Alergia e Imunologia

Por que a terceira dose de vacina contra COVID-19 é importante para pessoas imunocomprometidas?

2 Set, 2021 | 11:49h

Why is a third COVID-19 vaccine dose important for people who are immunocompromised? – The Conversation

Conteúdos relacionados:

FDA authorizes additional Covid-19 vaccine dose for certain immunocompromised individuals – Other fully vaccinated individuals do not need an additional vaccine dose right now.

RCT: third dose of Moderna mRNA vaccine increases immunity in transplant recipients.

Study: Among kidney transplant recipients who did not respond after 2 doses, a third dose of an mRNA-1273 vaccine induced a serologic response in 49% of patients.

Case series: Safety and immunogenicity of a third dose of SARS-CoV-2 vaccine in solid organ transplant recipients.

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Estudo demonstra imunogenicidade humoral significativamente mais alta induzida pela vacina da Moderna em comparação à vacina da Pfizer- BioNTech.

2 Set, 2021 | 11:28h

Comparison of SARS-CoV-2 Antibody Response Following Vaccination With BNT162b2 and mRNA-1273 – JAMA

Conteúdos relacionados:

Moderna may be superior to Pfizer against Delta variant — breakthrough odds rise with time.

[Preprint] Pfizer vs. Moderna COVID-19 vaccine effectiveness against the Delta variant in Qatar – Effectiveness against symptomatic disease due to Delta was 53.5% for Pfizer and 84.8% for Moderna; effectiveness against severe disease due to Delta was 89.7% for Pfizer and 100.0% for Moderna.

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Nova diretriz do CDC afirma que as vacinas contra influenza e Covid podem ser administradas juntas – “Vacinas contra COVID-19 e outras vacinas agora podem ser administradas sem preocupações quanto ao intervalo entre elas.”

30 Ago, 2021 | 13:33h

Prevention and Control of Seasonal Influenza with Vaccines: Recommendations of the Advisory Committee on Immunization Practices, United States, 2021–22 Influenza Season – Centers for Disease Control and Prevention

Conteúdo relacionado: Interim Clinical Considerations for Use of COVID-19 Vaccines Currently Authorized in the United States – Centers for Disease Control and Prevention

Comentário: Flu shot and a COVID jab? New 2021-2022 flu vaccine guidance points to both – McKnight’s

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[Preprint] Dados observacionais sugerem que a imunidade natural conferida pela infecção por SARS-CoV-2 é mais forte e duradoura em comparação à imunidade induzida por vacina.

30 Ago, 2021 | 12:57h

Comparing SARS-CoV-2 natural immunity to vaccine-induced immunity: reinfections versus breakthrough infections – medRxiv

Comentário: Having SARS-CoV-2 once confers much greater immunity than a vaccine—but no infection parties, please – Science

 

Comentário no Twitter (fio – clique para saber mais)

Interesting and a lot of threads already but I wanna throw a spanner in the works with an annoying question that I hope someone will be able to answer so I can better understand the relevance of this study.https://t.co/5cE0omt6FH

— Andrew L. Croxford (@andrew_croxford) August 26, 2021

 

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[Comunicado de imprensa – Ainda não publicado] Estudo mostra que a proteção vacinal diminui com o tempo, mas as vacinas ainda oferecem uma boa proteção contra doença grave.

30 Ago, 2021 | 12:55h

Comunicado de imprensa: Is COVID vaccine protection fading? – ZOE Covid Study

Comentários:

Covid infection protection waning in double jabbed – BBC

Expert reaction to press release from the ZOE app on vaccine effectiveness over time – Science Media Centre

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Companhia afirma que dose de reforço com a vacina da Johnson & Johnson propicia aumento significativo na resposta imune.

26 Ago, 2021 | 12:46h

Johnson & Johnson booster shot prompts large increase in immune response, company says – CNN

Comunicado de imprensa: Johnson & Johnson Announces Data to Support Boosting its Single-Shot COVID-19 Vaccine

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Diretrizes para a abordagem perioperatória de pacientes com câncer ovariano avançado que serão submetidas a cirurgia citorredutora.

26 Ago, 2021 | 12:12h

European Society of Gynaecological Oncology guidelines for the peri-operative management of advanced ovarian cancer patients undergoing debulking surgery – International Journal of Gynecological Cancer

Editorial: Standardizing ovarian cancer surgery and peri-operative care: a European Society of Gynecological Oncology (ESGO) consensus statement

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Reforço de vacinas contra Covid-19: o que se sabe e quem está fazendo o quê.

24 Ago, 2021 | 11:52h

Covid-19 booster vaccines: What we know and who’s doing what – The BMJ

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Opinião | O FDA realmente precisava demorar tudo isso – “Se a aprovação das vacinas parece tão escrupulosa, é porque a alternativa a isso é pior.”

24 Ago, 2021 | 11:49h

The FDA Really Did Have to Take This Long – The Atlantic

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Vacinas contra COVID protegem da variante Delta, mas sua eficácia diminui com o tempo.

24 Ago, 2021 | 11:47h

COVID vaccines protect against Delta, but their effectiveness wanes – Nature

Estudo original: [Preprint] Pfizer vaccine effectiveness against Delta declines faster than AstraZeneca, both offering the same protection after 4 months.

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