Acesso livre
Acesso livre

Covid-19 (Temas de Saúde Pública)

Estudo observacional mostrou que a vacina de dose única da J&J teve efetividade de 74% contra Covid-19 sintomática.

4 Nov, 2021 | 12:07h

Analysis of the Effectiveness of the Ad26.COV2.S Adenoviral Vector Vaccine for Preventing COVID-19 – JAMA Network Open

Comentários:

Single-Dose Ad26.COV2.S Vaccine—Room for Improvement – JAMA Network Open

Real-world study shows J&J COVID-19 vaccine 74% effective – CIDRAP

Conteúdos relacionados:

J&J COVID-19 Vaccine: FDA recommends booster shot for all adults aged 18 and older at least two months following initial vaccination with the single-shot vaccine.

[Press release – not published yet] J&J says booster shot at two months provided 75% protection against moderate to severe COVID-19 globally and 94% of such cases in the U.S.

CDC Report: Moderna’s vaccine associated with greater effectiveness (93%) against Covid-19 hospitalization compared to Pfizer (88%) and J&J (71%) vaccines.

[Preprint] Observational study finds single-dose Johnson & Johnson vaccine is 76.7% effective in preventing SARS-CoV-2 infection

RCT: Single-Dose Johnson & Johnson Vaccine has 85% efficacy against severe/critical Covid-19 and maintains efficacy against variant B.1.351

Diretriz do CDC | Pessoas imunocomprometidas podem precisar de uma quarta dose de vacina contra Covid-19.

4 Nov, 2021 | 12:05h

Interim Clinical Considerations for Use of COVID-19 Vaccines Currently Approved or Authorized in the United States – Centers for Disease Control and Prevention

Comentários:

Immunocompromised may need a fourth Covid-19 shot, CDC says – CNN

Some immunocompromised people can receive a 4th Covid shot, CDC says – NBC News

Conselho do CDC endossa a vacina da Pfizer contra Covid-19 para crianças de 5 a 11 anos.

3 Nov, 2021 | 11:18h

Slides da apresentação do ACIP: November 2-3, 2021 Meeting – Centers for Disease Control and Prevention

Comentários:

CDC advisors give go-ahead to COVID-19 vaccines for young kids – CIDRAP

CDC advisers endorse Pfizer’s Covid-19 vaccine for kids 5-11 – STAT

American Academy of Pediatrics Applauds CDC Advisory Committee’s Approval of Safe, Effective COVID-19 Vaccine for Children Ages 5-11

Vacinação contra COVID-19 na gestação – Número necessário para vacinar e evitar danos.

3 Nov, 2021 | 11:16h

COVID-19 vaccination in pregnancy—number needed to vaccinate to avoid harm – The Lancet Infectious Diseases

Conteúdos relacionados:

A case-controlled study showed Covid-19 vaccination during early pregnancy was not associated with increased risk of first-trimester miscarriage.

Editorial: Covid-19 treatments and vaccines must be evaluated in pregnancy.

AstraZeneca vaccination not linked to reduced fertility rates and adverse birth outcomes.

Cohort study: Vaccinated pregnant patients had 90% lower risk of severe or critical Covid-19 compared with unvaccinated pregnant patients.

Two observational studies suggest spontaneous abortion is not increased following COVID-19 mRNA vaccination during pregnancy.

Study shows high effectiveness of the Pfizer mRNA COVID-19 vaccine in pregnancy.

5 Crucial Things to Know About COVID-19 Vaccines and Pregnancy.

CDC Guidance: Pregnant people should be vaccinated against COVID-19.

ACOG and SMFM Recommend COVID-19 Vaccination for Pregnant Individuals – “ACOG encourages its members to enthusiastically recommend vaccination to their patients.”

Cohort study: Pfizer/BioNTech COVID vaccine associated with 78% lower risk of Covid-19 in pregnancy.

Vacina da J&J contra Covid-19 está associada com risco aumentado de trombose de seio venoso cerebral.

2 Nov, 2021 | 12:36h

Age- and Sex-Specific Incidence of Cerebral Venous Sinus Thrombosis Associated With Ad26.COV2.S COVID-19 Vaccination – JAMA

Comentário: Cerebral Venous Sinus Thrombosis Rate Up After Ad26.COV2.S Shot – HealthDay

Mortes globais por Covid-19 ultrapassam os 5 milhões.

2 Nov, 2021 | 12:33h

Global Covid-19 deaths surpass five million – CNN

Ver também:

The COVID-19 pandemic has now killed 5 million people around the world – NPR

G20 leaders back COVID measures as deaths top 5 million – CIDRAP

Covid-19 deaths pass five million worldwide – BBC

Conteúdos relacionados:

Under-reporting of deaths limits our understanding of true burden of covid-19.

Study shows COVID-19 has caused the biggest decrease in life expectancy since World War II.

Just how do deaths due to COVID-19 stack up?

Tracking excess mortality across countries during the COVID-19 pandemic with the World Mortality Dataset.

Exploring the gap between excess mortality and COVID-19 deaths in 67 countries.

Report: Three new estimates of India’s all-cause excess mortality during the COVID-19 Pandemic – pandemic death toll estimated to be between 3.4 million and 4.9 million excess deaths.

COVID-19 has caused 6.9 million deaths globally, more than double what official reports show

 

Comentário no Twitter

 

Mortes associadas a COVID-19 e síndrome inflamatória multissistêmica em crianças (multisystem inflammatory syndrome – MIS-C) entre crianças e adolescentes nos Estados Unidos.

2 Nov, 2021 | 12:31h

Deaths in Children and Adolescents Associated With COVID-19 and MIS-C in the United States – Pediatrics

Conteúdos relacionados:

Thirty-Day Outcomes of Children and Adolescents With COVID-19: An International Experience – “Despite negligible fatality, complications including hospitalization, hypoxemia, and pneumonia were more frequent in children and adolescents with COVID-19 than with influenza”.

Deaths from COVID ‘incredibly rare’ among children.

[Preprint] Study confirms children’s extremely low risk of death from Covid-19 – “99·995% of children and young people with a positive SARS-CoV-2 test survived”.

Estudo mostra que mesmo indivíduos plenamente vacinados ainda podem se infectar com a variante delta do SARS-CoV-2 e transmitir a doença em ambientes domiciliares, incluindo contactantes vacinados.

1 Nov, 2021 | 11:05h

Community transmission and viral load kinetics of the SARS-CoV-2 delta (B.1.617.2) variant in vaccinated and unvaccinated individuals in the UK: a prospective, longitudinal, cohort study – The Lancet Infectious Diseases

Comentários:

COVID vaccines effective but household transmission of delta a risk for 1 in 4 – Imperial College London

What is the vaccine effect on reducing transmission in the context of the SARS-CoV-2 delta variant? – The Lancet Infectious Diseases

CoVID-19 vaccines lower risk of infection with delta variant, but infection can still be passed on in household settings – the Lancet

COVID vaccines protect against Delta but don’t fully stop disease spread – CIDRAP

Covid: Double vaccinated can still spread virus at home – BBC

 

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Estudo observacional sugere que uma terceira dose da vacina da Pfizer contra COVID-19 pode prevenir desfechos graves relacionados à doença em comparação com somente duas doses tomadas pelo menos 5 meses antes.

1 Nov, 2021 | 11:03h

Effectiveness of a third dose of the BNT162b2 mRNA COVID-19 vaccine for preventing severe outcomes in Israel: an observational study – The Lancet

Comentário convidado: Boosters appear effective, but are they always needed? – The Lancet

 

Comentários no Twitter

 

Editorial | Segurança e eficácia de antivirais contra SARS-CoV-2 – “Precisamos de evidências, não de otimismo.”

1 Nov, 2021 | 11:02h

Safety and efficacy of antivirals against SARS-CoV-2 – The BMJ

 

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