Alergia e Imunologia

Reforços da vacina contra COVID: questões mais importantes.

9 Ago, 2021 | 11:30h

COVID vaccine boosters: the most important questions – Nature

 

Comentário no Twitter

I agree with @nataliexdean: “We just don’t have clear evidence of enough of a loss of efficacy to change our focus or distract from the main goal, which is trying to get as many people first doses” as possible." https://t.co/FEKB4vg0Dz

— Sanghyuk Shin (@sanghyuk_shin) August 6, 2021

 

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Mais dados mostram que uma dose da vacina da Pfizer pode ser suficiente para pessoas que já tiveram COVID.

9 Ago, 2021 | 11:29h

Comentário: One Dose of Pfizer Vaccine May Be Enough for Folks Who’ve Had COVID – HealthDay

Estudo original: SARS-CoV-2 Antibody Responses in Infection-Naive or Previously Infected Individuals After 1 and 2 Doses of the BNT162b2 Vaccine – JAMA Network Open

Conteúdos relacionados:

Perspective | Is one vaccine dose enough if you’ve had COVID? What the science says.

Another study shows a single dose of mRNA vaccine may be enough for patients with previous Covid-19

Spain to give just one vaccine dose to under 55-year olds who had COVID-19

Perspective: Is one vaccine dose enough after COVID-19 infection?

France’s health authority recommends single vaccine shot for people who have had COVID-19

Covid-19: People who have had infection might only need one dose of mRNA vaccine

 

Comentário no Twitter

SARS-CoV-2 Antibody Responses After 1 and 2 Doses of the BNT162b2 Vaccine https://t.co/ARMdH8Yboo via @JAMANetworkOpen part of @JAMANetwork Small study but one that confirms the policy of many European countries in which one dose of vaccine is sufficient after having COVID.

— Carlos del Rio (@CarlosdelRio7) August 7, 2021

 

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Relato de caso | Síndrome de vazamento capilar sistêmico após vacinação com a vacina da Oxford–AstraZeneca.

9 Ago, 2021 | 11:27h

Systemic capillary leak syndrome afer ChAdOx1 nCOV-19 (Oxford–AstraZeneca) vaccination – Canadian Medical Association Journal

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Encefalite autoimune mediada por anticorpos: uma abordagem prática.

9 Ago, 2021 | 11:08h

Antibody-mediated autoimmune encephalitis: A practical approach – Cleveland Clinic Journal of Medicine

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Variantes do SARS-CoV-2 em pacientes imunossuprimidos.

5 Ago, 2021 | 11:58h

SARS-CoV-2 Variants in Patients with Immunosuppression – New England Journal of Medicine

 

Comentário no Twitter

In the pandemic, immunocompromised people (~3% of Americans) are not getting adequate recognition for the potential of in-host evolution of the virus (highlighted studies) and the need for far better approaches to protect them https://t.co/XDT1VxC9ZK @NEJM pic.twitter.com/ciw1WD9EzC

— Eric Topol (@EricTopol) August 4, 2021

 

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Estudo randomizado | Combinação de anticorpos REGEN-COV subcutâneos evitou infecção sintomática por Covid-19 em contactantes de pessoas infectadas.

5 Ago, 2021 | 11:57h

Subcutaneous REGEN-COV Antibody Combination to Prevent Covid-19 – New England Journal of Medicine

Conteúdos relacionados:

RCT: Bamlanivimab plus Etesevimab reduce mortality and hospitalization in ambulatory patients with early Covid-19 (within 3 days of a positive test) who are at risk for clinical deterioration (i.e., older people, obese, diabetics, immunocompromised, with CV disease).

[Preprint] RECOVERY trial finds Regeneron’s monoclonal antibody combination reduces deaths for hospitalized COVID-19 patients who have not mounted their own immune response.

 

Comentário no Twitter

Subcutaneous REGEN-COV prevented symptomatic #COVID19 and asymptomatic #SARSCoV2 infection in previously uninfected household contacts. https://t.co/rRNFTjS9hX pic.twitter.com/B7qXeyWKUb

— NEJM (@NEJM) August 4, 2021

 

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Estudo de coorte | Seguimento de 6 meses da síndrome inflamatória multissistêmica em crianças.

3 Ago, 2021 | 11:32h

Six Month Follow-up of Patients With Multisystem Inflammatory Syndrome in Children – Pediatrics (PDF)

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Marcador sanguíneo (anticorpos neutralizantes) prediz quem irá desenvolver ‘breakthrough infection’ (infecção em indivíduos vacinados).

3 Ago, 2021 | 11:29h

A blood marker predicts who gets ‘breakthrough’ COVID – Nature

Conteúdos relacionados:

A correlate of protection for SARS-CoV-2 vaccines is urgently needed – “Recent studies suggest that neutralizing antibodies could serve as a correlate of protection for vaccines against SARS-CoV-2 in humans”.

Neutralizing antibody levels are highly predictive of immune protection from symptomatic SARS-CoV-2 infection.

Covid-19 breakthrough infections in vaccinated health care workers.

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Recomendações da ACOG e da SMFM para a vacinação contra COVID-19 em gestantes – “ACOG encoraja seus membros a recomendar enfaticamente a vacinação para suas pacientes.”

2 Ago, 2021 | 19:18h

ACOG and SMFM Recommend COVID-19 Vaccination for Pregnant Individuals – American College of Obstetricians and Gynecologists (ACOG) and the Society for Maternal-Fetal Medicine (SMFM)

Leituras adicionais:

Practice Advisory: COVID-19 Vaccination Considerations for Obstetric-Gynecologic Care

COVID-19 Vaccines and Pregnancy: Conversation Guide for Clinicians

Comentários:

Obstetrician groups recommend COVID vaccine during pregnancy – Associated Press

Statements By Obstetrics Societies Strongly Advise Covid-19 Vaccinations For Pregnant Women – Forbes

 

Comentário no Twitter

Pregnant? ACOG and @MySMFM now recommend #COVID19 vaccination of pregnant individuals and urge our members to recommend that pregnant patients #GetVaccinated. The #covidvaccine is the best tool we have to save lives and end the pandemic: https://t.co/pUbLqqkKym #VaccinesWork pic.twitter.com/Ef2MOPv27L

— ACOG (@acog) July 30, 2021

 

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Opinião | Gestantes devem se vacinar contra COVID? As evidências mostram que é seguro e eficaz.

2 Ago, 2021 | 19:16h

Should pregnant women have a COVID vaccine? The evidence says it’s safe and effective – The Conversation

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