Estudo randomizado PRINCIPLE | Doxiciclina não melhora os desfechos de pacientes ambulatoriais com suspeita de COVID-19.

Doxycycline for community treatment of suspected COVID-19 in people at high risk of adverse outcomes in the UK (PRINCIPLE): a randomised, controlled, open-label, adaptive platform trial – The Lancet Respiratory Medicine

Comentário: PRINCIPLE: a community-based COVID-19 platform trial – The Lancet Respiratory Medicine

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NEW Research—In suspected #COVID19 in the community, doxycycline was not associated with clinically meaningful reductions in time to recovery or hospital admissions or deaths, and should not be used as a routine treatment

Read the PRINCIPLE trial here https://t.co/Osw1hZLCaY pic.twitter.com/Q3VrpAO9cm

— The Lancet Respiratory Medicine (@LancetRespirMed) July 28, 2021