Clínica Médica

Covid não revelou todos os seus segredos. Aqui estão 6 mistérios que os especialistas esperam desvendar.

21 Abr, 2022 | 12:30h

Covid hasn’t given up all its secrets. Here are 6 mysteries experts hope to unravel – STAT

Estudo controlado não randomizado: posição prona em paciente não intubado (média de 4,2 horas/dia) pode não ser benéfica para adultos internados com Covid-19.

21 Abr, 2022 | 12:29h

Assessment of Awake Prone Positioning in Hospitalized Adults With COVID-19: A Nonrandomized Controlled Trial – JAMA Internal Medicine

Comentários:

Prone Positioning for Nonintubated Patients With COVID-19—Potential Dangers of Extrapolation and Intermediate Outcome Variables – JAMA Internal Medicine

Study suggests worse outcomes for awake COVID patients in prone position – CIDRAP

Putting Hospitalized COVID Patients on Their Belly May Not Be a Good Idea After All – HealthDay

Conteúdos relacionados:

Awake prone positioning for non-intubated patients with COVID-19-related acute hypoxaemic respiratory failure: a systematic review and meta-analysis – The Lancet Respiratory Medicine

Prone positioning of patients with moderate hypoxaemia due to covid-19: multicentre pragmatic randomised trial (COVID-PRONE) – The BMJ

RCT: Prone positioning of patients with moderate hypoxia due to COVID-19 – medRxiv

Awake prone positioning for COVID-19 acute hypoxaemic respiratory failure: a randomised, controlled, multinational, open-label meta-trial – The Lancet Respiratory Medicine

Awake prone positioning in patients with hypoxemic respiratory failure due to COVID-19: the PROFLO multicenter randomized clinical trial – Critical Care

Prone Positioning of Nonintubated Patients With Coronavirus Disease 2019—A Systematic Review and Meta-Analysis – Critical Care Medicine

Comentário no Twitter (fio – clique para saber mais)

Important negative study: non randomized trial finds no clinical benefit to awake proning vs usual care in COVID

No difference in rates of intubation, length of stay, or 28 day mortality

Medicine is humbling. This emphasizes the importance of trials
📄https://t.co/ksh9Ic9XBL
1/ pic.twitter.com/sjHHv4WQs8

— Nick Mark MD (@nickmmark) April 18, 2022

Diretrizes alemãs para diagnóstico e tratamento de varizes.

21 Abr, 2022 | 12:25h

S2k guidelines: diagnosis and treatment of varicose veins – Leitlinien und Empfehlungen

Estudo de coorte | Infertilidade em mulheres está associada a risco aumentado de insuficiência cardíaca com fração de ejeção preservada.

21 Abr, 2022 | 12:21h

Infertility and Risk of Heart Failure in the Women’s Health Initiative – Journal of the American College of Cardiology (link para o resumo – $ para o texto completo)

Podcast: Infertility and Risk of Heart Failure in the Women’s Health Initiative

Comentários:

Infertility in Women Linked to Subsequent Risk of HFpEF – TCTMD

MGH study finds infertility associated with increased risk of heart failure – MedicalResearch

Revisão | Pressão arterial e sua variabilidade: técnicas de aferição clássicas e novas abordagens.

21 Abr, 2022 | 12:19h

Blood pressure and its variability: classic and novel measurement techniques – Nature Reviews Cardiology (se o acesso a este link for pago, tente este)

Revisão sistemática | Tratamento de periodontite para melhorar o controle glicêmico em pessoas com diabetes melito.

21 Abr, 2022 | 12:17h

Treatment of periodontitis for glycaemic control in people with diabetes mellitus – Cochrane Library

Resumo: Does treatment for gum disease help people with diabetes control blood sugar levels? – Cochrane Library

Comentário no Twitter

Does treatment for gum disease help people with diabetes control their blood sugar levels? Evidence from @CochraneLibrary: https://t.co/lk6nGrAIpp pic.twitter.com/UZXKr5b4Rs

— Cochrane Oral Health (@CochraneOHG) April 19, 2022

Estudo de coorte | Associação de queixas subjetivas de memória e focos de hiperintensidade na substância branca com declínio cognitivo entre idosos.

21 Abr, 2022 | 12:03h

Association of Subjective Memory Complaints With White Matter Hyperintensities and Cognitive Decline Among Older Adults in Chicago, Illinois – JAMA Network Open

Comentário: Memory complaints associated with structural brain abnormalities and increased dementia risk – HealthImaging

Comentário no Twitter

In this cohort study, subjective memory complaints (SMCs) were associated with larger white matter hyperintensity volumes and faster cognitive decline, suggesting that SMCs are an important sign of cognitive impairment. https://t.co/mpCXDbylnf

— JAMA Network Open (@JAMANetworkOpen) April 15, 2022

Opinião | Câncer de próstata de baixo grau (escore 6 de Gleason): hora de parar de chamar isso de câncer.

21 Abr, 2022 | 11:44h

Low-Grade Prostate Cancer: Time to Stop Calling It Cancer – Journal of Clinical Oncology

Comentário: Doctors suggest new names for low-grade prostate cancer – Associated Press

Vídeo | Isso é o que se sabe sobre o impacto da COVID-19 no cérebro.

21 Abr, 2022 | 11:41h

Here’s what we know about COVID-19’s impact on the brain – Science

Conteúdos relacionados:

SARS-CoV-2 is associated with changes in brain structure in UK Biobank – Nature

Nervous system consequences of COVID-19 – Science

The COVID generation: how is the pandemic affecting kids’ brains? – Nature

Fatigue and cognitive impairment in Post-COVID-19 Syndrome: A systematic review and meta-analysis – Brain, Behavior, and Immunity

Assessment of Cognitive Function in Patients After COVID-19 Infection – JAMA Network Open

M-A | Prevalência global da condição pós-COVID-19 ou COVID longa.

21 Abr, 2022 | 11:37h

Global Prevalence of Post COVID-19 Condition or Long COVID: A Meta-Analysis and Systematic Review – The Journal of Infectious Diseases

Comentário: Global data reveal half may have long COVID 4 months on – CIDRAP