Acesso livre
Acesso livre

Emergências e Terapia Intensiva

Estudo randomizado | Efeito da antibioticoterapia inicial guiada por coloração de Gram sobre a resposta clínica de pacientes com pneumonia associada a ventilador.

12 Abr, 2022 | 12:35h

Effect of Gram Stain–Guided Initial Antibiotic Therapy on Clinical Response in Patients With Ventilator-Associated Pneumonia: The GRACE-VAP Randomized Clinical Trial – JAMA Network Open

Comentário: Can Gram Stains Guide Antibiotics for Pneumonia in Critical Care? – Medscape (necessário cadastro gratuito)

 

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Diretrizes NCCN | Toxicidades relacionadas a terapia com CAR T Cells em pacientes com câncer.

12 Abr, 2022 | 12:31h

Management of Immunotherapy-Related Toxicities, Version 1.2022, NCCN Clinical Practice Guidelines in Oncology – Journal of the National Comprehensive Cancer Network

Conteúdos relacionados:

Reviews: CAR T-Cell Therapy Toxicities and Side Effects

Reviews: CAR T-Cell Therapy Toxicities and Side Effects

Critical Care Management of Chimeric Antigen Receptor T Cell–related Toxicity. Be Aware and Prepared

Reviews: CAR T-Cell Therapy Toxicities and Side Effects


M-A | Metas de oxigênio durante a ventilação mecânica na UTI.

12 Abr, 2022 | 12:20h

Oxygen Targets During Mechanical Ventilation in the ICU: A Systematic Review and Meta-Analysis – Critical Care Explorations


M-A | Terapias profiláticas para morbidade e mortalidade após hemorragia subaracnóidea aneurismática.

12 Abr, 2022 | 12:11h

Prophylactic Therapies for Morbidity and Mortality After Aneurysmal Subarachnoid Hemorrhage: A Systematic Review and Network Meta-Analysis of Randomized Trials – Stroke (link para o resumo – $ para o texto completo)

Conteúdo relacionado: RCT: Effects of clazosentan on cerebral vasospasm–related morbidity and all-cause mortality after aneurysmal subarachnoid hemorrhage.

 

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M-A | Avaliação do risco no ambiente pré-hospitalar em pacientes com suspeita de síndrome coronariana aguda sem elevação do segmento ST.

12 Abr, 2022 | 11:55h

Prehospital risk assessment in patients suspected of non-ST-segment elevation acute coronary syndrome: a systematic review and meta-analysis – BMJ Open

 

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Estudo randomizado | Em crianças criticamente doentes que necessitam de suporte respiratório não invasivo após extubação, a cânula nasal de alto fluxo NÃO foi não inferior ao CPAP, resultando em maior tempo de liberação do suporte respiratório.

11 Abr, 2022 | 13:07h

Effect of High-Flow Nasal Cannula Therapy vs Continuous Positive Airway Pressure Following Extubation on Liberation From Respiratory Support in Critically Ill Children: A Randomized Clinical Trial – JAMA (gratuito por tempo limitado)

Editorial: Selecting Intermediate Respiratory Support Following Extubation in the Pediatric Intensive Care Unit – JAMA (gratuito por tempo limitado)

Comunicado de imprensa: Trial identifies most effective breathing support for children in intensive care – Imperial College London

 

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Revisão do estado de arte | Prognóstico e tomada de decisão compartilhada no cuidado neurocrítico.

11 Abr, 2022 | 13:02h

Prognostication and shared decision making in neurocritical care – The BMJ

 

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M-A | Padrões de trombose e desfecho clínico da trombocitopenia trombótica imune induzida por vacina contra COVID-19.

11 Abr, 2022 | 12:58h

Thrombosis patterns and clinical outcome of COVID-19 vaccine-induced immune thrombotic thrombocytopenia: A Systematic Review and Meta-Analysis – International Journal of Infectious Diseases

Conteúdos relacionados:

Case series of Thrombosis with Thrombocytopenia Syndrome after Covid-19 vaccination in the US.

Review: Vaccine-induced immune thrombotic thrombocytopenia.

Vaccine induced immune thrombocytopenia and thrombosis: summary of NICE guidance.

Clinical features of vaccine-induced immune thrombocytopenia and thrombosis.

Review: Clinical characteristics and pharmacological management of COVID-19 vaccine–induced immune thrombotic thrombocytopenia with cerebral venous sinus thrombosis.

Vaccine-induced immune thrombotic thrombocytopenia: what we know and do not know.

Very rare cases of thrombosis with thrombocytopenia syndrome (TTS) after AstraZeneca vaccine: a global safety database analysis – the estimated rate of TTS after the first dose was 8.1 per million vaccinees; after the second dose, the estimated rate was 2.3 per million vaccinees. (vários artigos e fontes sobre o tema)


M-A | Desempenho diagnóstico do CO-RADS para Covid-19.

11 Abr, 2022 | 12:53h

Diagnostic performance of CO-RADS for COVID-19: a systematic review and meta-analysis – European Radiology

Conteúdos relacionados: CO-RADS – A categorical CT assessment scheme for patients with suspected COVID-19: definition and evaluation – Radiology


AVC: avanços no tratamento dão esperança ao pacientes.

11 Abr, 2022 | 12:50h

Stroke: advances in treatment offer hope for patients – Evidently Cochrane


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