27 Out, 2021 | 12:18h

Atopic Dermatitis Pearls – The Cribsiders

Estudo de coorte | Seguimento de longo prazo mostrou que a maioria das crianças com síndrome inflamatória multissistêmica pós-COVID-19 teve bons desfechos, sem sequelas significativas no médio ou no longo prazo.

12 Set, 2021 | 22:14h

One-Year Outcomes of Critical Care Patients Post–COVID-19 Multisystem Inflammatory Syndrome in Children – JAMA Pediatrics

Comentário: Outcome Good at One Year for Majority of PIMS-TS Patients – HealthDay

 

Comentário no Twitter

 

Crianças e COVID: por que sistemas imunológicos jovens ainda estão no topo.

8 Set, 2021 | 15:20h

Kids and COVID: why young immune systems are still on top – Nature

Estudo de coorte | Seguimento de 6 meses da síndrome inflamatória multissistêmica em crianças.

3 Ago, 2021 | 11:32h

Six Month Follow-up of Patients With Multisystem Inflammatory Syndrome in Children – Pediatrics (PDF)

Especialistas recomendam doses de vacina contra a Covid para algumas pessoas menores de 18 anos no Reino Unido – “A sugestão é que a vacina da Pfizer seja oferecida a jovens entre 16 e 18 anos que façam parte de grupos prioritários ou que vivam com pessoas cujo sistema imunológico esteja debilitado.”

20 Jul, 2021 | 10:52h

Comentários: Experts recommend Covid jabs for some under-18s in UK – BBC

Ver relatório: JCVI statement on COVID-19 vaccination of children and young people aged 12 to 17 years: 15 July 2021 – Joint Committee on Vaccination and Immunisation

Muitas crianças da Nova Zelândia estão adoecendo em virtude da “falta de imunidade” gerada pelas medidas de restrição contra a pandemia de Covid.

14 Jul, 2021 | 11:42h

New Zealand children falling ill in high numbers due to Covid ‘immunity debt’ – The Guardian

Relacionado: New Zealand, where Covid-19 is dormant, fights another respiratory virus – The New York Times

CDC | Vacinas de mRNA parecem ter ligação com casos de miocardite e pericardite – 1.226 casos de miocardite ou pericardite foram relatados, a maioria em pessoas com menos de 30 anos de idade.

24 Jun, 2021 | 11:00h

CDC safety group says there’s a likely link between rare heart inflammation in young people after Covid shot – CNBC

Ver também: Experts: mRNA COVID-19 vaccines likely tied to heart inflammation – CIDRAP

Relacionados: Case series: 7 cases of myocarditis following mRNA-based COVID-19 vaccination. E Case series: clinical and cardiac magnetic resonance imaging findings of 4 cases of myocarditis following mRNA-based COVID-19 vaccination. E Case series: symptomatic acute myocarditis in 7 adolescents following mRNA COVID-19 vaccination. E CDC says heart inflammation cases were higher than expected in 16- to 24-year-olds after second Covid vaccine shot, but still rare. E Israel reports link between rare cases of heart inflammation and COVID-19 vaccination in young men. E CDC is investigating several reports that teenagers and young adults may have developed myocarditis after receiving mRNA vaccines. Most cases were mild, more often in males than females, more often following dose 2 than dose 1, and typically, within 4 days after vaccination.

Estudo de coorte | Em crianças com síndrome inflamatória multissistêmica (multisystem inflammatory syndrome – MIS-C) associada à Covid-19, não houve evidência de diferenças na recuperação após tratamento inicial com imunoglobulina intravenosa (IGIV) isolada, IGIV com glicocorticoides ou glicocorticoides isolados.

18 Jun, 2021 | 10:42h

Treatment of Multisystem Inflammatory Syndrome in Children – New England Journal of Medicine

Editorial: Immunotherapy for MIS-C — IVIG, Glucocorticoids, and Biologics

Comentários: Steroids may be effective treatment for COVID-19 complications in children – Imperial College London E Expert reaction to study looking at treatments for COVID-19 complications in children – Science Media Centre

Estudo de coorte | Em crianças com síndrome inflamatória multissistêmica (multisystem inflammatory syndrome – MIS-C) associada à Covid-19, o tratamento inicial com imunoglobulina intravenosa (IGIV) e glicocorticoides foi associado com menor risco de disfunção cardiovascular nova ou persistente em comparação ao tratamento com IGIV isolada.

18 Jun, 2021 | 10:40h

Multisystem Inflammatory Syndrome in Children — Initial Therapy and Outcomes – New England Journal of Medicine

Editorial: Immunotherapy for MIS-C — IVIG, Glucocorticoids, and Biologics

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