Seguimento de longo prazo de um estudo randomizado | Lesões de colo do útero pré-cancerosas, causadas por tipos de HPV não preveníveis por vacina, após uso de vacina contra HPV bivalente AS04.

Precancerous cervical lesions caused by non-vaccine-preventable HPV types after vaccination with the bivalent AS04-adjuvanted HPV vaccine: an analysis of the long-term follow-up study from the randomised Costa Rica HPV Vaccine Trial – The Lancet Oncology (link para o resumo – $ para o texto completo)

Comentário: Clinical Unmasking May Cause Increased Rates of High-Grade Cervical Neoplasia From Non–Vaccine Preventable HPV – Cancer Network

Comentário no Twitter

Virological replacement & clinical unmasking are two phenomena of interest following #HPVvaccination. We show that clinical unmasking might attenuate long-term reductions in cervical precancer following successful implementation of HPV vax programs in highly screened populations https://t.co/Z7dGQNG1kG

— Monica Sierra (@MonicaSSierra) June 14, 2022