Covid-19 (Temas de Saúde Pública)

Vaccines reduce the risk of long COVID by lowering the chances of contracting COVID-19. But studies suggest that vaccination might only halve the risk of long COVID, or have no effect on it at all, in a breakthrough infection. Read the @Nature report. https://t.co/MEkzXyO7hD

— Nature Portfolio (@NaturePortfolio) November 25, 2021

Aposta de Cuba nas vacinas contra COVID produzidas no país está valendo a pena.

25 Nov, 2021 | 15:11h

Cuba’s bet on home-grown COVID vaccines is paying off – Nature

OMS emite diretrizes sobre o tratamento de crianças com síndrome inflamatória multissistêmica associada a COVID-19.

24 Nov, 2021 | 11:37h

Comunicado de imprensa: WHO issues guidelines on the treatment of children with multisystem inflammatory syndrome associated with COVID-19 – World Health Organization

Diretriz: Living guidance for clinical management of COVID-19 – World Health Organziation

Conteúdos relacionados:

An Update on Multisystem Inflammatory Syndrome in Children Related to SARS-CoV-2.

Ten Things to Know About Multisystem Inflammatory Syndrome in Children (MIS-C).

Cohort study: long term follow-up showed most patients with post–COVID-19 Multisystem Inflammatory Syndrome in Children had good outcomes with no significant medium- or long-term sequelae.

Kawasaki Disease and Multisystem Inflammatory Syndrome in Children: An Overview and Comparison.

Cohort study: Six month follow-up of Multisystem Inflammatory Syndrome in Children.

Cohort study: Among children with Multisystem Inflammatory Syndrome (MIS-C) associated with Covid-19, there was no evidence that recovery differed after primary treatment with intravenous immune globulin (IVIG) alone, IVIG plus glucocorticoids, or glucocorticoids alone.

Cohort study: Among children with Multisystem Inflammatory Syndrome (MIS-C) associated with Covid-19, initial treatment with intravenous immune globulin (IVIG) plus glucocorticoids was associated with a lower risk of new or persistent cardiovascular dysfunction than IVIG alone.

Cohort study showed that the incidence of Multisystem Inflammatory Syndrome in Children (MIS-C) was 316 persons per 1 000 000 SARS-CoV-2 infections in persons younger than 21 years. The incidence was higher among Black, Hispanic or Latino, and Asian or Pacific Islander persons.

Cohort study showed good recovery for most children 6 months after Pediatric Inflammatory Multisystem Syndrome (PIMS-TS) associated with SARS-CoV-2.

Epidemiology of Multisystem Inflammatory Syndrome in Children: A Step Closer to Understanding Who, Where, and When

Neurologic involvement in children and adolescents with COVID-19 or Multisystem Inflammatory Syndrome

Clinical Update: Acute covid-19 and multisystem inflammatory syndrome in children

Differences in characteristics and outcomes of children and adolescents with Multisystem Inflammatory Syndrome in Children (MIS-C) vs. severe acute COVID-19

Cutaneous findings in SARS-CoV-2-associated Multisystem Inflammatory Disease in Children (MIS-C)

SR: Multisystem inflammatory syndrome in children related to COVID-19

Observational study: The combination of Immunoglobulins + Methylprednisolone was associated with a better course of fever compared to Immunoglobulins alone in Multisystem Inflammatory Syndrome in children

ACR Guidance for pediatric patients with multisystem inflammatory syndrome in children associated with SARS‐CoV‐2

New systematic review of Multisystem Inflammatory Syndrome in Children Associated With SARS-CoV-2 infection summarizes the clinical features, management, and outcomes of the disease, showing favorable outcomes for the majority of children

Opinião de 32 ministros de saúde: o mundo precisa agir agora e se preparar para futuras emergências de saúde.

24 Nov, 2021 | 11:36h

The world must act now to be prepared for future health emergencies – The BMJ

Conteúdos relacionados:

Viewpoint | Strengthening global health security and reforming the international health regulations: making the world safer from future pandemics.

Perspective | Learning from crisis: building resilient systems to combat future pandemics.

Systematic review: Border controls, restricted entry, quarantine essential for curbing COVID-19 and future pandemics.

Opinion | The future of pandemic preparedness: agile coordination around clinical trials.

UN Report: Preventing the Next Pandemic – Zoonotic Diseases and How to Break the Chain of Transmission

Comentário no Twitter

Solidarity is key to protect the world from pandemics. This call by over 30 governments for a #PandemicTreaty to prepare for & respond to pandemics shows collaboration at work. The upcoming #WHASpecial session is a historic opportunity to make the world safer. https://t.co/98TgPce03t

— Tedros Adhanom Ghebreyesus (@DrTedros) November 23, 2021

Promoção da aceitação das vacinas contra COVID-19: recomendações da comissão do Lancet sobre recusa de vacina, aceitação e demanda nos EUA.

24 Nov, 2021 | 11:32h

Promoting COVID-19 vaccine acceptance: recommendations from the Lancet Commission on Vaccine Refusal, Acceptance, and Demand in the USA – The Lancet

Conteúdo relacionado: WHO Guidance for improving acceptance and uptake of COVID-19 vaccines

[Preprint] Revisão sistemática | Duração da efetividade das vacinas contra infecção por SARS-CoV-2 e COVID-19 – “Na maioria dos estudos, a efetividade contra COVID-19 grave continua alta (>70%) após 6 meses de vacinação completa, embora de fato haja alguma queda (na média, 8 a 10 pontos percentuais) entre 1 e 6 meses depois da vacinação.”

23 Nov, 2021 | 15:55h

Duration of Effectiveness of Vaccines Against SARS-CoV-2 Infection and COVID-19 Disease: Results of a Systematic Review and Meta-Regression – Preprints with The Lancet – SSRN

Conteúdos relacionados:

Correlation of SARS-CoV-2-breakthrough infections to time-from-vaccine.

China’s COVID vaccines have been crucial — now immunity is waning.

[Preprint] Breakthrough SARS-CoV-2 infections in 620,000 U.S. Veterans, February 1, 2021 to August 13, 2021 – “Vaccine protection declined by mid-August 2021, decreasing from 91.9% in March to 53.9%”.

Observational study in Qatar showed the effectiveness of Pfizer vaccine against any SARS-CoV-2 infection dropped to 20% in months 5 through 7 after the second dose, but effectiveness against severe Covid-19 remained high.

Cohort study: Pfizer vaccine effectiveness against any infections declined from 88% during the first month after full vaccination to 47% after 5 months. Vaccine effectiveness against hospital admissions remained high; 87% within 1 month, and 88% at 5 months after full vaccination, with no significant waning.

Editorial | Covid-19 vaccination: evidence of waning immunity is overstated.

COVID vaccine immunity is waning — how much does that matter? – “As debates about booster shots heat up, what’s known about the duration of vaccine-based immunity is still evolving”.

COVID vaccine effects wane over time but still prevent death and severe illness.

Perspective | What we actually know about waning immunity.

Another study shows Pfizer mRNA vaccine immunity is reduced over time.

[Press release – not published yet] Study shows vaccine protection wanes over time, but vaccines still offer good protection against severe disease.

Studies: COVID vaccine protection waning against infection but not hospitalization.

Diretriz provisória da OMS sobre a vacinação de crianças e adolescentes contra a COVID-19.

Estudo de coorte baseado na população do Catar mostrou que as reinfecções tiveram 90% menos chances de resultar em internação ou morte do que as infecções primárias.

Reinfecção por COVID-19: o papel da imunidade natural, das vacinas e das variantes.

Perspectiva | Fabricantes de vacinas contra COVID-19 se planejam para os reforços anuais, mas não está claro se isso será necessário.

As vacinas protegem contra a “long COVID”? O que dizem os dados – “Vacinas reduzem o risco de desenvolvimento de COVID-19 – mas os estudos discordam quanto à proteção contra ‘long COVID’”.

Aposta de Cuba nas vacinas contra COVID produzidas no país está valendo a pena.

OMS emite diretrizes sobre o tratamento de crianças com síndrome inflamatória multissistêmica associada a COVID-19.

Opinião de 32 ministros de saúde: o mundo precisa agir agora e se preparar para futuras emergências de saúde.

Promoção da aceitação das vacinas contra COVID-19: recomendações da comissão do Lancet sobre recusa de vacina, aceitação e demanda nos EUA.

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