Endocrinologia

Estudo de coorte | Depois de um episódio de hipoglicemia grave em idosos diabéticos, o tratamento com sulfonilureias ou insulina teve sua intensidade reduzida em menos de 50% dos episódios.

12 Nov, 2021 | 13:25h

Deintensification of Treatment With Sulfonylurea and Insulin After Severe Hypoglycemia Among Older Adults With Diabetes – JAMA Network Open

 

Comentário no Twitter

Less than half of older adults with diabetes seen in the ED or hospitalized for hypoglycemia had high-risk medications (sulfonylureas or insulin) deintensified in the following 100 days, although deintensification rates may be increasing over time. https://t.co/X0TAbUxcIh

— JAMA Network Open (@JAMANetworkOpen) November 2, 2021

 

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Estudo de coorte | Entre idosos diabéticos internados para tratamento de condições médicas comuns, a intensificação das medicações para diabetes na alta hospitalar foi associada com risco aumentado, no curto prazo, de eventos hipoglicêmicos graves, mas não foi associada com melhora no controle glicêmico.

12 Nov, 2021 | 13:24h

Intensification of Diabetes Medications at Hospital Discharge and Clinical Outcomes in Older Adults in the Veterans Administration Health System – JAMA Network Open

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M-A | Baixos níveis de vitamina D não agravam o risco de infecção ou morte por COVID-19, e a suplementação de vitamina D não melhora os desfechos em pacientes internados com COVID-19.

11 Nov, 2021 | 16:18h

Low vitamin D levels do not aggravate COVID-19 risk or death, and vitamin D supplementation does not improve outcomes in hospitalized patients with COVID-19: a meta-analysis and GRADE assessment of cohort studies and RCTs – Nutritional Journal

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Choosing Wisely para doenças da tireoide: dez coisas que médicos e pacientes deveriam perguntar – “Não solicitar ultrassonografia de tireoide para detecção de nódulos em pacientes sem anomalias anatômicas da tireoide no exame clínico.”

9 Nov, 2021 | 12:08h

Choosing Wisely for Thyroid Conditions: Recommendations of the Thyroid Department of the Brazilian Society of Endocrinology and Metabolism

Ver lista completa de práticas de baixo valor: Choosing Wisely U.S. / Choosing Wisely UK / Choosing Wisely Australia E Choosing Wisely Canada

 

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Diretriz preliminar NICE recomenda o uso do inibidor de SGLT2 dapagliflozina para alguns pacientes com doença renal crônica.

8 Nov, 2021 | 12:28h

NICE recommend dapagliflozin for people with chronic kidney disease – National Institute for Health and Care Excellence

Ver diretriz preliminar:

Appraisal consultation document (online commenting)

Appraisal consultation document (PDF version)

Conteúdos relacionados:

NICE Guideline: Assessment and management of chronic kidney disease.

Secondary analysis of RCT finds Dapagliflozin is safe for patients with stage 4 chronic kidney disease.

Randomized trial: Dapagliflozin in patients with chronic kidney disease

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Cuidados clínicos na estratificação de risco e tratamento de pacientes com doença hepática gordurosa não alcoólica.

5 Nov, 2021 | 17:12h

Clinical Care Pathway for the Risk Stratification and Management of Patients With Nonalcoholic Fatty Liver Disease – Gastroenterology

Comunicado de imprensa: International experts develop Clinical Care Pathway in response to NASH epidemic – American Gastroenterology Association

Conteúdos relacionados:

Non-alcoholic fatty liver disease: A patient guideline.

State of the art review: Management of non-alcoholic fatty liver disease

M-A: Non-alcoholic fatty liver disease linked to increased risk of fatal and non-fatal cardiovascular events.

M-A: non-invasive tests for advanced fibrosis can reduce the need for biopsy in patients with non-alcoholic fatty liver disease.

Review: Dietary carbohydrates and fats in nonalcoholic fatty liver disease.

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Revisão | Dietas com menos carboidratos para adultos com diabetes tipo 2.

4 Nov, 2021 | 11:55h

Lower carbohydrate diets for adults with type 2 diabetes – British Journal of Nutrition

Conteúdos relacionados:

Meta-analysis of randomized trials: patients adhering to a low carbohydrate diet for six months may experience remission of diabetes without adverse consequences

Low carbohydrate diet: Insights from a general practice service in patients with type 2 diabetes

Position Statement on Low-Carbohydrate Diets for Adults with Diabetes

Low Carbohydrate Diets for Diabetes: A Review of the Clinical Effectiveness and Guidelines

Systematic Review: Low‐carbohydrate Diets for Type 2 Diabetes Management

Practical Guide: Adapting Diabetes Medication for Low Carbohydrate Management of Type 2 Diabetes

Observational Study: Management of Type 1 Diabetes With a Very Low–Carbohydrate Diet

Study: Dietary Carbohydrate Restriction Improves Metabolic Syndrome Independent of Weight Loss

Research: Carbohydrate-last meal pattern lowers postprandial glucose and insulin excursions in type 2 diabetes

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Diretriz Científica AHA | Guia de orientação nutricional 2021 para melhorar a saúde cardiovascular.

3 Nov, 2021 | 11:09h

2021 Dietary Guidance to Improve Cardiovascular Health: A Scientific Statement From the American Heart Association – Circulation

Comunicado de imprensa: New look at nutrition research identifies 10 features of a heart-healthy eating pattern – American Heart Association

Principais tópicos a saber: 2021 Dietary Guidance to Improve Cardiovascular Health – American Heart Association

Comentários:

‘Balance’ is the key word in new dietary guidance for heart health – American Heart Association

The new American Heart Association dietary guidance to improve population-level cardiometabolic health: moving toward a heart-healthy food environment – American Heart Association

 

Comentário no Twitter

CHOOSE MINIMALLY PROCESSED FOODS INSTEAD OF ULTRA-PROCESSED FOODS is one of the 10 evidence-based dietary pattern recommendations in the new excellent 2021 American Heart Association Scientific Statement on Dietary Guidance to Improve Cardiovascular Healthhttps://t.co/YgtDKz05EP

— Carlos A. Monteiro (@CMonteiro_USP) November 2, 2021

 

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Revisão sistemática | Agonistas receptores de GLP-1 e inibidores de SGLT-2 parecem reduzir o risco de morte por doença cardiovascular e morte por qualquer causa em pessoas com diabetes e doença cardiovascular estabelecida.

29 Out, 2021 | 14:44h

Dipeptidyl peptidase‐4 inhibitors, glucagon‐like peptide 1 receptor agonists and sodium‐glucose co‐transporter‐2 inhibitors for people with cardiovascular disease: a network meta‐analysis – Cochrane Library

Resumo: The effects of DPP-4 inhibitors, GLP-1 receptor agonists and SGLT-2 inhibitors for people with cardiovascular disease – Cochrane Library

 

Comentário no Twitter

The effects of DPP‐4 inhibitors, GLP‐1 receptor agonists and SGLT‐2 inhibitors for people with #CardiovascularDisease https://t.co/0FwffSCqbC New @CochraneHeart network meta-analysis looks at evidence from 31 studies. #CardiovascularResearch

— The Cochrane Library (@CochraneLibrary) October 27, 2021

 

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Estudo randomizado | Em pacientes críticos, o controle individualizado da glicose, levando em conta o nível de glicemia do paciente antes da sua admissão em UTI, não demonstrou benefícios de sobrevida em comparação ao controle convencional (glicemia-alvo abaixo de 180 mg/dL).

27 Out, 2021 | 12:26h

Individualised versus conventional glucose control in critically-ill patients: the CONTROLING study—a randomized clinical trial – Intensive Care Medicine

Editorial: The goal of personalized glucose control in the critically ill remains elusive – Intensive Care Medicine

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