Acesso livre
Acesso livre

Endocrinologia

Estudo randomizado | Inibidores de SGLT2 reduzem o risco de hiperpotassemia em pacientes com diabetes e doença renal crônica.

24 Ago, 2021 | 11:36h

Effects of canagliflozin on serum potassium in people with diabetes and chronic kidney disease: the CREDENCE trial – European Heart Journal (link para o resumo – $ para o texto completo)

 

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Diretriz ACOG | Prevenção, rastreamento e diagnóstico de osteoporose.

23 Ago, 2021 | 13:05h

Osteoporosis Prevention, Screening, and Diagnosis: ACOG Clinical Practice Guideline No. 1 – Obstetrics & Gynecology


M-A | Agonistas receptores de GLP-1 reduzem eventos cardiovasculares adversos maiores, mortalidade por todas as causas, admissão hospitalar por insuficiência cardíaca e piora na função renal em pacientes com diabetes tipo 2.

23 Ago, 2021 | 12:58h

Cardiovascular, mortality, and kidney outcomes with GLP-1 receptor agonists in patients with type 2 diabetes: a systematic review and meta-analysis of randomised trials – The Lancet Diabetes & Endocrinology (link para o resumo – $ para o texto completo)

Conteúdo relacionado: Guideline: SGLT-2 inhibitors or GLP-1 receptor agonists for adults with type 2 diabetes – This guidance recommends a risk-based approach, advising against starting SGLT-2 inhibitors or GLP-1 receptor agonists in patients with three or fewer cardiovascular risk factors and without established CVD or CKD.


M-A | O papel dos inibidores de SGLT2 na insuficiência cardíaca.

23 Ago, 2021 | 12:56h

The Role of SGLT2 Inhibitors in Heart Failure: A Systematic Review and Meta-Analysis – Cardiology Research and Practice

Conteúdos relacionados:

ESC Position Paper: Cardiac, renal, and metabolic effects of SGLT2 inhibitors.

Guideline: SGLT-2 inhibitors or GLP-1 receptor agonists for adults with type 2 diabetes – This guidance recommends a risk-based approach, advising against starting SGLT-2 inhibitors or GLP-1 receptor agonists in patients with three or fewer cardiovascular risk factors and without established CVD or CKD.

Summary: SGLT2 inhibitors and GLP-1 receptor agonists established and emerging indications.

M-A: SGLT2 inhibitors decrease cardiovascular death and heart failure hospitalizations in patients with heart failure.

Meta-analysis: Association of SGLT2 inhibitors with cardiovascular and kidney outcomes in patients with Type 2 diabetes

#ESCCongress – [Abstract Only] SGLT2 inhibitors in patients with heart failure with reduced ejection fraction: A meta-analysis of the EMPEROR-Reduced and DAPA-HF trials

[Abstract Only] Randomized Trial: SGLT2 Inhibitor Improves Outcomes in Patients with Heart Failure Even in the Absence of Diabetes


Estudo de coorte | Desfechos cardiovasculares e renais dentro do espectro glicêmico – Pré-diabetes e diabetes tipo 2 foram independentemente associados a doença cardiovascular aterosclerótica.

18 Ago, 2021 | 12:35h

Cardiovascular and Kidney Outcomes Across the Glycemic Spectrum: Insights From the UK Biobank – Journal of the American College of Cardiology

Comentário: Cardiovascular and Kidney Outcomes in Diabetes and Prediabetes – American College of Cardiology


Revisão | Prevenção das complicações microvasculares do diabetes.

18 Ago, 2021 | 12:31h

Prevention of Microvascular Complications of Diabetes – Endocrinology and Metabolism Clinics of North America


Diabetes tipo 2: mais de 1 tipo de dieta pode ajudar os pacientes a atingirem a remissão da doença.

18 Ago, 2021 | 12:30h

Type 2 diabetes: more than one type of diet can help people achieve remission – The Conversation

Artigo original: Dietary strategies for remission of type 2 diabetes: A narrative review – Journal of Human Nutrition and Dietetics (link para o resumo – $ para o texto completo)


Estudo randomizado | Tirzepatida 1 vez/semana vs. insulina degludec 1 vez/dia em adição à metformina com ou sem inibidores de SGLT2 em pacientes com diabetes tipo 2.

17 Ago, 2021 | 11:23h

Once-weekly tirzepatide versus once-daily insulin degludec as add-on to metformin with or without SGLT2 inhibitors in patients with type 2 diabetes (SURPASS-3): a randomised, open-label, parallel-group, phase 3 trial – The Lancet (link para o resumo – $ para o texto completo)

Conteúdos relacionados:

RCT: Efficacy and safety of a novel dual GIP and GLP-1 receptor agonist tirzepatide in patients with type 2.

RCT: Tirzepatide yielded greater glycated hemoglobin and body weight reductions compared to Semaglutide 1 mg.


Estudo | Metabolismo tem pico mais precoce e começa a desacelerar mais tarde do que se pensava.

16 Ago, 2021 | 11:39h

Metabolism peaks much earlier and starts to decline later than you might think – News Medical

Estudo original: Daily energy expenditure through the human life course – Science (link para o resumo – $ para o texto completo)

 

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Estudo americano | Alimentos ultraprocessados compõem 2/3 das calorias da dieta de crianças e adolescentes.

16 Ago, 2021 | 11:37h

Trends in Consumption of Ultraprocessed Foods Among US Youths Aged 2-19 Years, 1999-2018 – JAMA (gratuito por tempo limitado)

Editorial: Intake of Ultraprocessed Foods Among US Youths: Health Concerns and Opportunities for Research and Policy (gratuito por tempo limitado)

Comunicado de imprensa: Ultraprocessed Foods Now Comprise 2/3 of Calories in Children and Teen Diets – Tufts University

Comentários:

Ultra-processed foods now account for two-thirds of calories in the diets of children and teens – CNN

If You Think Kids Are Eating Mostly Junk Food, A New Study Finds You’re Right – NPR

Conteúdos relacionados:

Ultra-processing is the new frontier in public health policy—reflections on the National Food Strategy – The BMJ Opinion

Cohort Study: Association Between Consumption of Ultra-processed Foods and All Cause Mortality

Study: Association Between Ultraprocessed Food Consumption and Risk of Mortality Among Middle-aged Adults

Research: Consumption of Ultra-Processed Foods and Cancer Risk

Randomized Trial: Ultra-Processed Diets Cause Excess Calorie Intake and Weight Gain

Ultra-Processed Foods and Incident Cardiovascular Disease in the Framingham Offspring Study

Cohort study: Higher intake of ultra-processed food linked to increased risk of inflammatory bowel disease.

 

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