Alergia e Imunologia
“Long COVID” e crianças: cientistas correm para encontrar respostas – “Crianças também apresentam ‘long COVID’, mas os pesquisadores ainda estão trabalhando para determinar qual a frequência e a gravidade.”
15 Jul, 2021 | 10:38hLong COVID and kids: scientists race to find answers – Nature
Estudo de coorte | Vacina da Pfizer/BioNTech contra COVID está associada com 78% menos risco de ocorrência de Covid-19 durante a gestação.
14 Jul, 2021 | 11:45hBetween BNT162b2 Vaccination and Incidence of SARS-CoV-2 Infection in Pregnant Women – JAMA
Comentário: Pfizer COVID vaccine shows 78% efficacy in pregnancy – CIDRAP
Muitas crianças da Nova Zelândia estão adoecendo em virtude da “falta de imunidade” gerada pelas medidas de restrição contra a pandemia de Covid.
14 Jul, 2021 | 11:42hNew Zealand children falling ill in high numbers due to Covid ‘immunity debt’ – The Guardian
Relacionado: New Zealand, where Covid-19 is dormant, fights another respiratory virus – The New York Times
“Long Covid”: 39% dos pacientes tratados em ambulatório relatam sintomas persistentes mais de 7 meses depois do diagnóstico de COVID-19.
13 Jul, 2021 | 11:28hComentários: Long COVID symptoms in a third of people with COVID-19 – American College of Physicians E Covid-19: 1-in-3 Patients Reported Long-Hauler Symptoms – Physician’s Weekly
Comentário no Twitter
A new prospective cohort study of >400 people with mild to moderate (outpatient) covid at 7-9 months: nearly 1 of 3 had persistent symptoms #LongCovid @AnnalsofIM
https://t.co/ix1Hhsm0iZ
by @mayssamnehme and colleagues pic.twitter.com/Uc4UEclDvA— Eric Topol (@EricTopol) July 5, 2021
[Preprint] “Long Covid”: sintomas persistentes após infecção por SARS-CoV-2 em uma amostra aleatória de 508.707 pessoas da comunidade.
13 Jul, 2021 | 11:27hComentário: Study explores the prevalence of long COVID in England – News Medical
OMS alerta quanto à mistura e à combinação de vacinas contra a COVID.
13 Jul, 2021 | 11:26hWHO warns against mixing and matching COVID vaccines – Reuters
Comentário: WHO cautions data still limited on mixing COVID-19 vaccines, but Canadian officials say it’s OK – CTV News
Relacionado: Germany issues world’s strongest recommendation for mixing Covid-19 vaccines. E [Preprint] Mixing Covid jabs has good immune response, study finds – “The Com-Cov trial looked at the efficacy of either two doses of Pfizer, two of AstraZeneca, or one of them followed by the other. All combinations worked well, priming the immune system”. E Perspective | Can I get AstraZeneca now and Pfizer later? Why mixing and matching COVID vaccines could help solve many rollout problems. E RCT: Mixing 2 different Covid vaccines is associated with increased risk of side effects. E Should you mix and match COVID-19 vaccines? Scientists are seeking answers
Comentário no Twitter
The World Health Organization's chief scientist on Monday advised against people mixing and matching COVID-19 vaccines from different manufacturers, calling it a "dangerous trend" since there was little data available about the health impact. https://t.co/Oog6fWDSMz
— Reuters Health (@Reuters_Health) July 13, 2021
Casos extremamente raros de Guillain-Barré relatados com a vacina da Johnson & Johnson contra a Covid-19.
13 Jul, 2021 | 11:24hJ&J’s Covid-19 vaccine may trigger neurological condition in rare cases, FDA says – STAT
Ver também: Johnson & Johnson Vaccine Is Linked To Neurological Disorder In Extremely Rare Cases – NPR E F.D.A. Attaches Warning of Rare Nerve Syndrome to Johnson & Johnson Vaccine – The New York Times
Pfizer afirma que é hora de um reforço (terceira dose) na vacina contra a Covid; FDA e CDC dizem que ainda não.
12 Jul, 2021 | 11:35hPfizer says it’s time for a Covid booster; FDA and CDC say not so fast – CNN
Ver também: CDC, FDA contradict Pfizer on COVID-19 vaccine booster – CIDRAP E Do I need a COVID-19 booster shot? 6 questions answered on how to stay protected – The Conversation E Pfizer suggests booster shots will be needed this year, but government officials say science will dictate the timing – The Washington Post E Pfizer to seek OK for 3rd vaccine dose; shots still protect – Associated Press E Citing the Delta Variant, Pfizer Will Pursue Booster Shots and a New Vaccine – The New York Times (poucos artigos gratuitos por mês) E Question open on need for COVID booster shot, data awaited, WHO says – Reuters
Há necessidade urgente de um correlato de proteção para as vacinas contra o SARS-CoV-2 – “Estudos recentes sugerem que os anticorpos neutralizantes podem servir como um correlato de proteção para as vacinas contra o SARS-CoV-2 em humanos.”
12 Jul, 2021 | 11:31hA correlate of protection for SARS-CoV-2 vaccines is urgently needed – Nature Medicine
Relacionado: Neutralizing antibody levels are highly predictive of immune protection from symptomatic SARS-CoV-2 infection.
Coorte nacional prospectiva no Chile mostrou que a efetividade da CoronaVac foi de 65,9% para Covid-19 sintomática, 87,5% para hospitalizações, 90,3% para admissões em UTI e 86,3% para mortes.
8 Jul, 2021 | 09:57hEffectiveness of an Inactivated SARS-CoV-2 Vaccine in Chile – New England Journal of Medicine
Relacionado: Phase 1/2 RCT: CoronaVac is well tolerated and safe and induces strong humoral responses in children and adolescents aged 3–17 years. E WHO approval of Chinese CoronaVac COVID vaccine will be crucial to curbing pandemic. E Brazilian town experiment shows mass vaccination can wipe out COVID-19.
Comentário no Twitter
Chile's data on Sinovac CoronaVac in NEJM: not controlled study. Model details pic 2
– doses 28 days apart (like Serrana trial)
– symptomatic disease 65.9% (65-67)
– hospitalization 87.5% (87-88)
– intensive care 90.3% (89-91)
– Covid death 86.3% (85-88)
https://t.co/CB1U8Ar163 pic.twitter.com/4HwASRCnwQ— Hilda Bastian, PhD (@hildabast) July 7, 2021