Forame oval patente (FOP) após AVC: metanálise sugere que a aplicação de um sistema de classificação causal multivariável pode distinguir melhor os subgrupos de pacientes que podem se beneficiar do fechamento do FOP daqueles propensos a não ter nenhum benefício.

Heterogeneity of Treatment Effects in an Analysis of Pooled Individual Patient Data From Randomized Trials of Device Closure of Patent Foramen Ovale After Stroke – JAMA (link para o resumo – $ para o texto completo)

Comentário: Classification System May Identify Patients Likely to Benefit from PFO Closure – Physician’s Weekly

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Analysis of individual patient data from RCTs found application of a multivariable causal classification system to randomized trial results that distinguished subgroups who may benefit from patent foramen ovale (PFO) closure vs those unlikely to benefit https://t.co/L9Ic9EsNPG

— JAMA (@JAMA_current) December 15, 2021