Geriatria
Anticoagulantes e agentes para diabetes estão entre as causas mais frequentes de entrada nos departamentos de emergência atribuídas a danos farmacológicos.
27 Out, 2021 | 12:25hUS Emergency Department Visits Attributed to Medication Harms, 2017-2019 – JAMA (link para o resumo – $ para o texto completo)
Comentários:
Number of emergency room visits for medication harms increases with age – MedicalResearch.com
Blood thinners, diabetes meds among top causes of drug-related ER visits – UPI
Estudo randomizado por cluster | Aumentar as fontes dietéticas de cálcio e proteína (adicionando leite, iogurte e queijo) reduziu as fraturas de quadril e quedas em idosos em casas de repouso.
22 Out, 2021 | 12:19hComunicado de imprensa: Increasing dairy intake reduces falls and fractures among older care home residents – British Medical Journal
Comentário no Twitter
Increasing intake of foods rich in calcium and protein such as milk, yoghurt, and cheese, reduces falls and fractures in older adults living in residential care, finds a randomised controlled trial published @bmj_latest today https://t.co/QzozG4Odjb
— BMJ (@bmj_company) October 21, 2021
Estudo randomizado | Mirtazapina não é melhor que placebo para tratar a agitação em pessoas com demência e possivelmente esteve associada a mortalidade aumentada (7 mortes vs. 1, diferença não estatisticamente significativa, p = 0,065).
22 Out, 2021 | 12:17hComentário: Common antidepressant should no longer be used to treat people with dementia – University of Exeter
Revisão sistemática | Má nutrição em adultos internados.
22 Out, 2021 | 12:13hMalnutrition in Hospitalized Adults – Agency for Healthcare Research and Quality
Ver também:
Amplo estudo observacional sugere que o tramadol está associado a risco aumentado de desfechos adversos em comparação à codeína.
20 Out, 2021 | 11:54h(gratuito por tempo limitado)
Editorial: (gratuito por tempo limitado)
Conteúdo relacionado:
Estudo de coorte | Retenção urinária aguda pode ser um marcador clínico de câncer de próstata oculto e outras neoplasias urogenitais, colorretais e neurológicas.
20 Out, 2021 | 11:45hAcute urinary retention and risk of cancer: population based Danish cohort study – The BMJ
Comentário no Twitter
This study finds that a first diagnosis of acute urinary retention in patients aged 50 years or older was a clinical marker not only for prostate cancer but also for other urogenital cancers and colorectal and neurological cancershttps://t.co/0f1Z93cqR0 @dceaarhus
— The BMJ (@bmj_latest) October 19, 2021
Mais um estudo observacional sugere que rivaroxabam está associado com taxas mais altas de sangramento gastrintestinal do que outros anticoagulantes orais diretos (DOACs).
19 Out, 2021 | 12:44hRivaroxaban Is Associated with Higher Rates of Gastrointestinal Bleeding Than Other Direct Oral Anticoagulants: A Nationwide Propensity Score–Weighted Study – Annals of Internal Medicine (link para o resumo – $ para o texto completo)
Comentário: Rivaroxaban Again Linked to More Bleeding vs Other DOACs – TCTMD
Conteúdo relacionado: Gastrointestinal Safety of Direct Oral Anticoagulants: A Large Population-Based Study – Gastroenterology
Comentário no Twitter
A new study from @uni_iceland and @Landspitali finds that #Rivaroxaban is associated with a higher risk of GI bleeding compared to other direct oral anticoagulants. https://t.co/2J451CN5dD #afib #bleedingrisk #DOAC pic.twitter.com/Q6VSv5Taqg
— Annals of Int Med (@AnnalsofIM) October 13, 2021
M-A | Efetividade e segurança de tratamento com anti-inflamatórios não hormonais e opioides para osteoartrite de quadril e joelho – Embora etoricoxibe 60 mg/dia e diclofenaco 150 mg/dia pareçam ser os tratamentos mais efetivos, diclofenaco tópico 70 a 81 mg/dia é mais seguro e deveria ser considerado a primeira linha de tratamento.
18 Out, 2021 | 08:39hComunicado de imprensa: Topical pain-killers more effective, safer than opioids for knee osteoarthritis pain – St. Michael’s Hospital
Comentário: Network meta-analysis compares analgesic regimens for osteoarthritis – medwire News
Comentário no Twitter
Etoricoxib 60 mg/day and diclofenac 150 mg/day seem to be the most effective oral NSAIDs for knee and hip osteoarthritis pain and physical function, but might not be appropriate in the presence of comorbidities or for long term use, concludes #BMJResearchhttps://t.co/rrtX3BnQE5
— The BMJ (@bmj_latest) October 16, 2021
OMS fornece orientação direcionada para a falta de serviços de cuidados paliativos.
14 Out, 2021 | 10:47hComunicado de imprensa: WHO takes steps to address glaring shortage of quality palliative care services – World Health Organization
Ver Diretriz:
Comentário no Twitter (fio – clique para saber mais)
Today is World Hospice and Palliative Care Day!
DYK❓ Over 5⃣5⃣ million people around the 🌐 are in need of #PalliativeCare but only 12% of the global need is met.
Access to palliative care services is a human right to health 👉https://t.co/MebmzEstql pic.twitter.com/WQ3d40dH6d
— World Health Organization (WHO) (@WHO) October 9, 2021
Diretriz preliminar da USPSTF revisa a diretriz anterior e agora recomenda contra iniciar aspirina em baixa dose como prevenção primária de doença cardiovascular (DCV) em pessoas com 60 anos de idade ou mais.
13 Out, 2021 | 13:25hComentários:
Advice shifting on aspirin use for preventing heart attacks – Associated Press
Taking aspirin to prevent heart attack may cause more harm than good, task force says – NPR
Estudos randomizados relacionados:
Randomized Trial: Aspirin for Primary Prevention of Cardiovascular Disease
Randomized Trial: Effects of Aspirin for Primary Prevention in Persons with Diabetes
Randomized Trial: Effect of Aspirin on All-Cause Mortality in the Healthy Elderly
Metanálises relacionadas:
Meta-Analysis: Efficacy and Safety of Aspirin for Primary Prevention of Cardiovascular Events
Opiniões relacionadas:
Aspirin for Primary Prevention: Is This the End of the Road?
Evidence evolving on aspirin as prevention – ACP Internist
Comentário no Twitter
Low Dose Aspirin in the Primary Prevention of Cardiovascular Disease: #USPSTF recommends individualized decision making between 50 and 59 years, and against aspirin use in 60 years+. What a difference a few years can make, with more data and evidence. https://t.co/3nC3jpjTDq pic.twitter.com/SN8K3Z9XJj
— Muin J. Khoury (@MuinJKhoury) October 12, 2021