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Acesso livre

Gestão de Antimicrobianos

M-A | Eficácia de diferentes antissépticos cutâneos pré-operatórios na incidência de infecções de sítio cirúrgico.

17 Out, 2022 | 13:51h

Efficacy of different preoperative skin antiseptics on the incidence of surgical site infections: a systematic review, GRADE assessment, and network meta-analysis – The Lancet Microbe

Conteúdos relacionados:

Antiseptic Skin Agents to Prevent Surgical Site Infection After Incisional Surgery: A Randomized, Three-armed Combined Non-inferiority and Superiority Clinical Trial (NEWSkin Prep Study) – Annals of Surgery (link para o resumo – $ para o texto completo)

Alcoholic chlorhexidine skin preparation or triclosan-coated sutures to reduce surgical site infection: a systematic review and meta-analysis of high-quality randomised controlled trials – The Lancet Infectious Diseases

Reducing surgical site infections in low-income and middle-income countries (FALCON): a pragmatic, multicentre, stratified, randomised controlled trial – The Lancet

 

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Ilustrações sob licença de Creative Commons Attribution (CC BY 4.0)

 

Recomendações de consenso | Como minimizar o risco de transmissão do vírus da varíola dos macacos durante o transplante de microbiota fecal.

17 Out, 2022 | 13:04h

Minimising the risk of monkeypox virus transmission during faecal microbiota transplantation: recommendations from a European expert panel – The Lancet Gastroenterology & Hepatology

 

Resumo de diretriz | Gestão de diagnóstico para infecções de trato urinário.

17 Out, 2022 | 12:53h

Diagnostic stewardship for urinary tract infection: A snapshot of the expert guidance – Cleveland Clinic Journal of Medicine

Diretriz original: Optimal Urine Culture Diagnostic Stewardship Practice—Results from an Expert Modified-Delphi Procedure – Clinical Infectious Diseases

 

Estudo randomizado | Antibióticos tópicos reduzem o tempo de cura clínica em crianças com conjuntivite infecciosa.

6 Out, 2022 | 12:56h

Effect of Topical Antibiotics on Duration of Acute Infective Conjunctivitis in Children: A Randomized Clinical Trial and a Systematic Review and Meta-analysis – JAMA Network Open

Comentários:

Topical Antibiotics Linked With Reduced Duration of Acute Infective Conjunctivitis in Children – AJMC

Topical Antibiotics Shorten Duration of Conjunctival Symptoms – HealthDay

 

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Estudo randomizado | Antibioticoprofilaxia vs. nenhuma profilaxia na cirurgia de câncer de mama.

4 Out, 2022 | 12:26h

Antibiotic prophylaxis in breast cancer surgery (PAUS trial): randomised clinical double-blind parallel-group multicentre superiority trial – British Journal of Surgery (link para o resumo – $ para o texto completo)

 

Perspectiva/revisão | Broncoscopia para diagnóstico de pneumonia associada a ventilador mecânico.

3 Out, 2022 | 12:54h

Bronchoscopy for diagnosis of ventilator-associated pneumonia – Intensive Care Medicine

 

Resumo de diretriz | Tratamento de pacientes com alergia a antibiótico suspeita ou confirmada.

12 Set, 2022 | 11:34h

Management of Patients with Suspected or Confirmed Antibiotic Allergy. Executive Summary of Guidance from the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC), the Spanish Society of Allergy and Clinical Immunology (SEAIC), the Spanish Society of Hospital Pharmacy (SEFH) and the Spanish Society of Intensive Medicine and Coronary Care Units (SEMICYUC) – Journal of Investigational Allergology and Clinical Immunology (PDF)

Conteúdos relacionados:

The prevalence of penicillin allergy labeling ranged from 0.9% to 10.2% across practices in a large pediatric cohort, raising questions regarding the validity of those labels and the unnecessary use of second-line antibiotics that may follow.

The prevalence of penicillin allergy labeling ranged from 0.9% to 10.2% across practices in a large pediatric cohort, raising questions regarding the validity of those labels and the unnecessary use of second-line antibiotics that may follow.

M-A: Most patients with allergy to Penicillin can be given Cefazolin

Systematic review: Safety and efficacy of de-labelling penicillin allergy in adults using direct oral challenge

Penicillin allergy labels increase second-line broad-spectrum antibiotic prescribing for pediatric respiratory tract infections

Podcast: A Clinical Pharmacologist’s Perspective on Penicillin Allergy

Study: Development and Validation of a Penicillin Allergy Clinical Decision Rule

Management of a surgical patient with a label of penicillin allergy: narrative review and consensus recommendations – British Journal of Anaesthesia

NICE: Double Check Patients with ‘Penicillin Allergy’ to Avoid Increased MRSA Risk

Cohort Study: Risk of Meticillin Resistant Staphylococcus Aureus and Clostridium Difficile in Patients with a Documented Penicillin Allergy

 

Estudo randomizado | Sulopeném (tem formulações oral e IV) não atingiu os critérios para não inferioridade em comparação ao ertapeném no tratamento de infecções complicadas de trato urinário, incluindo pielonefrite.

12 Set, 2022 | 11:27h

Sulopenem For The Treatment of Complicated Urinary Tract Infection Including Pyelonephritis: A Phase 3 Randomized Trial – Clinical Infectious Diseases

 

Endocardite infecciosa pediátrica: revisão de literatura.

12 Set, 2022 | 11:19h

Pediatric Infective Endocarditis: A Literature Review – Journal of Clinical Medicine

 

Revisão sistemática | Probióticos na prevenção de infecções agudas do trato respiratório superior.

8 Set, 2022 | 14:05h

Probiotics for preventing acute upper respiratory tract infections – Cochrane Library

 

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