Ranitidina absolvida? Estudo do FDA mostra que a ranitidina não é convertida ao carcinógeno NDMA, independentemente da dieta.

Effect of Oral Ranitidine on Urinary Excretion of N-Nitrosodimethylamine (NDMA): A Randomized Clinical Trial – JAMA

Editorial: Ranitidine and Risk of N-Nitrosodimethylamine (NDMA) Formation

Comentário: Ranitidine: FDA finds no evidence of elevated NDMA, regardless of diet

Comentário no Twitter

Despite ranitidine (zantac) being pulled from market last year, a new study from the FDA did not find evidence that it increases concentrations of the carcinogenic metabolite people were worried about (i.e., it's probably safe). From @JAMA_current https://t.co/AdRic2GdXS

— Zack Williams (@QuantPsychiatry) June 28, 2021

In this crossover, randomized clinical trial, oral ranitidine did not significantly increase 24-hour urinary excretion of NDMA when administered with a noncured-meats diet or a cured-meats diet. https://t.co/EszRvfJOFJ

— JAMA (@JAMA_current) June 28, 2021