Covid-19 (Temas de Saúde Pública)

Nova análise do Global Burden of Disease Study mostra depressão e ansiedade entre as principais causas mundiais de impacto de saúde, além de um aumento significativo decorrente da pandemia de COVID-19.

12 Out, 2021 | 11:24h

Comunicado de imprensa: New Global Burden of Disease analyses show depression and anxiety among the top causes of health burden worldwide, and a significant increase due to the COVID-19 pandemic – Institute for Health Metrics and Evaluation

Estudo original: Global prevalence and burden of depressive and anxiety disorders in 204 countries and territories in 2020 due to the COVID-19 pandemic – The Lancet

Comentários:

Depression and anxiety disorders during the COVID-19 pandemic: knowns and unknowns – The Lancet

COVID-19 pandemic led to stark rise in depressive and anxiety disorders globally in 2020: study – The Lancet

Covid crisis dramatically worsened global mental health, study finds – The Guardian

 

Comentário no Twitter (fio – clique para saber mais)

✨🆕–The #COVID19 pandemic led to a stark rise in depressive and anxiety disorders globally in 2020 w/women & younger people most affected, according to a new study by our researchers & collaborators published today in @TheLancet. #GBDstudy #MentalHealth

»https://t.co/qXEDzn3idV pic.twitter.com/4xsofBXyvS

— Institute for Health Metrics and Evaluation (IHME) (@IHME_UW) October 8, 2021

 

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Crianças estão perdendo dias de aula para a quarentena. Há um meio de mantê-las nas aulas – “Realizar testes frequentes poderia reduzir drasticamente a quarentena de contatos próximos.”

12 Out, 2021 | 11:20h

Kids are losing school days to quarantines. Here’s a way to keep them in classrooms – NPR

Estudo relacionado: Cluster RCT: Daily contact testing of school-based contacts was non-inferior to self-isolation for control of COVID-19 transmission.

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[Preprint] COVID-19 em crianças, decorrente da cepa Delta do SARS-CoV-2, é semelhante à doença causada pela variante Alfa, com curta duração e sintomas similares.

12 Out, 2021 | 11:16h

Illness characteristics of COVID-19 in children infected with the SARS-CoV-2 Delta variant – medRxiv

 

Comentário no Twitter

Did you hear “Delta is different”, when it comes to #COVID19 symptom severity in children?

GOOD NEWS 🥳

Turns out there is barely any difference at all between Delta and Alpha in symptom duration, severity, or risk of “long covid”

Myth busted 💥 https://t.co/iPd9AedXaS

— Alasdair Munro (@apsmunro) October 7, 2021

 

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É muito baixo o risco de inflamação cardíaca após vacina da Pfizer contra COVID.

12 Out, 2021 | 11:15h

Heart-inflammation risk from Pfizer COVID vaccine is very low – Nature

Estudos originais:

Large cohort study with over 2.5 million individuals showed the incidence of myocarditis after the Pfizer vaccine was 2.13 cases per 100,000 persons.

Study with over 5.1 million vaccinated individuals showed the incidence of myocarditis after the receipt of the Pfizer vaccine was low and more common after the second dose in young male recipients.

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Diretriz OMS | Detecção por antígeno no diagnóstico da infecção por SARS-CoV-2.

8 Out, 2021 | 12:33h

Antigen-detection in the diagnosis of SARS-CoV-2 infection – World Health Organization

Infográficos relacionados:

Use of antigen detection rapid diagnostic testing – World Health Organization

Diagnostic testing for SARS-CoV-2 infection – World Health Organization

 

Comentário no Twitter (fio – clique para saber mais)

Testing remains a critical component to the strategy to end the #COVID19 pandemic, and testing needs to be reliable, accessible, affordable, fast and linked to public health action.

So many around 🌍 have worked hard to increase testing capacities @WHOhttps://t.co/VDPdU0VK4g

— Maria Van Kerkhove (@mvankerkhove) October 7, 2021

 

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Consenso OMS | Definição de caso clínico da condição pós-COVID-19 (“long Covid”).

8 Out, 2021 | 12:31h

A clinical case definition of post COVID-19 condition by a Delphi consensus, 6 October 2021 – World Health Organization

Conteúdos relacionados:

Characterizing long COVID: a living systematic review.

Long Covid – The illness narratives.

New guidelines to help doctors manage long COVID patients published.

M-A: More than 50 long-term effects of COVID-19. (vários artigos sobre o tema)

 

Comentário no Twitter (fio – clique para saber mais)

🆕 WHO clinical case definition for post #COVID19 condition, also called 'long COVID' https://t.co/WoiLcwsgJX pic.twitter.com/Z0olrHlWPC

— World Health Organization (WHO) (@WHO) October 7, 2021

 

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OMS lança estratégia para atingir a vacinação global contra Covid-19 até meados de 2022.

8 Out, 2021 | 12:28h

Strategy to Achieve Global Covid-19 Vaccination by mid-2022 – World Health Organization

Comunicado de imprensa: WHO, UN set out steps to meet world COVID vaccination targets – World Health Organization

Comentários:

WHO Believes 70% Vaccination Target is Possible – But Only if Wealthy Countries Make Way for COVAX and Africa – Health Policy Watch

WHO launches global COVID vaccination strategy – CIDRAP

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Estudo mostra risco aumentado de síndrome de Guillain-Barré após vacina da J&J; a razão de taxas foi de 4,18 para uma janela de 42 dias.

8 Out, 2021 | 12:27h

Association of Receipt of the Ad26.COV2.S COVID-19 Vaccine With Presumptive Guillain-Barré Syndrome, February-July 2021 – JAMA

 

Comentário no Twitter

Study suggests a potential small but statistically significant safety concern for #GuillainBarré syndrome following receipt of the @JanssenUS #COVID19 vaccine; findings considered preliminary pending analysis of medical records to establish a definitive Dx https://t.co/yZjJVkp6BA

— JAMA (@JAMA_current) October 7, 2021

 

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Dados de mundo real mostram reatogenicidade aumentada em adultos após vacinação heteróloga em comparação à homóloga contra COVID-19.

8 Out, 2021 | 12:25h

Real-world data shows increased reactogenicity in adults after heterologous compared to homologous prime-boost COVID-19 vaccination, March−June 2021, England – Eurosurveillance

Conteúdos relacionados:

RCT: Safety and immunogenicity of heterologous vs. homologous prime-boost schedules with an adenoviral vectored and mRNA COVID-19 vaccine.

Another study shows increased immune response with heterologous Oxford-AstraZeneca/mRNA vaccination.

Heterologous Oxford–AstraZeneca and Moderna Vaccination induce increased levels of neutralizing antibody compared to 2 doses of Oxford–AstraZeneca.

Heterologous Oxford–AstraZeneca and BioNTech/Pfizer Vaccination induce increased levels of neutralizing antibody compared to 2 doses of Oxford–AstraZeneca.

[Preprint] Mixing Covid jabs has good immune response, study finds – “The Com-Cov trial looked at the efficacy of either two doses of Pfizer, two of AstraZeneca, or one of them followed by the other. All combinations worked well, priming the immune system”.

Phase 2 RCT: Immunogenicity and reactogenicity of a Pfizer-BioNTech booster in patients that have received a single dose of AstraZeneca vaccine – “BNT162b2 (Pfizer) given as a second dose in individuals prime vaccinated with ChAdOx1-S (AstraZeneca) induced a robust immune response, with an acceptable and manageable reactogenicity profile”.

Lab study shows heterologous AstraZeneca/Pfizer vaccination produces strong immune response against SARS-CoV-2 Delta variant.

Lab study shows a heterologous AstraZeneca + Pfizer immunization strategy provides stronger immunogenicity against Covid compared to homologous AZ + AZ or Pfizer + Pfizer strategies.

RCT: Mixing 2 different Covid vaccines is associated with increased risk of side effects.

 

Comentário no Twitter

As more & more countries consider adding a 3rd #COVID19 vaccine dose into their national immunisation programmes, vaccine reactogenicity will become important, especially if 3rd dose is different to first 2 doses. We need more mix-n-match booster studies 👉https://t.co/G57i9Ej7Nd

— Shamez Ladhani (@ShamezLadhani) October 7, 2021

 

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Como o risco de Covid-19 em crianças se compara a outros perigos.

8 Out, 2021 | 12:23h

How the risk of Covid-19 for kids compares to other dangers – Vox

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