Acesso livre
Acesso livre

Hematologia Geral

Estudo randomizado | Mais um estudo mostra que plasma convalescente não melhora os desfechos em pacientes criticamente doentes com Covid-19.

5 Out, 2021 | 11:32h

Effect of Convalescent Plasma on Organ Support–Free Days in Critically Ill Patients With COVID-19 A Randomized Clinical Trial – JAMA

Commentary: Convalescent plasma futile as treatment for critically ill COVID-19 patients, study finds – University of Pittsburgh

Conteúdos relacionados:

RCT: Convalescent plasma does not improve outcomes and may be harmful to hospitalized patients with COVID-19.

NIH study shows no significant benefit of convalescent plasma for COVID-19 outpatients with early symptoms.

M-A: Convalescent plasma is safe but does not improve outcomes in the treatment of COVID-19.

RECOVERY Trial: No benefit from convalescent plasma in patients admitted to hospital with COVID-19.

Trombose e trombocitopenia imune induzidas por vacina: resumo da diretriz NICE.

4 Out, 2021 | 10:36h

Vaccine induced immune thrombocytopenia and thrombosis: summary of NICE guidance – The BMJ

Diretriz original: NICE COVID-19 rapid guideline: vaccine-induced immune thrombocytopenia and thrombosis.

Conteúdos relacionados:

Clinical features of vaccine-induced immune thrombocytopenia and thrombosis.

Review: Clinical characteristics and pharmacological management of COVID-19 vaccine–induced immune thrombotic thrombocytopenia with cerebral venous sinus thrombosis.

Vaccine-induced immune thrombotic thrombocytopenia: what we know and do not know.

Very rare cases of thrombosis with thrombocytopenia syndrome (TTS) after AstraZeneca vaccine: a global safety database analysis – the estimated rate of TTS after the first dose was 8.1 per million vaccinees; after the second dose, the estimated rate was 2.3 per million vaccinees. (vários artigos e fontes sobre o tema)

Revisão sistemática | Testes de rotina para investigar câncer em pacientes com coágulos sanguíneos não provocados nas pernas e nos pulmões podem melhorar os desfechos?

4 Out, 2021 | 10:16h

Resumo: Does testing for cancer in people with unprovoked blood clots in the legs and lungs reduce cancer- and blood clot-related death and illness? – Cochrane Library

Artigo original: Effect of testing for cancer on cancer‐ or venous thromboembolism (VTE)‐related mortality and morbidity in people with unprovoked VTE – Cochrane Library

Mais uma metanálise sugere que anticoagulação profilática é a melhor opção para pacientes hospitalizados com Covid-19.

1 Out, 2021 | 22:02h

A Systematic Review and a Meta-Analysis Comparing Prophylactic and Therapeutic Low Molecular Weight Heparins for Mortality Reduction in 32,688 COVID-19 Patients – Frontiers in Pharmacology

Conteúdo relacionado: M-A: Safety and efficacy of different prophylactic anticoagulation dosing regimens in critically and non-critically ill patients with COVID-19 – According to this analysis, standard-dose prophylactic anticoagulation should be the standard of care for hospitalized patients with COVID-19 who do not have an indication for therapeutic anticoagulation, irrespective of disease severity.

Diretriz de prática clínica da AGA sobre o tratamento de distúrbios de coagulação em pacientes com cirrose.

1 Out, 2021 | 19:20h

AGA Clinical Practice Guideline on the Management of Coagulation Disorders in Patients With Cirrhosis – Gastroenterology

Ver também: AGA Technical Review on Coagulation in Cirrhosis – Gastroenterology

Avaliação de custo-efetividade da transfusão de plasma em ambiente pré-hospitalar em pacientes de trauma instáveis: uma análise secundária do estudo PAMPer.

27 Set, 2021 | 13:16h

Evaluating the Cost-effectiveness of Prehospital Plasma Transfusion in Unstable Trauma Patients: A Secondary Analysis of the PAMPer Trial – JAMA Surgery (gratuito por tempo limitado)

Comentários:

CHEERS to You on a Well-done Cost-effectiveness Analysis of Prehospital Plasma for Helicopter Resuscitation of Patients With Traumatic Shock – JAMA Surgery (gratuito por tempo limitado)

Prehospital Plasma: A Cheap, Effective Way to Save Trauma Patients’ Lives? – BreakingMed

 

Comentário no Twitter

 

M-A | Segurança e eficácia de diferentes regimes de anticoagulação profilática em pacientes criticamente e não criticamente doentes com COVID-19 – De acordo com esta análise, a dose usual de anticoagulação profilática deve ser o padrão de cuidado para pacientes hospitalizados com COVID-19, independentemente da gravidade da doença.

27 Set, 2021 | 10:56h

Safety and efficacy of different prophylactic anticoagulation dosing regimens in critically and non-critically ill patients with COVID-19: A systematic review and meta-analysis of randomized controlled trials – European Heart Journal – Cardiovascular Pharmacotherapy

 

Comentário no Twitter (fio – clique para saber mais)

 

Revisão | Lesão pulmonar aguda relacionada à transfusão no perioperatório.

27 Set, 2021 | 10:39h

Transfusion-related Acute Lung Injury in the Perioperative Patient – Anesthesiology

Estudo randomizado | Rivaroxabam não tem impacto sobre a progressão da doença e a resolução dos sintomas em adultos de alto risco com COVID-19 leve.

17 Set, 2021 | 13:12h

Randomized study of rivaroxaban vs. placebo on disease progression and symptoms resolution in high-risk adults with mild COVID-19 – Clinical Infectious Diseases

Revisão | Teste para trombofilias na era dos anticoagulantes orais diretos.

17 Set, 2021 | 12:47h

Thrombophilia testing in the era of direct oral anticoagulants – Clinical Medicine Journal

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