Estudo randomizado | No tratamento de pacientes internados com depressão unipolar, cetamina induziu remissão em 46% dos pacientes, mas NÃO foi não inferior à terapia eletroconvulsiva.

Racemic Ketamine as an Alternative to Electroconvulsive Therapy for Unipolar Depression: A Randomized, Open-Label, Non-Inferiority Trial (KetECT) – International Journal of Neuropsychopharmacology

Comunicado de imprensa: ECT more effective than ketamine in severe depression – Lund University

Comentário no Twitter

RCT-OL: 63% of inpatients with MDD receiving ECT remitted vs. 46% receiving ketamine infusions (p=0.026). Both ketamine and ECT required a median of 6 sessions to induce remission. Long-lasting AE include persisting amnesia with ECT https://t.co/tvJ0qwUu62 pic.twitter.com/NOQK8Xv8TW

— PfOL (@psychopharmacol) December 12, 2021