Estudo randomizado: Para atingir a cura clínica em torno de 28 dias em crianças com bronquite bacteriana prolongada, um curso de 4 semanas de amoxicilina-clavulanato não é melhor do que um curso de 2 semanas.

Duration of amoxicillin-clavulanate for protracted bacterial bronchitis in children (DACS): a multi-centre, double blind, randomised controlled trial – The Lancet Respiratory Medicine

Comentário: Four weeks of antibiotics for kids’ chronic cough no better than 2, study finds – CIDRAP

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NEW Research—4 weeks of amoxicillin–clavulanate for children with chronic wet cough and suspected PBB confers little advantage vs 2 weeks in achieving clinical cure by 28 days

RCT from Tom Ruffles & colleagues https://t.co/77w08dZ20z pic.twitter.com/LYgOeJbDX8

— The Lancet Respiratory Medicine (@LancetRespirMed) May 26, 2021