Acesso livre
Acesso livre

Clínica Médica

Estudo randomizado por cluster | Uma intervenção multifacetada não reduziu as infecções de corrente sanguínea relacionadas a cateter em pacientes dialíticos.

14 Abr, 2022 | 17:38h

Multifaceted intervention to reduce haemodialysis catheter related bloodstream infections: REDUCCTION stepped wedge, cluster randomised trial – The BMJ

Estudo de coorte | Diâmetro aumentado da aorta torácica está associado com risco aumentado de eventos cardiovasculares e mortalidade entre mulheres e homens.

14 Abr, 2022 | 17:34h

Thoracic Aortic Diameter and Cardiovascular Events and Mortality among Women and Men – Radiology

Comunicado de imprensa: Increased aortic diameter raises risk of heart attack, stroke – Radiological Society of North America

Breve revisão | Endocardite infecciosa: pontos de atenção no tratamento.

14 Abr, 2022 | 17:26h

Infective Endocarditis: Words of Caution For Management – American College of Cardiology

Conteúdos relacionados:

Randomized Trial: Partial Oral vs. Intravenous Antibiotic Treatment of Endocarditis

Cohort Study: Socio-economic variations determine the clinical presentation, etiology and outcome of infective endocarditis.

Podcast: Infective Endocarditis Pearls.

AHA Statement: Prevention of Viridans Group Streptococcal Infective Endocarditis – Antibiotic prophylaxis for invasive dental procedures is suggested only for high-risk patients with the following conditions: 1) cardiac prosthetic valve; 2) previous infective endocarditis; 3) congenital heart disease; or 4) previous heart transplant

New-Generation Antibiotics for Treatment of Gram-Positive Infections: A Review with Focus on Endocarditis and Osteomyelitis

Review: Infective endocarditis after surgical and transcatheter aortic valve replacement

Infective Endocarditis: A Contemporary Review

Summary: Current AATS Guidelines on Surgical Treatment of Infective Endocarditis

Review: Current Evidence on Oral Antibiotics for Infective Endocarditis

[Abstract Only] Prevalence of Infective Endocarditis in Patients with Positive Blood Cultures According to the Organism

Observational Study Suggests Early Surgery is Associated with Reduced Mortality in Patients with Infective Endocarditis and Large Vegetation

Research: Invasive Procedures Associated With the Development of Infective Endocarditis

Meta-Analysis: Association of Vegetation Size With Embolic Risk in Patients With Infective Endocarditis

Prosthetic Valve Endocarditis After Surgical Aortic Valve Replacement

Tuberculose resistente a medicamentos – Desenvolvimentos mais recentes em epidemiologia, diagnóstico e tratamento.

14 Abr, 2022 | 17:25h

Drug resistant TB – latest developments in epidemiology, diagnostics and management – International Journal of Infectious Diseases

Conteúdos relacionados:

Summary | WHO recommendations on the treatment of drug-resistant tuberculosis, 2020 update.

WHO Consolidated Guidelines on Drug-resistant Tuberculosis Treatment

Randomized Trial: 9-month Treatment for Multi-drug Resistant TB is as Effective as 24-month Treatment

Canadian Tuberculosis Standards – 8th Edition.

Guideline: Treatment of Drug-Resistant Tuberculosis

NICE Guideline: Tuberculosis

The Lancet Commission: Management of Multidrug-resistant and Incurable Tuberculosis

Regimens to Treat Multidrug-resistant Tuberculosis: Past, Present and Future Perspectives

Estudo randomizado | Vacinação em dose única contra o HPV se mostrou efetiva entre mulheres jovens na África.

14 Abr, 2022 | 17:07h

Efficacy of Single-Dose Human Papillomavirus Vaccination among Young African Women – NEJM Evidence

Comunicado de imprensa:

Study boosts support for single-dose HPV vaccine regimen – University of Washington

One-dose Human Papillomavirus (HPV) vaccine offers solid protection against cervical cancer – World Health Organization

Conteúdo relacionado: Three-year follow-up of 2-dose versus 3-dose HPV vaccine

 

Comentário no Twitter (fio – clique para saber mais)

 

M-A | Inibidores de SGLT2 reduzem internações em pacientes com insuficiência cardíaca independentemente da presença de diabetes.

14 Abr, 2022 | 17:02h

Sodium–Glucose Cotransporter-2 Inhibitors in Patients With Heart Failure: A Systematic Review and Meta-analysis – Annals of Internal Medicine (link para o resumo – $ para o texto completo)

Comunicado de imprensa: SGLT2 inhibitors reduces hospitalization for heart failure regardless of presence of diabetes – American College of Physicians

Diretrizes baseadas em evidência sobre interações medicamentosas entre fármacos anticâncer: uma ferramenta prática e universal para o manejo.

14 Abr, 2022 | 17:01h

Evidence- and consensus-based guidelines for drug-drug interactions with anticancer drugs; A practical and universal tool for management – Seminars in Oncology

Opinião | Alinhando os incentivos para melhorar a excelência diagnóstica.

14 Abr, 2022 | 16:56h

Aligning Incentives for Improving Diagnostic Excellence – JAMA (gratuito por tempo limitado)

M-A | Efeito clínico e segurança das novas diretrizes sobre o tempo de jejum pré-operatório para cirurgias eletivas.

14 Abr, 2022 | 16:54h

The clinical effect and safety of new preoperative fasting time guidelines for elective surgery: a systematic review and meta-analysis – Gland Surgery

Conteúdos relacionados:

An international multidisciplinary consensus statement on fasting before procedural sedation in adults and children – Anaesthesia

Does my hospitalized patient need an NPO-after-midnight order preoperatively?

ESPEN practical guideline: Clinical nutrition in surgery – “Preoperative fasting from midnight is unnecessary in most patients. Patients undergoing surgery, who are considered to have no specific risk of aspiration, shall drink clear fluids until 2 h before anesthesia. Solids shall be allowed until 6 h before anesthesia.”

Pro-Con Debate: 1- vs 2-Hour Fast for Clear Liquids Before Anesthesia in Children.

Editorial: The rationale for the recommendations of the European Pediatric Fasting Guideline – “the authors of the 2021 ESAIC pediatric guideline have found reasons to recommend reductions to the minimum fasting times for infant formula to 4 h, for breast milk to 3 h and for clear fluids to 1 h”.

Practice Guidelines for Preoperative Fasting and the Use of Pharmacologic Agents to Reduce the Risk of Pulmonary Aspiration: Application to Healthy Patients Undergoing Elective Procedures: An Updated Report by the American Society of Anesthesiologists Task Force on Preoperative Fasting and the Use of Pharmacologic Agents to Reduce the Risk of Pulmonary Aspiration

Perioperative fasting in adults and children: guidelines from the European Society of Anaesthesiology

Clear fluids fasting for elective paediatric anaesthesia: The European Society of Anaesthesiology consensus statement – European Journal of Anaesthesiology

Canadian Pediatric Anesthesia Society statement on clear fluid fasting for elective pediatric anesthesia – Canadian Journal of Anesthesia (gratuito)

Mais dados sugerem que a variante Ômicron causa doença mais leve em comparação à variante Delta.

14 Abr, 2022 | 16:51h

Symptom prevalence, duration, and risk of hospital admission in individuals infected with SARS-CoV-2 during periods of omicron and delta variant dominance: a prospective observational study from the ZOE COVID Study – The Lancet

Comentário: Covid-19: Symptomatic infection with omicron variant is milder and shorter than with delta, study reports – The BMJ

Conteúdos relacionados:

Another study suggests a lower risk of hospitalization and death from infection with SARS-CoV-2 Omicron variant vs. Delta.

Perspective: Challenges in inferring intrinsic severity of the SARS-CoV-2 Omicron variant.

Early assessment of the clinical severity of the SARS-CoV-2 omicron variant in South Africa.

Cohort Study: Incidence rates and clinical outcomes of SARS-CoV-2 infection with the Omicron and Delta variants in children younger than 5 years in the US.

[Preprint] SARS-CoV-2 Omicron virus causes attenuated disease in mice and hamsters.

[Preprint] Study showed reduced clinical severity of Covid-19 patients admitted to hospitals in Gauteng, South Africa, during the Omicron-dominant fourth wave – “any combination of a less-virulent virus, comorbidities, high immunity from prior infection(s) or vaccination may be important contributors to this clinical presentation”.

Early data from South Africa hints Omicron variant may cause less severe Covid, but more research is needed.

Too early to tell, but preliminary information from doctors in South Africa suggests the new Covid variant Omicron may be associated with less severe disease.

Mantenha-se atualizado em sua especialidade

 

Escolha quantas especialidades quiser.