Clínica Médica
Estudo randomizado | Vortioxetina 5, 10 e 20 mg reduz significativamente o risco de recaída em comparação ao placebo em pacientes com transtorno depressivo maior remitente.
14 Mar, 2022 | 13:42h
Comentário no Twitter
RCT: In patients with remitted MDD with 10 mg/day of vortioxetine, time to relapse was longer and cumulative relapse rates were lower for vortioxetine 5 mg (19.3%), 10 mg (17.9%), and 20 mg (17.4%) versus placebo (32.5%) over 28 weeks (p<0.05 for all) https://t.co/LzwFaxVt4d pic.twitter.com/Gq3lLTtVcS
— PfOL (@psychopharmacol) March 11, 2022
Interpretação de teste diagnóstico: teste de exercício cardiopulmonar.
14 Mar, 2022 | 13:41hCardiopulmonary Exercise Testing – JAMA (gratuito por tempo limitado)
Revisão | Infecção cutânea por micobactérias.
14 Mar, 2022 | 13:40hMycobacterial skin infection – Current Opinion in Infectious Diseases
Estudo randomizado | Efetividade da fosfomicina no tratamento de infecções de trato urinário por Escherichia coli multirresistente.
14 Mar, 2022 | 13:37hComentários:
The Role of Intravenous Fosfomycin: Finding Our Way Out of Dante’s Forest Dark – JAMA Network Open
Fosfomycin Not Noninferior to Comparators for Bacteremic UTI – HealthDay
‘Forgotten’ antibiotic recovered for resistant bacterial infections – University of Seville
Comentário no Twitter
In this RCT, fosfomycin did not demonstrate noninferiority in MDR-E coli bacteremic UTI, mostly due to adverse event-related withdrawals in mITT, but showed efficacy in per protocol analysis. #FORESTtrial @jesusrbano https://t.co/oiPtiQo2XA pic.twitter.com/Q44QQb18cN
— JAMA Network Open (@JAMANetworkOpen) January 13, 2022
Revisão | Lesão renal aguda induzida por medicamentos.
14 Mar, 2022 | 13:27hDrug-Induced Acute Kidney Injury – Clinical Journal of the American Society of Nephrology
Estudo randomizado | Metenamina hipurato (um tratamento preventivo não antibiótico) é não inferior a antibióticos profiláticos para tratar infecções recorrentes de trato urinário em mulheres.
11 Mar, 2022 | 15:19hComunicado de imprensa: Antiseptic drug as good as antibiotics for preventing recurrent urinary tract infections – BMJ Newsroom
Editorial: Methenamine hippurate for recurrent urinary tract infections – The BMJ
Comentários:
Trial supports antibiotic alternative for recurrent urinary infections – CIDRAP
Nonantibiotic Prophylaxis Noninferior for Recurrent UTI – HealthDay
Comentário no Twitter
The antiseptic drug methenamine hippurate is as good as antibiotics for preventing recurrent urinary tract infections in women, finds this trial
Includes a visual abstract displaying the findings #BMJInfographic https://t.co/LJNx2OEKhO @chrisharding123 pic.twitter.com/CjxWtjao6r
— The BMJ (@bmj_latest) March 10, 2022
Diretriz OMS | Uso de testes diagnósticos rápidos de detecção de antígeno do SARS-CoV-2 para o autoteste de COVID-19.
11 Mar, 2022 | 15:18hRevisão sistemática | Corticosteroides inalatórios para tratamento da COVID-19.
11 Mar, 2022 | 15:16hInhaled corticosteroids for the treatment of COVID‐19 – Cochrane Library
Conteúdos relacionados:
[Preprint] M-A: Inhaled corticosteroids in COVID-19 outpatients.
Position Paper: Recommendations for the use of topical inhalant budesonide in COVID-19.
RCT: Inhaled budesonide shortens recovery time in non-hospitalized patients with COVID-19
Phase 2 RCT: Inhaled budesonide shows promise for the treatment of early COVID-19
Comentário no Twitter (fio – clique para saber mais)
Are inhaled #corticosteroids an effective treatment for people with mild #COVID19?
New #systematicreview from @CochraneAirways looks at using this well established treatment for asthma & COPD as a #COVIDtreatment https://t.co/dxUtudHLiW 1/4 pic.twitter.com/4nUs56Xfsg— The Cochrane Library (@CochraneLibrary) March 9, 2022
Outro estudo sugere que a 3ª dose de vacina é necessária para proteger as populações contra a variante Ômicron.
11 Mar, 2022 | 15:13hComunicado de imprensa: Third vaccine dose critical for protecting populations against omicron variant – BMJ Newsroom
Comentário no Twitter
mRNA vaccines are highly effective in preventing covid-19 associated hospital admissions related to the alpha, delta, and omicron variants. But three doses are needed to achieve a similar level of protection against omicron, finds a large US study: https://t.co/YMm176gmby
— The BMJ (@bmj_latest) March 10, 2022
Estudo de coorte retrospectivo | Frequência e desfechos da adenopatia axilar detectada por ressonância magnética após vacinação contra COVID-19.
11 Mar, 2022 | 15:10hConteúdos relacionados:
2 Case Series and Guidance | Lymphadenopathy in COVID-19 Vaccine Recipients